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APOL1 toxin, innate immunity, and kidney injury.
Limou S, Dummer PD, Nelson GW, Kopp JB, Winkler CA. Limou S, et al. Among authors: dummer pd. Kidney Int. 2015 Jul;88(1):28-34. doi: 10.1038/ki.2015.109. Epub 2015 Apr 8. Kidney Int. 2015. PMID: 25853332 Free PMC article. Review.
APOL1 Kidney Disease Risk Variants: An Evolving Landscape.
Dummer PD, Limou S, Rosenberg AZ, Heymann J, Nelson G, Winkler CA, Kopp JB. Dummer PD, et al. Semin Nephrol. 2015 May;35(3):222-36. doi: 10.1016/j.semnephrol.2015.04.008. Semin Nephrol. 2015. PMID: 26215860 Free PMC article. Review.
APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R.
Okamoto K, Rausch JW, Wakashin H, Fu Y, Chung JY, Dummer PD, Shin MK, Chandra P, Suzuki K, Shrivastav S, Rosenberg AZ, Hewitt SM, Ray PE, Noiri E, Le Grice SFJ, Hoek M, Han Z, Winkler CA, Kopp JB. Okamoto K, et al. Among authors: dummer pd. Commun Biol. 2018 Nov 7;1:188. doi: 10.1038/s42003-018-0188-2. eCollection 2018. Commun Biol. 2018. PMID: 30417125 Free PMC article.
Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.
Beckerman P, Bi-Karchin J, Park AS, Qiu C, Dummer PD, Soomro I, Boustany-Kari CM, Pullen SS, Miner JH, Hu CA, Rohacs T, Inoue K, Ishibe S, Saleem MA, Palmer MB, Cuervo AM, Kopp JB, Susztak K. Beckerman P, et al. Among authors: dummer pd. Nat Med. 2017 Apr;23(4):429-438. doi: 10.1038/nm.4287. Epub 2017 Feb 20. Nat Med. 2017. PMID: 28218918 Free PMC article.