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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1998 1
2000 3
2002 1
2004 1
2005 2
2006 5
2007 3
2008 4
2009 3
2010 2
2011 1
2012 1
2015 1
2018 1
2021 1
2024 0

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29 results

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Page 1
Medicinal chemistry of Hsp90 inhibitors.
Drysdale MJ, Brough PA. Drysdale MJ, et al. Curr Top Med Chem. 2008;8(10):859-68. doi: 10.2174/156802608784911644. Curr Top Med Chem. 2008. PMID: 18673171 Review.
RNA as a drug target.
Drysdale MJ, Lentzen G, Matassova N, Murchie AI, Aboul-Ela F, Afshar M. Drysdale MJ, et al. Prog Med Chem. 2002;39:73-119. doi: 10.1016/s0079-6468(08)70069-9. Prog Med Chem. 2002. PMID: 12536671 Review.
Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
McKinney DC, McMillan BJ, Ranaghan MJ, Moroco JA, Brousseau M, Mullin-Bernstein Z, O'Keefe M, McCarren P, Mesleh MF, Mulvaney KM, Robinson F, Singh R, Bajrami B, Wagner FF, Hilgraf R, Drysdale MJ, Campbell AJ, Skepner A, Timm DE, Porter D, Kaushik VK, Sellers WR, Ianari A. McKinney DC, et al. Among authors: drysdale mj. J Med Chem. 2021 Aug 12;64(15):11148-11168. doi: 10.1021/acs.jmedchem.1c00507. Epub 2021 Aug 3. J Med Chem. 2021. PMID: 34342224 Free PMC article.
Discovery and development of pyrazole-scaffold Hsp90 inhibitors.
McDonald E, Jones K, Brough PA, Drysdale MJ, Workman P. McDonald E, et al. Among authors: drysdale mj. Curr Top Med Chem. 2006;6(11):1193-203. doi: 10.2174/156802606777812086. Curr Top Med Chem. 2006. PMID: 16842156 Review.
Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.
Unbekandt M, Belshaw S, Bower J, Clarke M, Cordes J, Crighton D, Croft DR, Drysdale MJ, Garnett MJ, Gill K, Gray C, Greenhalgh DA, Hall JAM, Konczal J, Lilla S, McArthur D, McConnell P, McDonald L, McGarry L, McKinnon H, McMenemy C, Mezna M, Morrice NA, Munro J, Naylor G, Rath N, Schüttelkopf AW, Sime M, Olson MF. Unbekandt M, et al. Among authors: drysdale mj. Cancer Res. 2018 Apr 15;78(8):2096-2114. doi: 10.1158/0008-5472.CAN-17-2870. Epub 2018 Jan 30. Cancer Res. 2018. PMID: 29382705 Free PMC article.
Targeting Hsp90 for the treatment of cancer.
Drysdale MJ, Brough PA, Massey A, Jensen MR, Schoepfer J. Drysdale MJ, et al. Curr Opin Drug Discov Devel. 2006 Jul;9(4):483-95. Curr Opin Drug Discov Devel. 2006. PMID: 16889231 Review.
4-Amino derivatives of the Hsp90 inhibitor CCT018159.
Barril X, Beswick MC, Collier A, Drysdale MJ, Dymock BW, Fink A, Grant K, Howes R, Jordan AM, Massey A, Surgenor A, Wayne J, Workman P, Wright L. Barril X, et al. Among authors: drysdale mj. Bioorg Med Chem Lett. 2006 May 1;16(9):2543-8. doi: 10.1016/j.bmcl.2006.01.099. Epub 2006 Feb 9. Bioorg Med Chem Lett. 2006. PMID: 16480864
A fluorescence polarization assay for inhibitors of Hsp90.
Howes R, Barril X, Dymock BW, Grant K, Northfield CJ, Robertson AG, Surgenor A, Wayne J, Wright L, James K, Matthews T, Cheung KM, McDonald E, Workman P, Drysdale MJ. Howes R, et al. Among authors: drysdale mj. Anal Biochem. 2006 Mar 15;350(2):202-13. doi: 10.1016/j.ab.2005.12.023. Epub 2006 Jan 23. Anal Biochem. 2006. PMID: 16460658
29 results