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Items: 8


Maternal resveratrol administration protects against gestational diabetes-induced glucose intolerance and islet dysfunction in the rat offspring.

Brawerman GM, Kereliuk SM, Brar N, Cole LK, Seshadri N, Pereira TJ, Xiang B, Hunt KL, Fonseca MA, Hatch GM, Doucette CA, Dolinsky VW.

J Physiol. 2019 Aug;597(16):4175-4192. doi: 10.1113/JP278082. Epub 2019 Jul 21.


Gestational Diabetes Adversely Affects Pancreatic Islet Architecture and Function in the Male Rat Offspring.

Agarwal P, Brar N, Morriseau TS, Kereliuk SM, Fonseca MA, Cole LK, Jha A, Xiang B, Hunt KL, Seshadri N, Hatch GM, Doucette CA, Dolinsky VW.

Endocrinology. 2019 Aug 1;160(8):1907-1925. doi: 10.1210/en.2019-00232.


Maternal obesity, diabetes during pregnancy and epigenetic mechanisms that influence the developmental origins of cardiometabolic disease in the offspring.

Agarwal P, Morriseau TS, Kereliuk SM, Doucette CA, Wicklow BA, Dolinsky VW.

Crit Rev Clin Lab Sci. 2018 Mar;55(2):71-101. doi: 10.1080/10408363.2017.1422109. Epub 2018 Jan 8. Review.


Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice.

Seshadri N, Jonasson ME, Hunt KL, Xiang B, Cooper S, Wheeler MB, Dolinsky VW, Doucette CA.

Mol Metab. 2017 Apr 27;6(7):760-769. doi: 10.1016/j.molmet.2017.04.008. eCollection 2017 Jul.


In utero exposure to gestational diabetes mellitus conditions TLR4 and TLR2 activated IL-1beta responses in spleen cells from rat offspring.

Li Q, Pereira TJ, Moyce BL, Mahood TH, Doucette CA, Rempel J, Dolinsky VW.

Biochim Biophys Acta. 2016 Nov;1862(11):2137-2146. doi: 10.1016/j.bbadis.2016.08.004. Epub 2016 Aug 21.


Bcl-2 Regulates Reactive Oxygen Species Signaling and a Redox-Sensitive Mitochondrial Proton Leak in Mouse Pancreatic β-Cells.

Aharoni-Simon M, Shumiatcher R, Yeung A, Shih AZ, Dolinsky VW, Doucette CA, Luciani DS.

Endocrinology. 2016 Jun;157(6):2270-81. doi: 10.1210/en.2015-1964. Epub 2016 Apr 12.


Exploring the role of the HNF-1αG319S polymorphism in β cell failure and youth-onset type 2 diabetes: Lessons from MODY and Hnf-1α-deficient animal models.

Jonasson ME, Wicklow BA, Sellers EA, Dolinsky VW, Doucette CA.

Biochem Cell Biol. 2015 Oct;93(5):487-94. doi: 10.1139/bcb-2015-0021. Epub 2015 May 6. Review.


Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome.

Pereira TJ, Fonseca MA, Campbell KE, Moyce BL, Cole LK, Hatch GM, Doucette CA, Klein J, Aliani M, Dolinsky VW.

J Physiol. 2015 Jul 15;593(14):3181-97. doi: 10.1113/JP270429. Epub 2015 Jun 12.

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