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Items: 1 to 20 of 84

1.

Murine Perinatal Beta Cell Proliferation and the Differentiation of Human Stem Cell Derived Insulin Expressing Cells Require NEUROD1.

Romer AI, Singer RA, Sui L, Egli D, Sussel L.

Diabetes. 2019 Sep 13. pii: db190117. doi: 10.2337/db19-0117. [Epub ahead of print]

PMID:
31519700
2.

Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells.

Sagi I, De Pinho JC, Zuccaro MV, Atzmon C, Golan-Lev T, Yanuka O, Prosser R, Sadowy A, Perez G, Cabral T, Glaser B, Tsang SH, Goland R, Sauer MV, Lobo R, Benvenisty N, Egli D.

Cell Stem Cell. 2019 Sep 5;25(3):419-432.e9. doi: 10.1016/j.stem.2019.06.013.

PMID:
31491396
3.

Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant.

Nambiar TS, Billon P, Diedenhofen G, Hayward SB, Taglialatela A, Cai K, Huang JW, Leuzzi G, Cuella-Martin R, Palacios A, Gupta A, Egli D, Ciccia A.

Nat Commun. 2019 Jul 30;10(1):3395. doi: 10.1038/s41467-019-11105-z.

4.

Induction of α cell-restricted Gc in dedifferentiating β cells contributes to stress-induced β-cell dysfunction.

Kuo T, Damle M, González BJ, Egli D, Lazar MA, Accili D.

JCI Insight. 2019 May 23;5. pii: 128351. doi: 10.1172/jci.insight.128351.

5.

Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity.

Foo KS, Skowronski AA, Baum D, Firdessa-Fite R, Thams S, Shang L, Creusot RJ, LeDuc CA, Egli D, Leibel RL.

Sci Rep. 2019 Mar 21;9(1):4965. doi: 10.1038/s41598-019-40768-3.

6.

Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development.

Wang L, De Solis AJ, Goffer Y, Birkenbach KE, Engle SE, Tanis R, Levenson JM, Li X, Rausch R, Purohit M, Lee JY, Tan J, De Rosa MC, Doege CA, Aaron HL, Martins GJ, Brüning JC, Egli D, Costa R, Berbari N, Leibel RL, Stratigopoulos G.

JCI Insight. 2019 Feb 7;4(3). pii: 123337. doi: 10.1172/jci.insight.123337. [Epub ahead of print]

7.

NanoMod: a computational tool to detect DNA modifications using Nanopore long-read sequencing data.

Liu Q, Georgieva DC, Egli D, Wang K.

BMC Genomics. 2019 Feb 4;20(Suppl 1):78. doi: 10.1186/s12864-018-5372-8.

8.

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.

Wang P, Karakose E, Liu H, Swartz E, Ackeifi C, Zlatanic V, Wilson J, González BJ, Bender A, Takane KK, Ye L, Harb G, Pagliuca F, Homann D, Egli D, Argmann C, Scott DK, Garcia-Ocaña A, Stewart AF.

Cell Metab. 2019 Mar 5;29(3):638-652.e5. doi: 10.1016/j.cmet.2018.12.005. Epub 2018 Dec 20.

PMID:
30581122
9.

β Cell Replacement after Gene Editing of a Neonatal Diabetes-Causing Mutation at the Insulin Locus.

Ma S, Viola R, Sui L, Cherubini V, Barbetti F, Egli D.

Stem Cell Reports. 2018 Dec 11;11(6):1407-1415. doi: 10.1016/j.stemcr.2018.11.006. Epub 2018 Nov 29.

10.

Pancreatic Beta Cell Differentiation From Human Pluripotent Stem Cells.

Sui L, Leibel RL, Egli D.

Curr Protoc Hum Genet. 2018 Oct;99(1):e68. doi: 10.1002/cphg.68. Epub 2018 Sep 7.

PMID:
30192441
11.

Inter-homologue repair in fertilized human eggs?

Egli D, Zuccaro MV, Kosicki M, Church GM, Bradley A, Jasin M.

Nature. 2018 Aug;560(7717):E5-E7. doi: 10.1038/s41586-018-0379-5. Epub 2018 Aug 8. No abstract available.

PMID:
30089924
12.

Identification and Analysis of Islet Antigen-Specific CD8+ T Cells with T Cell Libraries.

Ogura H, Preston-Hurlburt P, Perdigoto AL, Amodio M, Krishnaswamy S, Clark P, Yu H, Egli D, Fouts A, Steck AK, Herold KC.

J Immunol. 2018 Sep 15;201(6):1662-1670. doi: 10.4049/jimmunol.1800267. Epub 2018 Aug 6.

13.

ILDR2 has a negligible role in hepatic steatosis.

Millings EJ, De Rosa MC, Fleet S, Watanabe K, Rausch R, Egli D, Li G, Leduc CA, Zhang Y, Fischer SG, Leibel RL.

PLoS One. 2018 May 30;13(5):e0197548. doi: 10.1371/journal.pone.0197548. eCollection 2018.

14.

Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.

Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D'Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A.

Transplantation. 2018 Aug;102(8):1223-1229. doi: 10.1097/TP.0000000000002217. Review.

15.

Derivation and characterization of the NIH registry human stem cell line NYSCF101 under defined feeder-free conditions.

Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S.

Stem Cell Res. 2018 May;29:197-201. doi: 10.1016/j.scr.2018.04.017. Epub 2018 Apr 30.

16.

Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions.

Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S.

Stem Cell Res. 2018 May;29:99-102. doi: 10.1016/j.scr.2018.03.017. Epub 2018 Mar 31.

17.

Derivation and characterization of the NYSCFe003-A human embryonic stem cell line.

Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S.

Stem Cell Res. 2017 Dec;25:217-220. doi: 10.1016/j.scr.2017.10.017. Epub 2017 Nov 21.

18.

β-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells.

Sui L, Danzl N, Campbell SR, Viola R, Williams D, Xing Y, Wang Y, Phillips N, Poffenberger G, Johannesson B, Oberholzer J, Powers AC, Leibel RL, Chen X, Sykes M, Egli D.

Diabetes. 2018 Jan;67(1):26-35. doi: 10.2337/db17-0120. Epub 2017 Sep 20.

19.

Tying genetic stability to cell identity.

Georgieva D, Egli D.

Cell Cycle. 2017 Jun 18;16(12):1139-1140. doi: 10.1080/15384101.2017.1324126. No abstract available.

20.

Genomic instability during reprogramming by nuclear transfer is DNA replication dependent.

Chia G, Agudo J, Treff N, Sauer MV, Billing D, Brown BD, Baer R, Egli D.

Nat Cell Biol. 2017 Apr;19(4):282-291. doi: 10.1038/ncb3485. Epub 2017 Mar 6.

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