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Items: 1 to 20 of 102

1.

Pore-forming activity of the Pseudomonas aeruginosa type III secretion system translocon alters the host epigenome.

Dortet L, Lombardi C, Cretin F, Dessen A, Filloux A.

Nat Microbiol. 2018 Mar;3(3):378-386. doi: 10.1038/s41564-018-0109-7. Epub 2018 Feb 5.

2.

Assembly of an atypical α-macroglobulin complex from Pseudomonas aeruginosa.

Zouhir S, Robert-Genthon M, Trindade DM, Job V, Nedeljković M, Breyton C, Ebel C, Attrée I, Dessen A.

Sci Rep. 2018 Jan 11;8(1):527. doi: 10.1038/s41598-017-18083-6.

3.

Molecular architecture of the PBP2-MreC core bacterial cell wall synthesis complex.

Contreras-Martel C, Martins A, Ecobichon C, Trindade DM, Matteï PJ, Hicham S, Hardouin P, Ghachi ME, Boneca IG, Dessen A.

Nat Commun. 2017 Oct 3;8(1):776. doi: 10.1038/s41467-017-00783-2.

4.

New strategies for targeting and treatment of multi-drug resistant Staphylococcus aureus.

Assis LM, Nedeljković M, Dessen A.

Drug Resist Updat. 2017 Mar;31:1-14. doi: 10.1016/j.drup.2017.03.001. Epub 2017 Apr 6. Review.

PMID:
28867240
5.

A Low-Molecular-Weight Alginate Oligosaccharide Disrupts Pseudomonal Microcolony Formation and Enhances Antibiotic Effectiveness.

Pritchard MF, Powell LC, Jack AA, Powell K, Beck K, Florance H, Forton J, Rye PD, Dessen A, Hill KE, Thomas DW.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00762-17. doi: 10.1128/AAC.00762-17. Print 2017 Sep.

6.

OligoG CF-5/20 normalizes cystic fibrosis mucus by chelating calcium.

Ermund A, Recktenwald CV, Skjåk-Braek G, Meiss LN, Onsøyen E, Rye PD, Dessen A, Myrset AH, Hansson GC.

Clin Exp Pharmacol Physiol. 2017 Jun;44(6):639-647. doi: 10.1111/1440-1681.12744.

PMID:
28261854
7.

A novel guluronate oligomer improves intestinal transit and survival in cystic fibrosis mice.

Vitko M, Valerio DM, Rye PD, Onsøyen E, Myrset AH, Dessen A, Drumm ML, Hodges CA.

J Cyst Fibros. 2016 Nov;15(6):745-751. doi: 10.1016/j.jcf.2016.06.005. Epub 2016 Jun 21.

8.

Structural Insights into Protein-Protein Interactions Involved in Bacterial Cell Wall Biogenesis.

Laddomada F, Miyachiro MM, Dessen A.

Antibiotics (Basel). 2016 Apr 28;5(2). pii: E14. doi: 10.3390/antibiotics5020014. Review.

9.

Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited.

Šink R, Kotnik M, Zega A, Barreteau H, Gobec S, Blanot D, Dessen A, Contreras-Martel C.

PLoS One. 2016 Mar 31;11(3):e0152075. doi: 10.1371/journal.pone.0152075. eCollection 2016.

10.

Structural Basis of Lipid Targeting and Destruction by the Type V Secretion System of Pseudomonas aeruginosa.

da Mata Madeira PV, Zouhir S, Basso P, Neves D, Laubier A, Salacha R, Bleves S, Faudry E, Contreras-Martel C, Dessen A.

J Mol Biol. 2016 May 8;428(9 Pt A):1790-803. doi: 10.1016/j.jmb.2016.03.012. Epub 2016 Mar 21.

PMID:
27012424
11.

A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease.

Pritchard MF, Powell LC, Menzies GE, Lewis PD, Hawkins K, Wright C, Doull I, Walsh TR, Onsøyen E, Dessen A, Myrvold R, Rye PD, Myrset AH, Stevens HN, Hodges LA, MacGregor G, Neilly JB, Hill KE, Thomas DW.

Mol Pharm. 2016 Mar 7;13(3):863-72. doi: 10.1021/acs.molpharmaceut.5b00794. Epub 2016 Feb 16.

PMID:
26833139
12.

A structural snapshot of type II pilus formation in Streptococcus pneumoniae.

Shaik MM, Lombardi C, Maragno Trindade D, Fenel D, Schoehn G, Di Guilmi AM, Dessen A.

J Biol Chem. 2015 Sep 11;290(37):22581-92. doi: 10.1074/jbc.M115.647834. Epub 2015 Jul 21.

13.

FtsZ filament capping by MciZ, a developmental regulator of bacterial division.

Bisson-Filho AW, Discola KF, Castellen P, Blasios V, Martins A, Sforça ML, Garcia W, Zeri AC, Erickson HP, Dessen A, Gueiros-Filho FJ.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2130-8. doi: 10.1073/pnas.1414242112. Epub 2015 Apr 6.

14.

Structure of a bacterial α2-macroglobulin reveals mimicry of eukaryotic innate immunity.

Wong SG, Dessen A.

Nat Commun. 2014 Sep 15;5:4917. doi: 10.1038/ncomms5917.

PMID:
25221932
15.

Structural similarity of secretins from type II and type III secretion systems.

Tosi T, Estrozi LF, Job V, Guilvout I, Pugsley AP, Schoehn G, Dessen A.

Structure. 2014 Sep 2;22(9):1348-1355. doi: 10.1016/j.str.2014.07.005. Epub 2014 Aug 21.

16.

Structural basis of pilus anchoring by the ancillary pilin RrgC of Streptococcus pneumoniae.

Shaik MM, Maccagni A, Tourcier G, Di Guilmi AM, Dessen A.

J Biol Chem. 2014 Jun 13;289(24):16988-97. doi: 10.1074/jbc.M114.555854. Epub 2014 Apr 21.

17.

Structural basis for the inhibition of the chromatin repressor BAHD1 by the bacterial nucleomodulin LntA.

Lebreton A, Job V, Ragon M, Le Monnier A, Dessen A, Cossart P, Bierne H.

MBio. 2014 Jan 21;5(1):e00775-13. doi: 10.1128/mBio.00775-13.

18.

Resistance to antibiotics targeted to the bacterial cell wall.

Nikolaidis I, Favini-Stabile S, Dessen A.

Protein Sci. 2014 Mar;23(3):243-59. doi: 10.1002/pro.2414. Epub 2014 Jan 17. Review.

19.

Membrane and chaperone recognition by the major translocator protein PopB of the type III secretion system of Pseudomonas aeruginosa.

Discola KF, Förster A, Boulay F, Simorre JP, Attree I, Dessen A, Job V.

J Biol Chem. 2014 Feb 7;289(6):3591-601. doi: 10.1074/jbc.M113.517920. Epub 2013 Dec 2.

20.

Specificity determinants for lysine incorporation in Staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex.

Ruane KM, Lloyd AJ, Fülöp V, Dowson CG, Barreteau H, Boniface A, Dementin S, Blanot D, Mengin-Lecreulx D, Gobec S, Dessen A, Roper DI.

J Biol Chem. 2013 Nov 15;288(46):33439-48. doi: 10.1074/jbc.M113.508135. Epub 2013 Sep 24.

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