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Med Mal Infect. 2013 Feb;43(2):81-4. doi: 10.1016/j.medmal.2013.01.016. Epub 2013 Feb 28.

[Description of patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit and identification of severity risk factors].

[Article in French]

Author information

1
Unité épidémiologie et biomarqueurs de l'infection, service d'hygiène, épidémiologie et prévention, hospices civils de Lyon, 69437 Lyon cedex 03, France. cecile.payet@univ-lyon1.fr

Abstract

OBJECTIVE:

The authors had for objective to describe patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit (ICU) in a university hospital and to identify risk factors correlated with the severity of the disease.

DESIGN:

A prospective study was conducted in an university hospital during the A(H1N1)pdm09 influenza pandemic. Severe laboratory confirmed cases (admitted to an ICU) were described and compared with non-severe confirmed cases (not admitted to an ICU).

RESULTS:

Sixty-nine patients were included; 36 (52%) were 15 to 44 years of age. Sixteen (23%) cases were defined as severe, ten of these (63%) concerned patients 45 to 64 years of age. The independent factors associated with severity were: a history of heart disease, obesity, and tobacco abuse.

CONCLUSIONS:

This work reinforces the need to identify and protect groups at risk of severe outcomes.

PMID:
23453670
DOI:
10.1016/j.medmal.2013.01.016
[Indexed for MEDLINE]

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