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The following term was not found in PubMed: DermalRx
Page 1
Src protein-tyrosine kinase structure and regulation.
Roskoski R Jr. Roskoski R Jr. Biochem Biophys Res Commun. 2004 Nov 26;324(4):1155-64. doi: 10.1016/j.bbrc.2004.09.171. Biochem Biophys Res Commun. 2004. PMID: 15504335 Review.
Src and Src-family protein kinases are proto-oncogenes that play key roles in cell morphology, motility, proliferation, and survival. v-Src (a viral protein) is encoded by the chicken oncogene of Rous sarcoma virus, and Src (the cellular homologue) is
Src and Src-family protein kinases are proto-oncogenes that play key roles in cell morphology, motility, proliferation, and su
Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors.
Roskoski R Jr. Roskoski R Jr. Pharmacol Res. 2015 Apr;94:9-25. doi: 10.1016/j.phrs.2015.01.003. Epub 2015 Feb 3. Pharmacol Res. 2015. PMID: 25662515 Review.
The chief phosphorylation sites of human Src include an activating pTyr419 that results from phosphorylation in the kinase domain by an adjacent Src molecule and an inhibitory pTyr530 in the regulatory tail that results from phosphorylation by C-terminal Src
The chief phosphorylation sites of human Src include an activating pTyr419 that results from phosphorylation in the kinase domain by …
The (Patho)Biology of SRC Kinase in Platelets and Megakaryocytes.
De Kock L, Freson K. De Kock L, et al. Medicina (Kaunas). 2020 Nov 24;56(12):633. doi: 10.3390/medicina56120633. Medicina (Kaunas). 2020. PMID: 33255186 Free PMC article. Review.
Proto-oncogene tyrosine-protein kinase SRC (SRC), as other members of the SRC family kinases (SFK), plays an important role in regulating signal transduction by different cell surface receptors after changes in the cellular environment. ...Functional platelet …
Proto-oncogene tyrosine-protein kinase SRC (SRC), as other members of the SRC family kinases (SFK), plays an important …
Role of c-Src in Carcinogenesis and Drug Resistance.
Raji L, Tetteh A, Amin ARMR. Raji L, et al. Cancers (Basel). 2023 Dec 20;16(1):32. doi: 10.3390/cancers16010032. Cancers (Basel). 2023. PMID: 38201459 Free PMC article. Review.
The aberrant transformation of normal cells into cancer cells, known as carcinogenesis, is a complex process involving numerous genetic and molecular alterations in response to innate and environmental stimuli. The Src family kinases (SFK) are key components of signaling p …
The aberrant transformation of normal cells into cancer cells, known as carcinogenesis, is a complex process involving numerous genetic and …
Tyrosine Kinase Src Is a Regulatory Factor of Bone Homeostasis.
Matsubara T, Yasuda K, Mizuta K, Kawaue H, Kokabu S. Matsubara T, et al. Int J Mol Sci. 2022 May 14;23(10):5508. doi: 10.3390/ijms23105508. Int J Mol Sci. 2022. PMID: 35628319 Free PMC article. Review.
Src-knockout mice exhibit osteopetrosis. Therefore, Src is a potential target for osteoporosis therapy. ...Thus, it is challenging to develop effective osteoporosis therapies targeting Src. To solve this problem, it is necessary to understand the molecular me
Src-knockout mice exhibit osteopetrosis. Therefore, Src is a potential target for osteoporosis therapy. ...Thus, it is challen
Ca(2+) Signaling and Src Functions in Tumor Cells.
Villalobo A. Villalobo A. Biomolecules. 2023 Dec 3;13(12):1739. doi: 10.3390/biom13121739. Biomolecules. 2023. PMID: 38136610 Free PMC article. Review.
In this review, we consider the interplay of Ca(2+) signaling and the functions of the proto-oncogene non-receptor tyrosine kinase c-Src in tumor cells, and the viral oncogenic variant v-Src in transformed cells. ...Thus, we cover the available information on the ro …
In this review, we consider the interplay of Ca(2+) signaling and the functions of the proto-oncogene non-receptor tyrosine kinase c-Src
Src signaling in cancer invasion.
Guarino M. Guarino M. J Cell Physiol. 2010 Apr;223(1):14-26. doi: 10.1002/jcp.22011. J Cell Physiol. 2010. PMID: 20049846 Review.
Once activated, Src is the starting point for several biochemical cascades that thereby propagate signals generated extracellularly along intracellular interconnected transduction pathways. ...Because increased activity of Src is a frequent occurrence in many types …
Once activated, Src is the starting point for several biochemical cascades that thereby propagate signals generated extracellularly a …
Nuclear Functions of the Tyrosine Kinase Src.
Bagnato G, Leopizzi M, Urciuoli E, Peruzzi B. Bagnato G, et al. Int J Mol Sci. 2020 Apr 11;21(8):2675. doi: 10.3390/ijms21082675. Int J Mol Sci. 2020. PMID: 32290470 Free PMC article. Review.
Src is the representative member of the Src-family kinases (SFKs), a group of tyrosine kinases involved in several cellular processes. ...In particular, we addressed the Src involvement in physiological as well as in pathological conditions, especially in tum
Src is the representative member of the Src-family kinases (SFKs), a group of tyrosine kinases involved in several cellular pr
Activation of human pp60c-src.
Bjorge JD, O'Connor TJ, Fujita DJ. Bjorge JD, et al. Biochem Cell Biol. 1996;74(4):477-84. doi: 10.1139/o96-052. Biochem Cell Biol. 1996. PMID: 8960354 Review.
pp60c-src and the structurally related members of the Src family are non-receptor tyrosine kinases that reside within the cell associated with cell membranes and appear to transduce signals from transmembrane receptors to the cell interior. ...Various cellular stimu …
pp60c-src and the structurally related members of the Src family are non-receptor tyrosine kinases that reside within the cell …
Src kinase inhibitors: promising cancer therapeutics?
Creedon H, Brunton VG. Creedon H, et al. Crit Rev Oncog. 2012;17(2):145-59. doi: 10.1615/critrevoncog.v17.i2.20. Crit Rev Oncog. 2012. PMID: 22471705 Review.
Src is the cellular counterpart of the first identified viral oncogene v-Src. ...Taking this integrated approach will hopefully help to realize the true potential of Src kinase inhibitors....
Src is the cellular counterpart of the first identified viral oncogene v-Src. ...Taking this integrated approach will hopefull
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