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Expert Opin Drug Saf. 2017 Feb;16(2):111-112. doi: 10.1080/14740338.2017.1273347. Epub 2016 Dec 26.

Deprescribing: a new goal focused on the patient.

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a Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia , Universidad Tecnológica de Pereira - Audifarma S.A. Pereira , Colombia , South America.


It is estimated that one-fifth of adult patients are treated with polypharmacy (five or more drugs) and the prevalence of this phenomenon in the elderly is even higher, ranging from 30% to 70%, even reaching 90% in residents of residential aged care facilities. Polypharmacy in the elderly increases the risk of adverse reactions, inappropriate prescriptions, drug interactions, number of hospitalizations, costs, and even death. In a recent systematic review, the authors proposed defining deprescribing as 'the process of withdrawal of inappropriate medication supervised by a health care professional with the goal of managing polypharmacy and improving outcomes'.


Deprescriptions; pharmacoepidemiology; pharmacovigilance; polypharmacy

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