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Items: 1 to 20 of 169


N-linked glycosylation modulates the immunogenicity of recombinant human factor VIII in hemophilia A mice.

Lai JD, Swystun LL, Cartier D, Nesbitt K, Zhang C, Hough C, Dennis JW, Lillicrap D.

Haematologica. 2018 Jul 12. pii: haematol.2018.188219. doi: 10.3324/haematol.2018.188219. [Epub ahead of print]


Novel application of an old technique: the use of external to internal carotid artery transposition in trauma.

Jensen AM, Dennis JW, Allmon JC, Habib JH, Skarupa DJ.

Trauma Surg Acute Care Open. 2018 Apr 25;3(1):e000182. doi: 10.1136/tsaco-2018-000182. eCollection 2018. No abstract available.


The UBR-1 ubiquitin ligase regulates glutamate metabolism to generate coordinated motor pattern in Caenorhabditis elegans.

Chitturi J, Hung W, Rahman AMA, Wu M, Lim MA, Calarco J, Baran R, Huang X, Dennis JW, Zhen M.

PLoS Genet. 2018 Apr 12;14(4):e1007303. doi: 10.1371/journal.pgen.1007303. eCollection 2018 Apr.


Reassessing the utility of CT angiograms in penetrating injuries to the extremities.

Gurien LA, Kerwin AJ, Yorkgitis BK, Renkosik J, Allmon JC, Habib JH, Dennis JW.

Surgery. 2018 Feb;163(2):419-422. doi: 10.1016/j.surg.2017.09.019. Epub 2017 Nov 20.


N-acetylglucosamine: more than a silent partner in insulin resistance.

Hesketh GG, Dennis JW.

Glycobiology. 2017 Jul 1;27(7):595-598. doi: 10.1093/glycob/cwx035.


Genetic code asymmetry supports diversity through experimentation with posttranslational modifications.

Dennis JW.

Curr Opin Chem Biol. 2017 Dec;41:1-11. doi: 10.1016/j.cbpa.2017.08.012. Epub 2017 Sep 15. Review.


The directed migration of gonadal distal tip cells in Caenorhabditis elegans requires NGAT-1, a ß1,4-N-acetylgalactosaminyltransferase enzyme.

Veyhl J, Dunn RJ, Johnston WL, Bennett A, Zhang LW, Dennis JW, Schachter H, Culotti JG.

PLoS One. 2017 Aug 17;12(8):e0183049. doi: 10.1371/journal.pone.0183049. eCollection 2017.


C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility.

Johnston WL, Krizus A, Ramani AK, Dunham W, Youn JY, Fraser AG, Gingras AC, Dennis JW.

BMC Biol. 2017 Jul 17;15(1):61. doi: 10.1186/s12915-017-0398-y.


Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.

Kazazian K, Go C, Wu H, Brashavitskaya O, Xu R, Dennis JW, Gingras AC, Swallow CJ.

Cancer Res. 2017 Jan 15;77(2):434-447. doi: 10.1158/0008-5472.CAN-16-2060. Epub 2016 Nov 21.


Mgat5 modulates the effect of early life stress on adult behavior and physical health in mice.

Feldcamp L, Doucet JS, Pawling J, Fadel MP, Fletcher PJ, Maunder R, Dennis JW, Wong AH.

Behav Brain Res. 2016 Oct 1;312:253-64. doi: 10.1016/j.bbr.2016.06.033. Epub 2016 Jun 18.


PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia.

Banh RS, Iorio C, Marcotte R, Xu Y, Cojocari D, Rahman AA, Pawling J, Zhang W, Sinha A, Rose CM, Isasa M, Zhang S, Wu R, Virtanen C, Hitomi T, Habu T, Sidhu SS, Koizumi A, Wilkins SE, Kislinger T, Gygi SP, Schofield CJ, Dennis JW, Wouters BG, Neel BG.

Nat Cell Biol. 2016 Jul;18(7):803-813. doi: 10.1038/ncb3376. Epub 2016 Jun 20.


Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways.

Ryczko MC, Pawling J, Chen R, Abdel Rahman AM, Yau K, Copeland JK, Zhang C, Surendra A, Guttman DS, Figeys D, Dennis JW.

Sci Rep. 2016 Mar 14;6:23043. doi: 10.1038/srep23043.


Many Light Touches Convey the Message.

Dennis JW.

Trends Biochem Sci. 2015 Nov;40(11):673-686. doi: 10.1016/j.tibs.2015.08.010. Epub 2015 Oct 1. Review.


The galectin lattice at a glance.

Nabi IR, Shankar J, Dennis JW.

J Cell Sci. 2015 Jul 1;128(13):2213-9. doi: 10.1242/jcs.151159. Epub 2015 Jun 19. Review.


Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

So J, Pasculescu A, Dai AY, Williton K, James A, Nguyen V, Creixell P, Schoof EM, Sinclair J, Barrios-Rodiles M, Gu J, Krizus A, Williams R, Olhovsky M, Dennis JW, Wrana JL, Linding R, Jorgensen C, Pawson T, Colwill K.

Sci Signal. 2015 Apr 7;8(371):rs3. doi: 10.1126/scisignal.2005700.


Golgi N-glycan branching N-acetylglucosaminyltransferases I, V and VI promote nutrient uptake and metabolism.

Abdel Rahman AM, Ryczko M, Nakano M, Pawling J, Rodrigues T, Johswich A, Taniguchi N, Dennis JW.

Glycobiology. 2015 Feb;25(2):225-40. doi: 10.1093/glycob/cwu105. Epub 2014 Oct 1.


Targeted metabolomics in cultured cells and tissues by mass spectrometry: method development and validation.

Abdel Rahman AM, Pawling J, Ryczko M, Caudy AA, Dennis JW.

Anal Chim Acta. 2014 Oct 3;845:53-61. doi: 10.1016/j.aca.2014.06.012. Epub 2014 Jun 12.


A novel role for Plk4 in regulating cell spreading and motility.

Rosario CO, Kazazian K, Zih FS, Brashavitskaya O, Haffani Y, Xu RS, George A, Dennis JW, Swallow CJ.

Oncogene. 2015 Jun;34(26):3441-51. doi: 10.1038/onc.2014.275. Epub 2014 Sep 1.


N-glycan remodeling on glucagon receptor is an effector of nutrient sensing by the hexosamine biosynthesis pathway.

Johswich A, Longuet C, Pawling J, Abdel Rahman A, Ryczko M, Drucker DJ, Dennis JW.

J Biol Chem. 2014 Jun 6;289(23):15927-41. doi: 10.1074/jbc.M114.563734. Epub 2014 Apr 17.


The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism.

Soliman MA, Abdel Rahman AM, Lamming DW, Birsoy K, Pawling J, Frigolet ME, Lu H, Fantus IG, Pasculescu A, Zheng Y, Sabatini DM, Dennis JW, Pawson T.

Sci Signal. 2014 Feb 18;7(313):ra17. doi: 10.1126/scisignal.2004785. Erratum in: Sci Signal. 2014 Mar 4;7(315):er2. Lamming, Dudley A [corrected to Lamming, Dudley W].

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