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Page 1
RIFM fragrance ingredient safety assessment, decanoic acid, CAS Registry Number 334-48-5.
Api AM, Belsito D, Biserta S, Botelho D, Bruze M, Burton GA Jr, Buschmann J, Cancellieri MA, Dagli ML, Date M, Dekant W, Deodhar C, Fryer AD, Gadhia S, Jones L, Joshi K, Lapczynski A, Lavelle M, Liebler DC, Na M, O'Brien D, Patel A, Penning TM, Ritacco G, Rodriguez-Ropero F, Romine J, Sadekar N, Salvito D, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y, Tsang S. Api AM, et al. Food Chem Toxicol. 2020 Oct 15;144 Suppl 1:111465. doi: 10.1016/j.fct.2020.111465. Epub 2020 Jul 5. Food Chem Toxicol. 2020. PMID: 32640335 Review.
Based on the existing data, decanoic acid does not present a concern for skin sensitization under the current, declared levels of use. The phototoxicity/photoallergenicity endpoints were evaluated based on UV spectra; decanoic acid is not expected to b …
Based on the existing data, decanoic acid does not present a concern for skin sensitization under the current, declared levels …
Relationship between Dietary Decanoic Acid and Coronary Artery Disease: A Population-Based Cross-Sectional Study.
Wu Z, Yang W, Li M, Li F, Gong R, Wu Y. Wu Z, et al. Nutrients. 2023 Oct 10;15(20):4308. doi: 10.3390/nu15204308. Nutrients. 2023. PMID: 37892384 Free PMC article.
BACKGROUND: Coronary artery disease (CAD) is a cardiovascular disease with significant personal health and socioeconomic consequences. The biological functions of decanoic acid and the pathogenesis of CAD overlap considerably; however, studies exploring their relati …
BACKGROUND: Coronary artery disease (CAD) is a cardiovascular disease with significant personal health and socioeconomic consequences. The b …
Analysis of the Effects of Food Additives on Porphyromonas gingivalis.
Shinohara M, Maetani M, Kitada C, Nishigami Y, Yazawa A, Kamitani S. Shinohara M, et al. Pathogens. 2022 Jan 4;11(1):65. doi: 10.3390/pathogens11010065. Pathogens. 2022. PMID: 35056013 Free PMC article.
The growth of P. gingivalis was inhibited by 5 mM octanoic acid, 1.25 mM decanoic acid, 1.25% acesulfame K, 0.0625% aspartame, 0.03125% saccharin, and 0.625% sucralose. ...Moreover, biofilm formation was inhibited by 10 mM octanoic acid, 10 mM decanoic aci
The growth of P. gingivalis was inhibited by 5 mM octanoic acid, 1.25 mM decanoic acid, 1.25% acesulfame K, 0.0625% aspartame, …
Decanoic Acid Stimulates Autophagy in D. discoideum.
Warren EC, Kramár P, Lloyd-Jones K, Williams RSB. Warren EC, et al. Cells. 2021 Oct 29;10(11):2946. doi: 10.3390/cells10112946. Cells. 2021. PMID: 34831171 Free PMC article.
Here, we utilize this model to analyze a role for MCFAs in regulating autophagy. We show that treatment with decanoic acid but not octanoic acid induces autophagosome formation and modulates autophagic flux in high glucose conditions. To investigate this effect, …
Here, we utilize this model to analyze a role for MCFAs in regulating autophagy. We show that treatment with decanoic acid but …
Effect of decanoic acid and 10-hydroxydecanoic acid on the biotransformation of methyl decanoate to sebacic acid.
Sugiharto YEC, Lee H, Fitriana AD, Lee H, Jeon W, Park K, Ahn J, Lee H. Sugiharto YEC, et al. AMB Express. 2018 May 5;8(1):75. doi: 10.1186/s13568-018-0605-4. AMB Express. 2018. PMID: 29730843 Free PMC article.
However, we observed the accumulation of intermediates (decanoic acid and 10-hydroxydecanoic acid) during the induction period. ...Moreover, about 24-32% reduction in the decanoic acid oxidation was observed in the presence of 0.5-1.5 g/L 10-hydroxydec …
However, we observed the accumulation of intermediates (decanoic acid and 10-hydroxydecanoic acid) during the induction period …
Seizure control by decanoic acid through direct AMPA receptor inhibition.
Chang P, Augustin K, Boddum K, Williams S, Sun M, Terschak JA, Hardege JD, Chen PE, Walker MC, Williams RS. Chang P, et al. Brain. 2016 Feb;139(Pt 2):431-43. doi: 10.1093/brain/awv325. Epub 2015 Nov 25. Brain. 2016. PMID: 26608744 Free PMC article.
The medium chain triglyceride ketogenic diet is an established treatment for drug-resistant epilepsy that increases plasma levels of decanoic acid and ketones. Recently, decanoic acid has been shown to provide seizure control in vivo, yet its mechanism …
The medium chain triglyceride ketogenic diet is an established treatment for drug-resistant epilepsy that increases plasma levels of deca
The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells.
Mett J, Müller U. Mett J, et al. Sci Rep. 2021 Mar 17;11(1):6135. doi: 10.1038/s41598-021-85523-9. Sci Rep. 2021. PMID: 33731759 Free PMC article.
Phosphatidylcholine (PC) containing decanoic acid (10:0) (PC10:0/10:0) reduced the cellular H(2)O(2) release in comparison to solvent, L-alpha-Glycerophosphorylcholine and PC containing the long-chain fatty acid (LCFA) arachidic acid (20:0). ...It did not affect the …
Phosphatidylcholine (PC) containing decanoic acid (10:0) (PC10:0/10:0) reduced the cellular H(2)O(2) release in comparison to …
New insights into the mechanisms of the ketogenic diet.
Boison D. Boison D. Curr Opin Neurol. 2017 Apr;30(2):187-192. doi: 10.1097/WCO.0000000000000432. Curr Opin Neurol. 2017. PMID: 28141738 Free PMC article. Review.
RECENT FINDINGS: Ketogenic diets act through a combination of mechanisms, which are linked to the effects of ketones and glucose restriction, and to interactions with receptors, channels, and metabolic enzymes. Decanoic acid, a component of medium-chain triclyceride …
RECENT FINDINGS: Ketogenic diets act through a combination of mechanisms, which are linked to the effects of ketones and glucose restriction …
Evaluation of a novel water-soluble decanoic acid formulation as a fruit sanitizer.
Jaber N, Al-Remawi M. Jaber N, et al. Int J Food Microbiol. 2023 Mar 2;388:110067. doi: 10.1016/j.ijfoodmicro.2022.110067. Epub 2022 Dec 30. Int J Food Microbiol. 2023. PMID: 36608355
High sugar content in fruits such as black cherry (BC) fruit encourages microbial proliferation. A novel water-soluble decanoic acid (WSDA) was evaluated as a fruit sanitizer and compared with other traditional fruit sanitizers such as ethanol, bleach, or dishwasher …
High sugar content in fruits such as black cherry (BC) fruit encourages microbial proliferation. A novel water-soluble decanoic ac
1,248 results