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TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.
Fiers W, Beyaert R, Boone E, Cornelis S, Declercq W, Decoster E, Denecker G, Depuydt B, De Valck D, De Wilde G, Goossens V, Grooten J, Haegeman G, Heyninck K, Penning L, Plaisance S, Vancompernolle K, Van Criekinge W, Vandenabeele P, Vanden Berghe W, Van de Craen M, Vandevoorde V, Vercammen D. Fiers W, et al. Among authors: de valck d. J Inflamm. 1995-1996;47(1-2):67-75. J Inflamm. 1995. PMID: 8913931 Review.
The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN.
Heyninck K, De Valck D, Vanden Berghe W, Van Criekinge W, Contreras R, Fiers W, Haegeman G, Beyaert R. Heyninck K, et al. Among authors: de valck d. J Cell Biol. 1999 Jun 28;145(7):1471-82. doi: 10.1083/jcb.145.7.1471. J Cell Biol. 1999. PMID: 10385526 Free PMC article.
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