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Items: 1 to 20 of 98

1.

Mechanisms of the Multitasking Endothelial Protein NRG-1 as a Compensatory Factor During Chronic Heart Failure.

De Keulenaer GW, Feyen E, Dugaucquier L, Shakeri H, Shchendrygina A, Belenkov YN, Brink M, Vermeulen Z, Segers VFM.

Circ Heart Fail. 2019 Oct;12(10):e006288. doi: 10.1161/CIRCHEARTFAILURE.119.006288. Epub 2019 Oct 14.

PMID:
31607147
2.

A special case of hypertrophic cardiomyopathy with a differential diagnosis of isolated cardiac amyloidosis or junctophilin type 2 associated cardiomyopathy.

De Bruijn S, Galloo X, De Keulenaer G, Prihadi EA, Brands C, Helbert M.

Acta Clin Belg. 2019 Sep 3:1-8. doi: 10.1080/17843286.2019.1662572. [Epub ahead of print]

PMID:
31478477
3.

Cardiac endothelial cell transcriptome in neonatal, adult, and remodeling hearts.

Vermeulen Z, Mateiu L, Dugaucquier L, De Keulenaer GW, Segers VFM.

Physiol Genomics. 2019 Jun 1;51(6):186-196. doi: 10.1152/physiolgenomics.00002.2019. Epub 2019 Apr 12.

PMID:
30978160
4.

The continuous heart failure spectrum: moving beyond an ejection fraction classification.

Triposkiadis F, Butler J, Abboud FM, Armstrong PW, Adamopoulos S, Atherton JJ, Backs J, Bauersachs J, Burkhoff D, Bonow RO, Chopra VK, de Boer RA, de Windt L, Hamdani N, Hasenfuss G, Heymans S, Hulot JS, Konstam M, Lee RT, Linke WA, Lunde IG, Lyon AR, Maack C, Mann DL, Mebazaa A, Mentz RJ, Nihoyannopoulos P, Papp Z, Parissis J, Pedrazzini T, Rosano G, Rouleau J, Seferovic PM, Shah AM, Starling RC, Tocchetti CG, Trochu JN, Thum T, Zannad F, Brutsaert DL, Segers VF, De Keulenaer GW.

Eur Heart J. 2019 Jul 1;40(26):2155-2163. doi: 10.1093/eurheartj/ehz158.

PMID:
30957868
5.

Epigenetic regulation of intercellular communication in the heart.

Segers VFM, Gevaert AB, Boen JRA, Van Craenenbroeck EM, De Keulenaer GW.

Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1417-H1425. doi: 10.1152/ajpheart.00038.2019. Epub 2019 Apr 5.

PMID:
30951364
6.

Vascular smooth muscle cell contraction and relaxation in the isolated aorta: a critical regulator of large artery compliance.

Leloup AJA, Van Hove CE, De Moudt S, De Meyer GRY, De Keulenaer GW, Fransen P.

Physiol Rep. 2019 Feb;7(4):e13934. doi: 10.14814/phy2.13934.

7.

Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology.

de Boer RA, De Keulenaer G, Bauersachs J, Brutsaert D, Cleland JG, Diez J, Du XJ, Ford P, Heinzel FR, Lipson KE, McDonagh T, Lopez-Andres N, Lunde IG, Lyon AR, Pollesello P, Prasad SK, Tocchetti CG, Mayr M, Sluijter JPG, Thum T, Tschöpe C, Zannad F, Zimmermann WH, Ruschitzka F, Filippatos G, Lindsey ML, Maack C, Heymans S.

Eur J Heart Fail. 2019 Mar;21(3):272-285. doi: 10.1002/ejhf.1406. Epub 2019 Feb 4.

8.

Neuregulin-1 attenuates right ventricular diastolic stiffness in experimental pulmonary hypertension.

Adão R, Mendes-Ferreira P, Maia-Rocha C, Santos-Ribeiro D, Rodrigues PG, Vidal-Meireles A, Monteiro-Pinto C, Pimentel LD, Falcão-Pires I, De Keulenaer GW, Leite-Moreira AF, Brás-Silva C.

Clin Exp Pharmacol Physiol. 2019 Mar;46(3):255-265. doi: 10.1111/1440-1681.13043. Epub 2018 Dec 2.

PMID:
30339273
9.

Treatments targeting inotropy.

Maack C, Eschenhagen T, Hamdani N, Heinzel FR, Lyon AR, Manstein DJ, Metzger J, Papp Z, Tocchetti CG, Yilmaz MB, Anker SD, Balligand JL, Bauersachs J, Brutsaert D, Carrier L, Chlopicki S, Cleland JG, de Boer RA, Dietl A, Fischmeister R, Harjola VP, Heymans S, Hilfiker-Kleiner D, Holzmeister J, de Keulenaer G, Limongelli G, Linke WA, Lund LH, Masip J, Metra M, Mueller C, Pieske B, Ponikowski P, Ristic A, Ruschitzka F, Seferovic PM, Skouri H, Zimmermann WH, Mebazaa A.

Eur Heart J. 2018 Oct 8. doi: 10.1093/eurheartj/ehy600. [Epub ahead of print]

PMID:
30295807
10.

Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology.

Maack C, Lehrke M, Backs J, Heinzel FR, Hulot JS, Marx N, Paulus WJ, Rossignol P, Taegtmeyer H, Bauersachs J, Bayes-Genis A, Brutsaert D, Bugger H, Clarke K, Cosentino F, De Keulenaer G, Dei Cas A, González A, Huelsmann M, Iaccarino G, Lunde IG, Lyon AR, Pollesello P, Rena G, Riksen NP, Rosano G, Staels B, van Laake LW, Wanner C, Farmakis D, Filippatos G, Ruschitzka F, Seferovic P, de Boer RA, Heymans S.

Eur Heart J. 2018 Dec 21;39(48):4243-4254. doi: 10.1093/eurheartj/ehy596. No abstract available.

11.

Update on pathophysiology and preventive strategies of anthracycline-induced cardiotoxicity.

Corremans R, Adão R, De Keulenaer GW, Leite-Moreira AF, Brás-Silva C.

Clin Exp Pharmacol Physiol. 2019 Mar;46(3):204-215. doi: 10.1111/1440-1681.13036. Epub 2018 Oct 30. Review.

PMID:
30244497
12.

Short-Term Angiotensin II Treatment Affects Large Artery Biomechanics and Function in the Absence of Small Artery Alterations in Mice.

Leloup AJA, De Moudt S, Van Hove CE, Dugaucquier L, Vermeulen Z, Segers VFM, De Keulenaer GW, Fransen P.

Front Physiol. 2018 May 16;9:582. doi: 10.3389/fphys.2018.00582. eCollection 2018.

13.

Diabetes-Induced Cardiomyocyte Passive Stiffening Is Caused by Impaired Insulin-Dependent Titin Modification and Can Be Modulated by Neuregulin-1.

Hopf AE, Andresen C, Kötter S, Isić M, Ulrich K, Sahin S, Bongardt S, Röll W, Drove F, Scheerer N, Vandekerckhove L, De Keulenaer GW, Hamdani N, Linke WA, Krüger M.

Circ Res. 2018 Jul 20;123(3):342-355. doi: 10.1161/CIRCRESAHA.117.312166. Epub 2018 May 14.

PMID:
29760016
14.

Long-term impact of a six-month telemedical care programme on mortality, heart failure readmissions and healthcare costs in patients with chronic heart failure.

Frederix I, Vanderlinden L, Verboven AS, Welten M, Wouters D, De Keulenaer G, Ector B, Elegeert I, Troisfontaines P, Weytjens C, Mullens W, Dendale P.

J Telemed Telecare. 2019 Jun;25(5):286-293. doi: 10.1177/1357633X18774632. Epub 2018 May 10.

PMID:
29742959
15.

Cardiac Remodeling: Endothelial Cells Have More to Say Than Just NO.

Segers VFM, Brutsaert DL, De Keulenaer GW.

Front Physiol. 2018 Apr 11;9:382. doi: 10.3389/fphys.2018.00382. eCollection 2018. Review.

16.

Neuregulin-1 attenuates stress-induced vascular senescence.

Shakeri H, Gevaert AB, Schrijvers DM, De Meyer GRY, De Keulenaer GW, Guns PDF, Lemmens K, Segers VF.

Cardiovasc Res. 2018 Jun 1;114(7):1041-1051. doi: 10.1093/cvr/cvy059.

PMID:
29528383
17.

The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology.

van Bilsen M, Patel HC, Bauersachs J, Böhm M, Borggrefe M, Brutsaert D, Coats AJS, de Boer RA, de Keulenaer GW, Filippatos GS, Floras J, Grassi G, Jankowska EA, Kornet L, Lunde IG, Maack C, Mahfoud F, Pollesello P, Ponikowski P, Ruschitzka F, Sabbah HN, Schultz HD, Seferovic P, Slart RHJA, Taggart P, Tocchetti CG, Van Laake LW, Zannad F, Heymans S, Lyon AR.

Eur J Heart Fail. 2017 Nov;19(11):1361-1378. doi: 10.1002/ejhf.921. Epub 2017 Sep 26. Review.

18.

Inhibitory actions of the NRG-1/ErbB4 pathway in macrophages during tissue fibrosis in the heart, skin, and lung.

Vermeulen Z, Hervent AS, Dugaucquier L, Vandekerckhove L, Rombouts M, Beyens M, Schrijvers DM, De Meyer GRY, Maudsley S, De Keulenaer GW, Segers VFM.

Am J Physiol Heart Circ Physiol. 2017 Nov 1;313(5):H934-H945. doi: 10.1152/ajpheart.00206.2017. Epub 2017 Aug 19.

19.

The future of pleiotropic therapy in heart failure. Lessons from the benefits of exercise training on endothelial function.

De Keulenaer GW, Segers VFM, Zannad F, Brutsaert DL.

Eur J Heart Fail. 2017 May;19(5):603-614. doi: 10.1002/ejhf.735. Epub 2017 Jan 19. Review.

20.

A novel set-up for the ex vivo analysis of mechanical properties of mouse aortic segments stretched at physiological pressure and frequency.

Leloup AJ, Van Hove CE, Kurdi A, De Moudt S, Martinet W, De Meyer GR, Schrijvers DM, De Keulenaer GW, Fransen P.

J Physiol. 2016 Nov 1;594(21):6105-6115. doi: 10.1113/JP272623. Epub 2016 Aug 2.

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