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Items: 1 to 20 of 29

1.

Screening the Pathogen Box for Molecules Active against Plasmodium Sexual Stages Using a New Nanoluciferase-Based Transgenic Line of P. berghei Identifies Transmission-Blocking Compounds.

Calit J, Dobrescu I, Gaitán XA, Borges MH, Ramos MS, Eastman RT, Bargieri DY.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01053-18. doi: 10.1128/AAC.01053-18. Print 2018 Nov.

PMID:
30181368
2.

QSAR-Driven Design and Discovery of Novel Compounds With Antiplasmodial and Transmission Blocking Activities.

Lima MNN, Melo-Filho CC, Cassiano GC, Neves BJ, Alves VM, Braga RC, Cravo PVL, Muratov EN, Calit J, Bargieri DY, Costa FTM, Andrade CH.

Front Pharmacol. 2018 Mar 6;9:146. doi: 10.3389/fphar.2018.00146. eCollection 2018.

3.

In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate.

Cravo P, Machado RB, Leite JA, Leda T, Suwanarusk R, Bittencourt N, Albrecht L, Judice C, Lopes SCP, Lacerda MVG, Ferreira MU, Soares IS, Goh YS, Bargieri DY, Nosten F, Russell B, Rénia L, Costa FTM.

Malar J. 2018 Jan 10;17(1):20. doi: 10.1186/s12936-017-2144-x.

4.

Vaccine Containing the Three Allelic Variants of the Plasmodium vivax Circumsporozoite Antigen Induces Protection in Mice after Challenge with a Transgenic Rodent Malaria Parasite.

Gimenez AM, Lima LC, Françoso KS, Denapoli PMA, Panatieri R, Bargieri DY, Thiberge JM, Andolina C, Nosten F, Renia L, Nussenzweig RS, Nussenzweig V, Amino R, Rodrigues MM, Soares IS.

Front Immunol. 2017 Oct 11;8:1275. doi: 10.3389/fimmu.2017.01275. eCollection 2017.

5.

Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes.

Bargieri DY, Thiberge S, Tay CL, Carey AF, Rantz A, Hischen F, Lorthiois A, Straschil U, Singh P, Singh S, Triglia T, Tsuboi T, Cowman A, Chitnis C, Alano P, Baum J, Pradel G, Lavazec C, Ménard R.

Cell Host Microbe. 2016 Nov 9;20(5):618-630. doi: 10.1016/j.chom.2016.10.015.

6.

Apicomplexa-specific tRip facilitates import of exogenous tRNAs into malaria parasites.

Bour T, Mahmoudi N, Kapps D, Thiberge S, Bargieri D, Ménard R, Frugier M.

Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4717-22. doi: 10.1073/pnas.1600476113. Epub 2016 Apr 11.

7.

The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice.

Kalanon M, Bargieri D, Sturm A, Matthews K, Ghosh S, Goodman CD, Thiberge S, Mollard V, McFadden GI, Ménard R, de Koning-Ward TF.

Cell Microbiol. 2016 Mar;18(3):399-412. doi: 10.1111/cmi.12520. Epub 2015 Oct 14.

PMID:
26347246
8.

Immunization with the MAEBL M2 Domain Protects against Lethal Plasmodium yoelii Infection.

Leite JA, Bargieri DY, Carvalho BO, Albrecht L, Lopes SC, Kayano AC, Farias AS, Chia WN, Claser C, Malleret B, Russell B, Castiñeiras C, Santos LM, Brocchi M, Wunderlich G, Soares IS, Rodrigues MM, Rénia L, Costa FT.

Infect Immun. 2015 Oct;83(10):3781-92. doi: 10.1128/IAI.00262-15. Epub 2015 Jul 13.

9.

AMA1-deficient Toxoplasma gondii parasites transiently colonize mice and trigger an innate immune response that leads to long-lasting protective immunity.

Lagal V, Dinis M, Cannella D, Bargieri D, Gonzalez V, Andenmatten N, Meissner M, Tardieux I.

Infect Immun. 2015 Jun;83(6):2475-86. doi: 10.1128/IAI.02606-14. Epub 2015 Apr 6.

10.

Host cell invasion by apicomplexan parasites: the junction conundrum.

Bargieri D, Lagal V, Andenmatten N, Tardieux I, Meissner M, Ménard R.

PLoS Pathog. 2014 Sep 18;10(9):e1004273. doi: 10.1371/journal.ppat.1004273. eCollection 2014 Sep. Review. No abstract available.

11.

Calcium dynamics of Plasmodium berghei sporozoite motility.

Carey AF, Singer M, Bargieri D, Thiberge S, Frischknecht F, Ménard R, Amino R.

Cell Microbiol. 2014 May;16(5):768-83. doi: 10.1111/cmi.12289. Epub 2014 Apr 4.

PMID:
24617597
12.

Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion.

Bargieri DY, Andenmatten N, Lagal V, Thiberge S, Whitelaw JA, Tardieux I, Meissner M, Ménard R.

Nat Commun. 2013;4:2552. doi: 10.1038/ncomms3552.

13.

Immunogenicity of recombinant proteins consisting of Plasmodium vivax circumsporozoite protein allelic variant-derived epitopes fused with Salmonella enterica Serovar Typhimurium flagellin.

Leal MT, Camacho AG, Teixeira LH, Bargieri DY, Soares IS, Tararam CA, Rodrigues MM.

Clin Vaccine Immunol. 2013 Sep;20(9):1418-25. doi: 10.1128/CVI.00312-13. Epub 2013 Jul 17.

14.

Scoring sporozoite motility.

Carey AF, Ménard R, Bargieri DY.

Methods Mol Biol. 2013;923:371-83.

PMID:
22990792
15.

Host cell invasion by apicomplexans: what do we know?

Bargieri D, Lagal V, Tardieux I, Ménard R.

Trends Parasitol. 2012 Apr;28(4):131-5. doi: 10.1016/j.pt.2012.01.005. Epub 2012 Feb 10.

PMID:
22326913
16.

Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa.

Giovannini D, Späth S, Lacroix C, Perazzi A, Bargieri D, Lagal V, Lebugle C, Combe A, Thiberge S, Baldacci P, Tardieux I, Ménard R.

Cell Host Microbe. 2011 Dec 15;10(6):591-602. doi: 10.1016/j.chom.2011.10.012.

17.

TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium.

Camacho AG, Teixeira LH, Bargieri DY, Boscardin SB, Soares IS, Nussenzweig RS, Nussenzweig V, Rodrigues MM.

Mem Inst Oswaldo Cruz. 2011 Aug;106 Suppl 1:167-71.

18.

FLP/FRT-mediated conditional mutagenesis in pre-erythrocytic stages of Plasmodium berghei.

Lacroix C, Giovannini D, Combe A, Bargieri DY, Späth S, Panchal D, Tawk L, Thiberge S, Carvalho TG, Barale JC, Bhanot P, Ménard R.

Nat Protoc. 2011 Aug 25;6(9):1412-28. doi: 10.1038/nprot.2011.363.

PMID:
21886105
19.

The novel putative transporter NPT1 plays a critical role in early stages of Plasmodium berghei sexual development.

Boisson B, Lacroix C, Bischoff E, Gueirard P, Bargieri DY, Franke-Fayard B, Janse CJ, Ménard R, Baldacci P.

Mol Microbiol. 2011 Sep;81(5):1343-57. doi: 10.1111/j.1365-2958.2011.07767.x. Epub 2011 Aug 4.

20.

Malaria Vaccine Development: Are Bacterial Flagellin Fusion Proteins the Bridge between Mouse and Humans?

Bargieri DY, Soares IS, Costa FT, Braga CJ, Ferreira LC, Rodrigues MM.

J Parasitol Res. 2011;2011:965369. doi: 10.1155/2011/965369. Epub 2011 Mar 14.

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