Daines RA[Author] - Search Results

Year	Number of Results
1993	3
1994	1
1995	1
1996	1
1999	1
2001	2
2003	2
2005	1
2024	0

1

Bacterial beta-ketoacyl-acyl carrier protein synthases as targets for antibacterial agents.

Khandekar SS, Daines RA, Lonsdale JT. Khandekar SS, et al. Among authors: daines ra. Curr Protein Pept Sci. 2003 Feb;4(1):21-9. doi: 10.2174/1389203033380377. Curr Protein Pept Sci. 2003. PMID: 12570782 Review.

2

Synthesis of structural analogs of leukotriene B4 and their receptor binding activity.

Kingsbury WD, Pendrak I, Leber JD, Boehm JC, Mallet B, Sarau HM, Foley JJ, Schmidt DB, Daines RA. Kingsbury WD, et al. Among authors: daines ra. J Med Chem. 1993 Oct 29;36(22):3308-20. doi: 10.1021/jm00074a012. J Med Chem. 1993. PMID: 8230121

3

Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist.

Aiyar N, Daines RA, Disa J, Chambers PA, Sauermelch CF, Quiniou M, Khandoudi N, Gout B, Douglas SA, Willette RN. Aiyar N, et al. Among authors: daines ra. J Pharmacol Exp Ther. 2001 Mar;296(3):768-75. J Pharmacol Exp Ther. 2001. PMID: 11181905

4

Identification, substrate specificity, and inhibition of the Streptococcus pneumoniae beta-ketoacyl-acyl carrier protein synthase III (FabH).

Khandekar SS, Gentry DR, Van Aller GS, Warren P, Xiang H, Silverman C, Doyle ML, Chambers PA, Konstantinidis AK, Brandt M, Daines RA, Lonsdale JT. Khandekar SS, et al. Among authors: daines ra. J Biol Chem. 2001 Aug 10;276(32):30024-30. doi: 10.1074/jbc.M101769200. Epub 2001 May 24. J Biol Chem. 2001. PMID: 11375394 Free article.

5

First X-ray cocrystal structure of a bacterial FabH condensing enzyme and a small molecule inhibitor achieved using rational design and homology modeling.

Daines RA, Pendrak I, Sham K, Van Aller GS, Konstantinidis AK, Lonsdale JT, Janson CA, Qiu X, Brandt M, Khandekar SS, Silverman C, Head MS. Daines RA, et al. J Med Chem. 2003 Jan 2;46(1):5-8. doi: 10.1021/jm025571b. J Med Chem. 2003. PMID: 12502353

6

Crystal structure and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus.

Qiu X, Choudhry AE, Janson CA, Grooms M, Daines RA, Lonsdale JT, Khandekar SS. Qiu X, et al. Among authors: daines ra. Protein Sci. 2005 Aug;14(8):2087-94. doi: 10.1110/ps.051501605. Epub 2005 Jun 29. Protein Sci. 2005. PMID: 15987898 Free PMC article.

7

In vitro and in vivo pharmacological characterization of SB 201993, an eicosanoid-like LTB4 receptor antagonist with anti-inflammatory activity.

Sarau HM, Foley JJ, Schmidt DB, Martin LD, Webb EF, Tzimas MN, Breton JJ, Chabot-Fletcher M, Underwood DC, Hay DW, Kingsbury WD, Chambers PA, Pendrak I, Jakas DR, Sathe GM, Van Horn S, Daines RA, Griswold DE. Sarau HM, et al. Among authors: daines ra. Prostaglandins Leukot Essent Fatty Acids. 1999 Jul;61(1):55-64. doi: 10.1054/plef.1999.0074. Prostaglandins Leukot Essent Fatty Acids. 1999. PMID: 10477044

8

(E)-3-[[[[6-(2-carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]-methyl]thio]methyl]benzoic acid and related compounds: high affinity leukotriene B4 receptor antagonists.

Daines RA, Chambers PA, Eggleston DS, Foley JJ, Griswold DE, Haltiwanger RC, Jakas DR, Kingsbury WD, Martin LD, Pendrak I, et al. Daines RA, et al. J Med Chem. 1994 Sep 30;37(20):3327-36. doi: 10.1021/jm00046a017. J Med Chem. 1994. PMID: 7932560

9

SB 209247, a high affinity LTB4 receptor antagonist demonstrating potent antiinflammatory activity.

Sarau HM, Foley JJ, Schmidt DB, Tzimas MN, Martin LD, Daines RA, Chambers PA, Kingsbury WD, Griswold DE. Sarau HM, et al. Among authors: daines ra. Adv Prostaglandin Thromboxane Leukot Res. 1995;23:275-7. Adv Prostaglandin Thromboxane Leukot Res. 1995. PMID: 7732852 No abstract available.

10

(E)-3-[6-[[(2,6-dichlorophenyl)thio]methyl]-3-(2-phenylethoxy)-2- pyridinyl]-2-propenoic acid: a high-affinity leukotriene B4 receptor antagonist with oral antiinflammatory activity.

Daines RA, Chambers PA, Foley JJ, Griswold DE, Kingsbury WD, Martin LD, Schmidt DB, Sham KK, Sarau HM. Daines RA, et al. J Med Chem. 1996 Sep 13;39(19):3837-41. doi: 10.1021/jm960248s. J Med Chem. 1996. PMID: 8809171

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