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Items: 8


"Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300".

Borzì RM, Cetrullo S, D'Adamo S, Minguzzi M, Flamigni F.

Exp Mol Med. 2019 Mar 1;51(3):25. doi: 10.1038/s12276-019-0224-4. No abstract available.


Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis.

Minguzzi M, Cetrullo S, D'Adamo S, Silvestri Y, Flamigni F, Borzì RM.

Oxid Med Cell Longev. 2018 Feb 11;2018:3075293. doi: 10.1155/2018/3075293. eCollection 2018. Review.


MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis.

D'Adamo S, Cetrullo S, Minguzzi M, Silvestri Y, Borzì RM, Flamigni F.

Oxid Med Cell Longev. 2017;2017:3720128. doi: 10.1155/2017/3720128. Epub 2017 Jun 21. Review.


Hydroxytyrosol prevents chondrocyte death under oxidative stress by inducing autophagy through sirtuin 1-dependent and -independent mechanisms.

Cetrullo S, D'Adamo S, Guidotti S, Borzì RM, Flamigni F.

Biochim Biophys Acta. 2016 Jun;1860(6):1181-91. doi: 10.1016/j.bbagen.2016.03.002. Epub 2016 Mar 3.


mTOR, AMPK, and Sirt1: Key Players in Metabolic Stress Management.

Cetrullo S, D'Adamo S, Tantini B, Borzi RM, Flamigni F.

Crit Rev Eukaryot Gene Expr. 2015;25(1):59-75. Review.


Hydroxytyrosol prevents increase of osteoarthritis markers in human chondrocytes treated with hydrogen peroxide or growth-related oncogene α.

Facchini A, Cetrullo S, D'Adamo S, Guidotti S, Minguzzi M, Facchini A, Borzì RM, Flamigni F.

PLoS One. 2014 Oct 3;9(10):e109724. doi: 10.1371/journal.pone.0109724. eCollection 2014.


Polyamine delivery as a tool to modulate stem cell differentiation in skeletal tissue engineering.

Borzì RM, Guidotti S, Minguzzi M, Facchini A, Platano D, Trisolino G, Filardo G, Cetrullo S, D'Adamo S, Stefanelli C, Facchini A, Flamigni F.

Amino Acids. 2014 Mar;46(3):717-28. doi: 10.1007/s00726-013-1607-9. Epub 2013 Nov 19. Review.


Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma.

Giovannini C, Baglioni M, Baron Toaldo M, Ventrucci C, D'Adamo S, Cipone M, Chieco P, Gramantieri L, Bolondi L.

Oncotarget. 2013 Oct;4(10):1618-31.

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