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Items: 1 to 20 of 622

1.

Optimization of structures, biochemical properties of ketorolac and its degradation products based on computational studies.

Uzzaman M, Uddin MN.

Daru. 2019 Feb 19. doi: 10.1007/s40199-019-00243-w. [Epub ahead of print]

PMID:
30784007
2.

Antipyretic effect of phytol, possibly via 5KIR-dependent COX-2 inhibition pathway.

Islam MT.

Inflammopharmacology. 2019 Feb 18. doi: 10.1007/s10787-019-00574-9. [Epub ahead of print]

PMID:
30778877
3.

Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.

AlFadly ED, Elzahhar PA, Tramarin A, Elkazaz S, Shaltout H, Abu-Serie MM, Janockova J, Soukup O, Ghareeb DA, El-Yazbi AF, Rafeh RW, Bakkar NZ, Kobeissy F, Iriepa I, Moraleda I, Saudi MNS, Bartolini M, Belal ASF.

Eur J Med Chem. 2019 Feb 8;167:161-186. doi: 10.1016/j.ejmech.2019.02.012. [Epub ahead of print]

PMID:
30771604
4.

Discovery, synthesis and molecular corroborations of medicinally important novel pyrazoles; drug efficacy determinations through in silico, in vitro and cytotoxicity validations.

Thangarasu P, Manikandan A, Thamaraiselvi S.

Bioorg Chem. 2019 Feb 7;86:410-419. doi: 10.1016/j.bioorg.2019.02.003. [Epub ahead of print]

PMID:
30769266
5.

Forsythiaside prevents β-amyloid-induced hippocampal slice injury by upregulating 2-arachidonoylglycerol via cannabinoid receptor 1-dependent NF-κB pathway.

Chen L, Yan Y, Chen T, Zhang L, Gao X, Du C, Du H.

Neurochem Int. 2019 Feb 13;125:57-66. doi: 10.1016/j.neuint.2019.02.008. [Epub ahead of print]

PMID:
30769029
6.

Design, synthesis and biological evaluation of amide-pyridine derivatives as novel dual-target (SE, CYP51) antifungal inhibitors.

Sun B, Dong Y, Lei K, Wang J, Zhao L, Liu M.

Bioorg Med Chem. 2019 Feb 5. pii: S0968-0896(18)32111-4. doi: 10.1016/j.bmc.2019.02.009. [Epub ahead of print]

PMID:
30765301
7.

Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds.

Atatreh N, Youssef AM, Ghattas MA, Al Sorkhy M, Alrawashdeh S, Al-Harbi KB, El-Ashmawy IM, Almundarij TI, Abdelghani AA, Abd-El-Aziz AS.

Bioorg Chem. 2019 Feb 5;86:393-400. doi: 10.1016/j.bioorg.2019.02.014. [Epub ahead of print]

PMID:
30763886
8.

Beta-Cryptoxanthin Inhibits Lipopolysaccharide-Induced Osteoclast Differentiation and Bone Resorption via the Suppression of Inhibitor of NF-κB Kinase Activity.

Hirata N, Ichimaru R, Tominari T, Matsumoto C, Watanabe K, Taniguchi K, Hirata M, Ma S, Suzuki K, Grundler FMW, Miyaura C, Inada M.

Nutrients. 2019 Feb 10;11(2). pii: E368. doi: 10.3390/nu11020368.

9.

Screening of anti-inflammatory phytocompounds from Crateva adansonii leaf extracts and its validation by in silico modeling.

Thirumalaisamy R, Ammashi S, Muthusamy G.

J Genet Eng Biotechnol. 2018 Dec;16(2):711-719. doi: 10.1016/j.jgeb.2018.03.004. Epub 2018 Mar 23.

10.

Design and Synthesis of Triazole-Phthalimide Hybrids with Anti-inflammatory Activity.

Assis SPO, Silva MTD, Silva FTD, Sant'Anna MP, Tenório CMBA, Santos CFBD, Fonseca CSMD, Seabra G, Lima VLM, Oliveira RN.

Chem Pharm Bull (Tokyo). 2019;67(2):96-105. doi: 10.1248/cpb.c18-00607.

11.

Imidazolo and tryptophan-imidazolo hybrid derived ureas/thioureas as potent bioactive agents - SAR and molecular modelling studies.

Kumara HK, Suhas R, Suyoga Vardhan DM, Shobha M, Channe Gowda D.

Bioorg Chem. 2019 Jan 18;86:34-38. doi: 10.1016/j.bioorg.2019.01.027. [Epub ahead of print]

PMID:
30684861
12.

Synthesis, spectroscopic characterization, molecular docking and theoretical studies (DFT) of N-(4-aminophenylsulfonyl)-2-(4-isobutylphenyl) propanamide having potential enzyme inhibition applications.

Asghar A, Yousuf M, Mubeen H, Nazir R, Haruna K, Onawole AT, Rasheed L.

Bioorg Med Chem. 2019 Jan 17. pii: S0968-0896(18)31649-3. doi: 10.1016/j.bmc.2019.01.012. [Epub ahead of print]

PMID:
30683553
13.

The in silico and in vivo evaluation of puerarin against Alzheimer's disease.

Liu S, Cao XL, Liu GQ, Zhou T, Yang XL, Ma BX.

Food Funct. 2019 Feb 20;10(2):799-813. doi: 10.1039/c8fo01696h.

PMID:
30675620
14.

The phytochemical and anti-inflammatory studies of Dillenia suffruticosa leaves.

Abubakar S, Al-Mansoub MA, Murugaiyah V, Chan KL.

Phytother Res. 2019 Jan 17. doi: 10.1002/ptr.6255. [Epub ahead of print]

PMID:
30653753
15.

[Vitamin and antioxidant properties of tocopherols: characteristic of the molecular mechanisms of action].

Sarkisyan VA, Kodentsova VM, Bessonov VV, Kochetkova AA.

Vopr Pitan. 2018;87(3):5-11. doi: 10.24411/0042-8833-2018-10025. Epub 2018 May 11. Russian.

PMID:
30592875
16.

Research Advances and Prospects on Mechanism of Sinomenin on Histamine Release and the Binding to Histamine Receptors.

Zhang YS, Han JY, Iqbal O, Liang AH.

Int J Mol Sci. 2018 Dec 24;20(1). pii: E70. doi: 10.3390/ijms20010070. Review.

17.

Design, synthesis, and biological evaluation of new pyrazino[1,2-a]benzimidazole derivatives as selective cyclooxygenase (COX-2) inhibitors.

Azami Movahed M, Daraei B, Shahosseini S, Esfahanizadeh M, Zarghi A.

Arch Pharm (Weinheim). 2019 Feb;352(2):e1800265. doi: 10.1002/ardp.201800265. Epub 2018 Dec 18.

PMID:
30561073
19.

Synthesis, characterization, molecular docking, analgesic, antiplatelet and anticoagulant effects of dibenzylidene ketone derivatives.

Ahmed T, Khan AU, Abbass M, Filho ER, Ud Din Z, Khan A.

Chem Cent J. 2018 Dec 6;12(1):134. doi: 10.1186/s13065-018-0507-1.

20.

Anti-inflammatory indomethacin analogs endowed with preferential COX-2 inhibitory activity.

Amin NH, El-Saadi MT, Hefny AA, Abdelazeem AH, Elshemy HA, Abdellatif KR.

Future Med Chem. 2018 Dec 6. doi: 10.4155/fmc-2018-0224. [Epub ahead of print]

PMID:
30518260

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