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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
2001 4
2002 3
2003 6
2004 6
2005 19
2006 5
2007 9
2008 8
2009 7
2010 14
2011 12
2012 13
2013 9
2014 11
2015 10
2016 8
2017 3
2018 11
2019 10
2020 4
2021 7
2022 4
2023 4
2024 0

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166 results

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Page 1
Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.
Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Canales JR, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, Fan Y, Peyton M, Girard L, Coombes KR, Toniatti C, Heffernan TP, Choi M, Frampton GM, Miller V, Weinstein JN, Herbst RS, Wong KK, Zhang J, Sharma P, Mills GB, Hong WK, Minna JD, Allison JP, Futreal A, Wang J, Wistuba II, Heymach JV. Skoulidis F, et al. Among authors: coombes kr. Cancer Discov. 2015 Aug;5(8):860-77. doi: 10.1158/2159-8290.CD-14-1236. Epub 2015 Jun 11. Cancer Discov. 2015. PMID: 26069186 Free PMC article.
A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition.
Mak MP, Tong P, Diao L, Cardnell RJ, Gibbons DL, William WN, Skoulidis F, Parra ER, Rodriguez-Canales J, Wistuba II, Heymach JV, Weinstein JN, Coombes KR, Wang J, Byers LA. Mak MP, et al. Among authors: coombes kr. Clin Cancer Res. 2016 Feb 1;22(3):609-20. doi: 10.1158/1078-0432.CCR-15-0876. Epub 2015 Sep 29. Clin Cancer Res. 2016. PMID: 26420858 Free PMC article.
Intratumoral Heterogeneity and Clonal Evolution Induced by HPV Integration.
Akagi K, Symer DE, Mahmoud M, Jiang B, Goodwin S, Wangsa D, Li Z, Xiao W, Dunn JD, Ried T, Coombes KR, Sedlazeck FJ, Gillison ML. Akagi K, et al. Among authors: coombes kr. Cancer Discov. 2023 Apr 3;13(4):910-927. doi: 10.1158/2159-8290.CD-22-0900. Cancer Discov. 2023. PMID: 36715691 Free PMC article.
Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang Q, Stachelscheid J, Bloehdorn J, Pacholewska A, Aszyk C, Grotenhuijs F, Müller T, Onder O, Wagle P, Herling CD, Kleppe M, Wang Z, Coombes KR, Robrecht S, Dalvi PS, Plosnita B, Mayer P, Abruzzo LV, Altmüller J, Gathof B, Persigehl T, Fischer K, Jebaraj B, Rienhoff HY, Ecker R, Zhao Y, Bruns CJ, Stilgenbauer S, Elenitoba-Johnson K, Hallek M, Schweiger MR, Odenthal M, Vasyutina E, Herling M. Jiang Q, et al. Among authors: coombes kr. Blood. 2023 Jul 6;142(1):44-61. doi: 10.1182/blood.2022017230. Blood. 2023. PMID: 37023372
An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV. Byers LA, et al. Among authors: coombes kr. Clin Cancer Res. 2013 Jan 1;19(1):279-90. doi: 10.1158/1078-0432.CCR-12-1558. Epub 2012 Oct 22. Clin Cancer Res. 2013. PMID: 23091115 Free PMC article.
Explaining Gene Expression Using Twenty-One MicroRNAs.
Asiaee A, Abrams ZB, Nakayiza S, Sampath D, Coombes KR. Asiaee A, et al. Among authors: coombes kr. J Comput Biol. 2020 Jul;27(7):1157-1170. doi: 10.1089/cmb.2019.0321. Epub 2019 Dec 2. J Comput Biol. 2020. PMID: 31794247 Free PMC article.
Simulation-derived best practices for clustering clinical data.
Coombes CE, Liu X, Abrams ZB, Coombes KR, Brock G. Coombes CE, et al. Among authors: coombes kr. J Biomed Inform. 2021 Jun;118:103788. doi: 10.1016/j.jbi.2021.103788. Epub 2021 Apr 20. J Biomed Inform. 2021. PMID: 33862229 Free PMC article.
Proteogenomic Analysis of Surgically Resected Lung Adenocarcinoma.
Sharpnack MF, Ranbaduge N, Srivastava A, Cerciello F, Codreanu SG, Liebler DC, Mascaux C, Miles WO, Morris R, McDermott JE, Sharpnack JL, Amann J, Maher CA, Machiraju R, Wysocki VH, Govindan R, Mallick P, Coombes KR, Huang K, Carbone DP. Sharpnack MF, et al. Among authors: coombes kr. J Thorac Oncol. 2018 Oct;13(10):1519-1529. doi: 10.1016/j.jtho.2018.06.025. Epub 2018 Jul 11. J Thorac Oncol. 2018. PMID: 30017829 Free PMC article.
166 results