Construction of collagen gel scaffolds for mechanical stress analysis.
Biosci Biotechnol Biochem. 2014.
PMID: 25036833
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Construction of collagen gel scaffolds for mechanical stress analysis.
Biosci Biotechnol Biochem. 2014;78(3):458-61. doi: 10.1080/09168451.2014.882749. Epub 2014 Apr 16.
Biosci Biotechnol Biochem. 2014.
PMID: 25036833
We designed a cyclic compression system using readily available six-well culture plates to investigate the influence of mechanical stress on skin-like structures. The effects of cyclic mechanical stress on protein expression by cells were easily examin …
We designed a cyclic compression system using readily available six-well culture plates to investigate the influence of mechanical …
Mechanical interactions of mouse mammary gland cells with collagen in a three-dimensional construct.
Ann Biomed Eng. 2010 Aug;38(8):2485-98. doi: 10.1007/s10439-010-0015-5. Epub 2010 Apr 22.
Ann Biomed Eng. 2010.
PMID: 20411334
To ensure physiologically relevant materials properties for analysis, the collagen was characterized using independent tensile testing with strain rates in the range of those measured in the cell-gel constructs. 3D elastic theory for an isotropic mater …
To ensure physiologically relevant materials properties for analysis, the collagen was characterized using independent tensile …
Design and fabrication of anatomical bioreactor systems containing alginate scaffolds for cartilage tissue engineering.
Avicenna J Med Biotechnol. 2012 Apr;4(2):65-74.
Avicenna J Med Biotechnol. 2012.
PMID: 23408660
Free PMC article.
The dynamic mechanical device applied a linear mechanical displacement of 2 mm to 10 mm. The CFD modeling indicated peak velocity and maximum wall shear stress were 1.70610(-3)m/s and 0.02407 dyne/cm(2), respectively. Histochemical and immunohistochemical …
The dynamic mechanical device applied a linear mechanical displacement of 2 mm to 10 mm. The CFD modeling indicated peak veloc …
Real time responses of fibroblasts to plastically compressed fibrillar collagen hydrogels.
Biomaterials. 2011 Jul;32(21):4761-72. doi: 10.1016/j.biomaterials.2011.03.043. Epub 2011 Apr 22.
Biomaterials. 2011.
PMID: 21514662
Plastic compression (PC) is a simple and reproducible approach for the immediate production of dense fibrillar collagen (DC) scaffolds which demonstrate multiple improvements for tissue engineered constructs including extracellular matrix (ECM)-like meso scal …
Plastic compression (PC) is a simple and reproducible approach for the immediate production of dense fibrillar collagen (DC) scaff …
A dual-phase scaffold produced by rotary jet spinning and electrospinning for tendon tissue engineering.
Biomed Mater. 2020 Oct 3;15(6):065014. doi: 10.1088/1748-605X/ab9550.
Biomed Mater. 2020.
PMID: 32438362
GDF-5 treatment improved the viability, collagen type III deposition and scaffold penetration of human adipose derived stem cells. The developed FSPCL/ESPCL-Gel 3:1 scaffold (FS = centrifugal force spinning/RJS, ES = wet electrospinning, Gel = g …
GDF-5 treatment improved the viability, collagen type III deposition and scaffold penetration of human adipose derived stem ce …
Human umbilical cord cells for cardiovascular tissue engineering: a comparative study.
Eur J Cardiothorac Surg. 2004 Apr;25(4):635-41. doi: 10.1016/j.ejcts.2003.12.038.
Eur J Cardiothorac Surg. 2004.
PMID: 15037283
Free article.
Isolated cells were characterized by flow cytometry, histology, immunohistochemistry, proliferation assays and compared to VC. Morphological analysis of the seeded polymer strips included histology, immunohistochemistry, sodium dodecyl sulfate-polyacrylamide gel ele …
Isolated cells were characterized by flow cytometry, histology, immunohistochemistry, proliferation assays and compared to VC. Morphological …
Computational modeling of multicellular constructs with the material point method.
J Biomech. 2006;39(11):2074-86. doi: 10.1016/j.jbiomech.2005.06.017. Epub 2005 Aug 10.
J Biomech. 2006.
PMID: 16095601
The standard implicit time integration algorithm for MPM was modified to allow the background computational grid to remain fixed with respect to the spatial distribution of material points during the analysis. This algorithm was used to simulate the 3D mechanics of a vascu …
The standard implicit time integration algorithm for MPM was modified to allow the background computational grid to remain fixed with respec …
Dynamic deformational loading results in selective application of mechanical stimulation in a layered, tissue-engineered cartilage construct.
Biorheology. 2006;43(3,4):497-507.
Biorheology. 2006.
PMID: 16912421
The application of dynamic physiologic loading to a bilayered chondrocyte-seeded agarose construct with a 2% (wt/vol) top layer and 3% (wt/vol) bottom layer was hypothesized to (1) improve overall construct properties and (2) result in a tissue that mimics the me …
The application of dynamic physiologic loading to a bilayered chondrocyte-seeded agarose construct with a 2% (wt/vol) top layer and 3 …
Engineering three-dimensional constructs of the periodontal ligament in hyaluronan-gelatin hydrogel films and a mechanically active environment.
J Periodontal Res. 2013 Dec;48(6):790-801. doi: 10.1111/jre.12072. Epub 2013 Apr 15.
J Periodontal Res. 2013.
PMID: 23581542
Our aim therefore was to engineer and characterize three-dimensional constructs, by seeding PDL cells into hyaluronan-gelatin hydrogel films (80-100 mum) in a format capable of being mechanically deformed. ...CTGF/FGF-2 stimulated cell proliferation in stationary cultures, …
Our aim therefore was to engineer and characterize three-dimensional constructs, by seeding PDL cells into hyaluronan-gelatin hydroge …
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