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370 results

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Page 1
Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial.
Delany-Moretlwe S, Hughes JP, Bock P, Ouma SG, Hunidzarira P, Kalonji D, Kayange N, Makhema J, Mandima P, Mathew C, Spooner E, Mpendo J, Mukwekwerere P, Mgodi N, Ntege PN, Nair G, Nakabiito C, Nuwagaba-Biribonwoha H, Panchia R, Singh N, Siziba B, Farrior J, Rose S, Anderson PL, Eshleman SH, Marzinke MA, Hendrix CW, Beigel-Orme S, Hosek S, Tolley E, Sista N, Adeyeye A, Rooney JF, Rinehart A, Spreen WR, Smith K, Hanscom B, Cohen MS, Hosseinipour MC; HPTN 084 study group. Delany-Moretlwe S, et al. Lancet. 2022 May 7;399(10337):1779-1789. doi: 10.1016/S0140-6736(22)00538-4. Epub 2022 Apr 1. Lancet. 2022. PMID: 35378077 Free PMC article. Clinical Trial.
Participants were eligible for enrolment if they were assigned female sex at birth, were aged 18-45 years, reported at least two episodes of vaginal intercourse in the previous 30 days, were at risk of HIV infection based on an HIV risk score, and agreed to use a long-acti …
Participants were eligible for enrolment if they were assigned female sex at birth, were aged 18-45 years, reported at least two episodes of …
Immunodeficiency.
Justiz Vaillant AA, Qurie A. Justiz Vaillant AA, et al. 2023 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29763203 Free Books & Documents.
Treatment should not include gammaglobulin preparations to prevent hypersensitivity reactions. . T-cell Immunodeficiencies Congenital thymic aplasia (DiGeorge syndrome): Tetany is present. Fungal and viral infections are common. ...There are decreased responses to a …
Treatment should not include gammaglobulin preparations to prevent hypersensitivity reactions. . T-cell Immunodeficiencies Congenital
Congenital toxoplasmosis infection in an infant born to an HIV-1-infected mother.
Cruz ML, Cardoso CA, Saavedra MC, Santos ED, Melino T. Cruz ML, et al. Braz J Infect Dis. 2007 Dec;11(6):610-1. doi: 10.1590/s1413-86702007000600017. Braz J Infect Dis. 2007. PMID: 18327477 Review.
We report the occurrence of congenital toxoplasmosis in an infant born to an HIV infected mother who had high anti-toxoplasma IgG and negative IgM at nine weeks of gestation. We briefly review available literature and discuss the possible mechanisms of transmission …
We report the occurrence of congenital toxoplasmosis in an infant born to an HIV infected mother who had high anti-toxoplasma …
Paediatric HIV-1 infection: updated strategies of prevention mother-to-child transmission.
Lumaca A, Galli L, de Martino M, Chiappini E. Lumaca A, et al. J Chemother. 2018 Jul;30(4):193-202. doi: 10.1080/1120009X.2018.1451030. Epub 2018 Mar 29. J Chemother. 2018. PMID: 29595094 Review.
INTRODUCTION: HIV-1 epidemiology is changing and prevention of mother-to-child transmission (PMTCT) strategies have been continuously optimized over time. However, the correct management of infected women during pregnancy is crucial for PMTCT and cases of ver …
INTRODUCTION: HIV-1 epidemiology is changing and prevention of mother-to-child transmission (PMTCT) strategies have been conti …
Maternal Antibody Responses and Nonprimary Congenital Cytomegalovirus Infection of HIV-1-Exposed Infants.
Bialas KM, Westreich D, Cisneros de la Rosa E, Nelson CS, Kauvar LM, Fu TM, Permar SR. Bialas KM, et al. J Infect Dis. 2016 Dec 15;214(12):1916-1923. doi: 10.1093/infdis/jiw487. Epub 2016 Oct 20. J Infect Dis. 2016. PMID: 27923951 Free PMC article.
Risk of congenital cytomegalovirus (cCMV) transmission is highly dependent on the presence of preexisting maternal immunity, with the lowest rates observed in CMV-seroimmune populations. Among infants of CMV-seroimmune women, those who are exposed to human immunodeficiency …
Risk of congenital cytomegalovirus (cCMV) transmission is highly dependent on the presence of preexisting maternal immunity, with the …
Mother-to-child transmission of HIV-1.
Jacquez JA. Jacquez JA. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Dec 1;16(4):284-92. doi: 10.1097/00042560-199712010-00010. J Acquir Immune Defic Syndr Hum Retrovirol. 1997. PMID: 9402076 Review.
Through use of transmission data on women in the primary stage of infection, the probability of HIV transmission during pregnancy was calculated as a function of the time pregnancy starts in relation to the stage of infection. Also calculated was the conditional pro …
Through use of transmission data on women in the primary stage of infection, the probability of HIV transmission during pregnancy was …
Neurological manifestations of perinatally acquired HIV-1 infection.
Epstein LG, Sharer LR. Epstein LG, et al. Semin Pediatr Neurol. 1994 Sep;1(1):50-7. Semin Pediatr Neurol. 1994. PMID: 9422219 Review.
Infection with the human immunodeficiency virus type 1 (HIV-1) remains a major potential cause of neurological disorders in children and adults throughout the world. This article provides an overview regarding the epidemiology, clinical manifestations, and ne
Infection with the human immunodeficiency virus type 1 (HIV-1) remains a major potential cause of neurological disorder
Lipodystrophies.
Garg A. Garg A. Am J Med. 2000 Feb;108(2):143-52. doi: 10.1016/s0002-9343(99)00414-3. Am J Med. 2000. PMID: 11126308 Review.
Recently, a gene for congenital generalized lipodystrophy was localized to chromosome 9q34, and a gene for familial partial lipodystrophy, Dunnigan type, to chromosome 1q21-22; the genes, however, remain to be identified. ...Both varieties occur approximately three times m …
Recently, a gene for congenital generalized lipodystrophy was localized to chromosome 9q34, and a gene for familial partial lipodystr …
Decreased risk of congenital cytomegalovirus infection in children born to HIV-1-infected mothers in the era of highly active antiretroviral therapy.
Guibert G, Warszawski J, Le Chenadec J, Blanche S, Benmebarek Y, Mandelbrot L, Tubiana R, Rouzioux C, Leruez-Ville M; French Perinatal Cohort. Guibert G, et al. Clin Infect Dis. 2009 Jun 1;48(11):1516-25. doi: 10.1086/598934. Clin Infect Dis. 2009. PMID: 19388872
BACKGROUND: We evaluated the prevalence of congenital cytomegalovirus (CMV) infection before and after highly active antiretroviral therapy (HAART) availability among neonates born to human immunodeficiency virus type 1 (HIV-1)-infected mothers. …
BACKGROUND: We evaluated the prevalence of congenital cytomegalovirus (CMV) infection before and after highly active antiretro …
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein.
Hrecka K, Hao C, Gierszewska M, Swanson SK, Kesik-Brodacka M, Srivastava S, Florens L, Washburn MP, Skowronski J. Hrecka K, et al. Nature. 2011 Jun 29;474(7353):658-61. doi: 10.1038/nature10195. Nature. 2011. PMID: 21720370 Free PMC article.
Human immunodeficiency virus 1 (HIV-1) fails to transduce dendritic cells and has a reduced ability to transduce macrophages, due to an as yet uncharacterized mechanism that inhibits infection by interfering with efficient synthesis of viral complementary DNA …
Human immunodeficiency virus 1 (HIV-1) fails to transduce dendritic cells and has a reduced ability to transduce macrophages, …
370 results