[Component-based diagnostic approach. Detection of sensitization to lipid transfer proteins in food allergy]

Hautarzt. 2010 May;61(5):382-5. doi: 10.1007/s00105-010-1955-2.
[Article in German]

Abstract

Sensitization to lipid transfer proteins (LTPs), a pan-allergen in plants, causes severe anaphylactic reactions to foods, especially in the Mediterranean area. A component-based diagnostic approach identified the peach LTP Pru p 3 as a major allergen. We present the case of a 30-year-old LTP-sensitized Spanish woman with a history of severe anaphylactic reaction to grapes, apple and cauliflower in which the detection of specific IgE against the recombinant protein Pru p 3 led to the diagnosis.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Anaphylaxis / diagnosis*
  • Anaphylaxis / immunology*
  • Anaphylaxis / prevention & control
  • Antibody Specificity / immunology
  • Antigens, Plant / immunology*
  • Carrier Proteins / immunology*
  • Cross Reactions / immunology
  • Female
  • Food Hypersensitivity / diagnosis*
  • Food Hypersensitivity / diet therapy
  • Food Hypersensitivity / immunology
  • Humans
  • Hypersensitivity, Immediate / diagnosis*
  • Hypersensitivity, Immediate / diet therapy
  • Hypersensitivity, Immediate / immunology
  • Immunoglobulin E / blood*
  • Plant Proteins / immunology*

Substances

  • Antigens, Plant
  • Carrier Proteins
  • Plant Proteins
  • lipid transfer proteins, plant
  • Immunoglobulin E