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Clin Plast Surg. 2015 Oct;42(4):605-13. doi: 10.1016/j.cps.2015.06.006. Epub 2015 Aug 11.

Coming of Age: Breast Implant-Associated Anaplastic Large Cell Lymphoma After 18 Years of Investigation.

Author information

1
Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1488, Houston, TX 77030, USA. Electronic address: mwclemens@mdanderson.org.
2
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 0072, Houston, TX 77030, USA.

Abstract

Breast implant associated anaplastic large cell lymphoma (BIALCL) is a distinct clinical entity that can present in patients receiving either reconstructive or cosmetic breast implants. Presenting symptoms include onset of a delayed (>1 year after implantation) fluid collection, mass of the capsule, or lymphadenopathy. Treatment has progressed in recent years and most commonly includes implant removal and total resection of the tumor, including capsule, mass, and involved lymph nodes. Further research is warranted to determine potential malignant drivers, disease progression, and optimal treatment strategies in advanced disease.

KEYWORDS:

Anaplastic large cell lymphoma; Breast implant–associated ALCL; CD30; Non-Hodgkin lymphoma

PMID:
26408447
DOI:
10.1016/j.cps.2015.06.006
[Indexed for MEDLINE]

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