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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 2
1975 1
1977 1
1980 2
1982 1
1984 2
1985 3
1986 4
1987 6
1988 9
1989 9
1990 7
1991 8
1992 7
1993 7
1994 13
1995 18
1996 20
1997 12
1998 17
1999 20
2000 22
2001 19
2002 17
2003 20
2004 28
2005 18
2006 18
2007 17
2008 24
2009 24
2010 19
2011 24
2012 28
2013 35
2014 32
2015 33
2016 39
2017 47
2018 49
2019 50
2020 67
2021 63
2022 63
2023 68
2024 31

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930 results

Results by year

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Page 1
Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer.
Leidner R, Sanjuan Silva N, Huang H, Sprott D, Zheng C, Shih YP, Leung A, Payne R, Sutcliffe K, Cramer J, Rosenberg SA, Fox BA, Urba WJ, Tran E. Leidner R, et al. N Engl J Med. 2022 Jun 2;386(22):2112-2119. doi: 10.1056/NEJMoa2119662. N Engl J Med. 2022. PMID: 35648703 Free PMC article.
The patient had regression of visceral metastases (overall partial response of 72% according to the Response Evaluation Criteria in Solid Tumors, version 1.1); the response was ongoing at 6 months. ...In this patient, TCR gene therapy targeting the KRAS G12D driver mutatio …
The patient had regression of visceral metastases (overall partial response of 72% according to the Response Evaluation Criteria in S …
Mutational landscape of chronic myelomonocytic leukemia in Chinese patients.
Nie Y, Shao L, Zhang H, He CK, Li H, Zou J, Chen L, Ji H, Tan H, Lin Y, Ru K. Nie Y, et al. Exp Hematol Oncol. 2022 May 24;11(1):32. doi: 10.1186/s40164-022-00284-z. Exp Hematol Oncol. 2022. PMID: 35610628 Free PMC article.
The targeted next generation sequencing (NGS) was used to evaluate 114 gene variations, and the prognostic factors for OS were determined by COX regression analysis. RESULTS: The CMML patients showed a unique mutational spectrum, including TET2 (36.5%), NRAS (31.5%), ASXL1 …
The targeted next generation sequencing (NGS) was used to evaluate 114 gene variations, and the prognostic factors for OS were determined by …
Cutaneous mastocytosis: A dermatological perspective.
Di Raimondo C, Del Duca E, Silvaggio D, Di Prete M, Lombardo P, Mazzeo M, Spallone G, Campione E, Botti E, Bianchi L. Di Raimondo C, et al. Australas J Dermatol. 2021 Feb;62(1):e1-e7. doi: 10.1111/ajd.13443. Epub 2020 Oct 11. Australas J Dermatol. 2021. PMID: 33040350 Review.
Mastocytosis is a rare disease characterised by expansion and collection of clonal mast cells in various organs including the skin, bone marrow, spleen, lymph nodes and gastrointestinal tract. ...Paediatric patients, on the contrary, have often cutaneous manifestations wit …
Mastocytosis is a rare disease characterised by expansion and collection of clonal mast cells in various organs including the skin, b …
Prediction of risk for myeloid malignancy in clonal hematopoiesis.
Weeks LD, Niroula A, Neuberg D, Wong W, Lindsley RC, Luskin M, Berliner N, Stone RM, DeAngelo DJ, Soiffer R, Uddin MM, Griffin G, Vlasschaert C, Gibson CJ, Jaiswal S, Bick AG, Malcovati L, Natarajan P, Ebert BL. Weeks LD, et al. NEJM Evid. 2023 May;2(5):10.1056/evidoa2200310. doi: 10.1056/evidoa2200310. Epub 2023 Apr 25. NEJM Evid. 2023. PMID: 37483562 Free PMC article.
BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS) are defined by somatic mutations in genes associated with myeloid neoplasms (MN) at a variant allele fraction (VAF) 0.02, in the absence and p …
BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS) ar …
ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer.
Hsieh RC, Krishnan S, Wu RC, Boda AR, Liu A, Winkler M, Hsu WH, Lin SH, Hung MC, Chan LC, Bhanu KR, Srinivasamani A, De Azevedo RA, Chou YC, DePinho RA, Gubin M, Vilar E, Chen CH, Slay R, Jayaprakash P, Hegde SM, Hartley G, Lea ST, Prasad R, Morrow B, Couillault CA, Steiner M, Wang CC, Venkatesulu BP, Taniguchi C, Kim YSB, Chen J, Rudqvist NP, Curran MA. Hsieh RC, et al. Sci Immunol. 2022 Jun 10;7(72):eabl9330. doi: 10.1126/sciimmunol.abl9330. Epub 2022 Jun 10. Sci Immunol. 2022. PMID: 35687697 Free PMC article.
The combination of RT, anti-SIRPalpha, and anti-PD-1 reversed adaptive immune resistance and drove efficient TAA cross-presentation, resulting in robust TAA-specific CD8 T cell priming, functional activation of T effectors, and increased T cell clonality and clonal
The combination of RT, anti-SIRPalpha, and anti-PD-1 reversed adaptive immune resistance and drove efficient TAA cross-presentation, resulti …
Predictors of clonal evolution and myeloid neoplasia following immunosuppressive therapy in severe aplastic anemia.
Groarke EM, Patel BA, Shalhoub R, Gutierrez-Rodrigues F, Desai P, Leuva H, Zaimoku Y, Paton C, Spitofsky N, Lotter J, Rios O, Childs RW, Young DJ, Dulau-Florea A, Dunbar CE, Calvo KR, Wu CO, Young NS. Groarke EM, et al. Leukemia. 2022 Sep;36(9):2328-2337. doi: 10.1038/s41375-022-01636-8. Epub 2022 Jul 27. Leukemia. 2022. PMID: 35896822 Free PMC article.
Predictors, genetic characteristics, and long-term outcomes of patients with SAA who clonally evolved after immunosuppressive therapy (IST) were assessed. ...OS was 37% in high-risk clonal evolution by 5 years compared to 94% in low-risk. High-risk patients who unde …
Predictors, genetic characteristics, and long-term outcomes of patients with SAA who clonally evolved after immunosuppressive therapy …
Clonal Hematopoiesis and Acute Ischemic Stroke Outcomes.
Lee EJ, An HY, Lim J, Park KI, Choi SY, Jeong HY, Kang DW, Yang W, Kim JM, Ko SB, Lee SH, Yoon BW, Koh Y, Jung KH. Lee EJ, et al. Ann Neurol. 2023 Nov;94(5):836-847. doi: 10.1002/ana.26754. Epub 2023 Aug 12. Ann Neurol. 2023. PMID: 37532684
OBJECTIVE: The effect of clonal hematopoiesis of indeterminate potential (CHIP) on the manifestation and clinical outcomes of acute ischemic stroke (AIS) has not been fully elucidated. ...The prevalence of CHIP was compared between patients with AIS and age-matched healthy …
OBJECTIVE: The effect of clonal hematopoiesis of indeterminate potential (CHIP) on the manifestation and clinical outcomes of acute i …
Clonal origin and spread of metastatic prostate cancer.
Van Etten JL, Dehm SM. Van Etten JL, et al. Endocr Relat Cancer. 2016 Apr;23(4):R207-17. doi: 10.1530/ERC-16-0049. Epub 2016 Mar 21. Endocr Relat Cancer. 2016. PMID: 27000662 Free PMC article. Review.
The standard treatment for metastatic disease is surgical or chemical castration in the form of androgen deprivation therapy. Despite initial success and disease regression, resistance to therapy ultimately develops and the disease transitions to castration-resistant prost …
The standard treatment for metastatic disease is surgical or chemical castration in the form of androgen deprivation therapy. Despite initia …
Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood.
Schuermans A, Nakao T, Ruan Y, Koyama S, Yu Z, Uddin MM, Haidermota S, Hornsby W, Lewandowski AJ, Bick AG, Niroula A, Jaiswal S, Ebert BL, Natarajan P, Honigberg MC. Schuermans A, et al. J Am Heart Assoc. 2023 Jul 4;12(13):e030220. doi: 10.1161/JAHA.123.030220. Epub 2023 Jun 22. J Am Heart Assoc. 2023. PMID: 37345823 Free PMC article.
Background High and low birth weight are independently associated with increased cardiovascular disease risk in adulthood. Clonal hematopoiesis of indeterminate potential (CHIP), the age-related clonal expansion of hematopoietic cells with preleukemic somatic mutati …
Background High and low birth weight are independently associated with increased cardiovascular disease risk in adulthood. Clonal hem …
Multiparameter prediction of myeloid neoplasia risk.
Gu M, Kovilakam SC, Dunn WG, Marando L, Barcena C, Mohorianu I, Smith A, Kar SP, Fabre MA, Gerstung M, Cargo CA, Malcovati L, Quiros PM, Vassiliou GS. Gu M, et al. Nat Genet. 2023 Sep;55(9):1523-1530. doi: 10.1038/s41588-023-01472-1. Epub 2023 Aug 24. Nat Genet. 2023. PMID: 37620601 Free PMC article.
The myeloid neoplasms encompass acute myeloid leukemia, myelodysplastic syndromes and myeloproliferative neoplasms. Most cases arise from the shared ancestor of clonal hematopoiesis (CH). Here we analyze data from 454,340 UK Biobank participants, of whom 1,808 developed a …
The myeloid neoplasms encompass acute myeloid leukemia, myelodysplastic syndromes and myeloproliferative neoplasms. Most cases arise from th …
930 results