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Eur J Dermatol. 2013 Apr 1;23(2):218-23. doi: 10.1684/ejd.2013.1934.

Clinical complexity of Leishmania (Viannia) braziliensis infections amongst travelers.

Author information

1
Hautklinik Mikrobiologisches Institut-Universitätsklinikum Erlangen Wasserturmstraße 3/5, 91054 Erlangen Germany.

Abstract

The protozoan parasite Leishmania (Viannia) braziliensis is one of the main causes of cutaneous and mucocutaneous leishmaniasis in South America. Here, we describe three cases of L. (V.) braziliensis infection which were acquired during travelling in Bolivia, Peru or Paraguay and illustrate the phenotypic heterogeneity and therapeutic complexity of the disease. Two patients presented with unusual clinical manifestations, i.e. with prominent regional lymphadenopathy ("bubonic leishmaniasis") and with simultaneously emerged skin and mucosal lesions, respectively. Both patients insufficiently responded to oral treatment with miltefosine; resolution of the lesions was only achieved after a course of intravenous liposomal amphotericin B.

KEYWORDS:

Leishmania (V.) braziliensis; cutaneous leishmaniasis; mucosal leishmaniasis

PMID:
23557633
DOI:
10.1684/ejd.2013.1934
[Indexed for MEDLINE]

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