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Plast Reconstr Surg. 2018 Apr;141(4):586e-599e. doi: 10.1097/PRS.0000000000004262.

How to Diagnose and Treat Breast Implant-Associated Anaplastic Large Cell Lymphoma.

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Houston, Texas; Los Angeles, Calif.; and Scottsdale, Ariz. From the Departments of Plastic Surgery and Hematopathology, M. D. Anderson Cancer Center; the Department of Plastic Surgery, Keck School of Medicine, University of Southern California; and the Department of Plastic Surgery, Mayo Clinic.



After reading this article, the participant should be able to: 1. Describe the diagnostic criteria for breast implant-associated (BIA) anaplastic large cell lymphoma (ALCL). 2. Appropriately evaluate a patient with suspected BIA-ALCL, including appropriate imaging, laboratory tests, and pathologic evaluation. 3. Understand the operative treatment of BIA-ALCL, and indications for systemic chemotherapy and/or radiation therapy in advanced disease. 4. Understand treatment outcomes and prognosis based on stage of disease.


The goal of this continuing medical education module is to present the assessment of a patient with suspected breast implant-associated anaplastic large cell lymphoma, the evaluation and diagnosis, the preoperative oncologic workup, the formation and execution of a surgical treatment plan, and the inclusion of adjunct treatments when indicated. In addition, staging and disease progression for treatment of breast implant-associated anaplastic large cell lymphoma are discussed.

[Indexed for MEDLINE]

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