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Items: 1 to 20 of 89

1.

The epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism.

Feng Y, Wu M, Li S, He X, Tang J, Peng W, Zeng B, Deng C, Ren G, Xiang T.

J Exp Clin Cancer Res. 2018 Dec 13;37(1):313. doi: 10.1186/s13046-018-0979-9.

2.

Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model.

Luo F, Xie Y, Wang Z, Huang J, Tan Q, Sun X, Li F, Li C, Liu M, Zhang D, Xu M, Su N, Ni Z, Jiang W, Chang J, Chen H, Chen S, Xu X, Deng C, Wang Z, Du X, Chen L.

Mol Ther Nucleic Acids. 2018 Dec 7;13:291-302. doi: 10.1016/j.omtn.2018.09.012. Epub 2018 Sep 22.

3.

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.

Korkut A, Zaidi S, Kanchi RS, Rao S, Gough NR, Schultz A, Li X, Lorenzi PL, Berger AC, Robertson G, Kwong LN, Datto M, Roszik J, Ling S, Ravikumar V, Manyam G, Rao A, Shelley S, Liu Y, Ju Z, Hansel D, de Velasco G, Pennathur A, Andersen JB, O'Rourke CJ, Ohshiro K, Jogunoori W, Nguyen BN, Li S, Osmanbeyoglu HU, Ajani JA, Mani SA, Houseman A, Wiznerowicz M, Chen J, Gu S, Ma W, Zhang J, Tong P, Cherniack AD, Deng C, Resar L; Cancer Genome Atlas Research Network, Weinstein JN, Mishra L, Akbani R.

Cell Syst. 2018 Oct 24;7(4):422-437.e7. doi: 10.1016/j.cels.2018.08.010. Epub 2018 Sep 26.

4.

A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis.

Tan Q, Wang Z, Wang Q, Wang Y, Huang Z, Su N, Jin M, Kuang L, Qi H, Ni Z, Li C, Zhu Y, Jiang W, Chen H, Deng C, Du X, Xie Y, Chen L.

Int J Biol Sci. 2018 Jul 27;14(10):1389-1398. doi: 10.7150/ijbs.24739. eCollection 2018.

5.

Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice.

Wang Q, Tan Q, Xu W, Kuang L, Zhang B, Wang Z, Ni Z, Su N, Jin M, Li C, Jiang W, Huang J, Li F, Zhu Y, Chen H, Du X, Chen D, Deng C, Qi H, Xie Y, Chen L.

J Cell Physiol. 2018 Jan;234(1):595-605. doi: 10.1002/jcp.26802. Epub 2018 Aug 5.

PMID:
30078186
6.

A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells.

Chen Z, Liu J, Chu D, Shan Y, Ma G, Zhang H, Zhang XD, Wang P, Chen Q, Deng C, Chen W, Dimitrov DS, Zhao Q.

Int J Biol Sci. 2018 May 21;14(7):799-806. doi: 10.7150/ijbs.25928. eCollection 2018.

7.

Generation of Smurf2 Conditional Knockout Mice.

Tang Y, Tang LY, Xu X, Li C, Deng C, Zhang YE.

Int J Biol Sci. 2018 Apr 5;14(5):542-548. doi: 10.7150/ijbs.24303. eCollection 2018.

8.

Transforming growth factor-β in liver cancer stem cells and regeneration.

Rao S, Zaidi S, Banerjee J, Jogunoori W, Sebastian R, Mishra B, Nguyen BN, Wu RC, White J, Deng C, Amdur R, Li S, Mishra L.

Hepatol Commun. 2017 Jul 21;1(6):477-493. doi: 10.1002/hep4.1062. eCollection 2017 Aug. Review.

9.

Corrigendum to "Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism" [Mol Metabol 6 (2017) 1540-1550].

Xiao C, Piñol RA, Carlin JL, Li C, Deng C, Gavrilova O, Reitman ML.

Mol Metab. 2018 Mar;9:220. doi: 10.1016/j.molmet.2017.12.009. Epub 2017 Dec 27. No abstract available.

10.

Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism.

Xiao C, Piñol RA, Carlin JL, Li C, Deng C, Gavrilova O, Reitman ML.

Mol Metab. 2017 Nov;6(11):1540-1550. doi: 10.1016/j.molmet.2017.08.013. Epub 2017 Sep 15. Erratum in: Mol Metab. 2017 Dec 27;:.

11.

Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation.

Xu W, Luo F, Wang Q, Tan Q, Huang J, Zhou S, Wang Z, Sun X, Kuang L, Jin M, Su N, Jiang W, Chen L, Qi H, Zhu Y, Chen B, Chen H, Chen S, Gao Y, Xu X, Deng C, Chen L, Xie Y, Du X.

J Bone Miner Res. 2017 Nov;32(11):2194-2206. doi: 10.1002/jbmr.3204. Epub 2017 Sep 12.

12.

Epigenetic targeting drugs potentiate chemotherapeutic effects in solid tumor therapy.

Li J, Hao D, Wang L, Wang H, Wang Y, Zhao Z, Li P, Deng C, Di LJ.

Sci Rep. 2017 Jun 22;7(1):4035. doi: 10.1038/s41598-017-04406-0.

13.

Partial Müllerian Duct Retention in Smad4 Conditional Mutant Male Mice.

Petit FG, Deng C, Jamin SP.

Int J Biol Sci. 2016 Apr 21;12(6):667-76. doi: 10.7150/ijbs.12300. eCollection 2016.

14.

Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes.

Zhou ZQ, Ota S, Deng C, Akiyama H, Hurlin PJ.

Hum Mol Genet. 2015 Mar 15;24(6):1764-73. doi: 10.1093/hmg/ddu594. Epub 2014 Nov 28.

15.

Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism.

Masri S, Rigor P, Cervantes M, Ceglia N, Sebastian C, Xiao C, Roqueta-Rivera M, Deng C, Osborne TF, Mostoslavsky R, Baldi P, Sassone-Corsi P.

Cell. 2014 Jul 31;158(3):659-72. doi: 10.1016/j.cell.2014.06.050.

16.

Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells.

Vazquez-Ortiz G, Chisholm C, Xu X, Lahusen TJ, Li C, Sakamuru S, Huang R, Thomas CJ, Xia M, Deng C.

Breast Cancer Res. 2014 Jun 24;16(3):R67. doi: 10.1186/bcr3682.

17.

APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor.

Ryu J, Galan AK, Xin X, Dong F, Abdul-Ghani MA, Zhou L, Wang C, Li C, Holmes BM, Sloane LB, Austad SN, Guo S, Musi N, DeFronzo RA, Deng C, White MF, Liu F, Dong LQ.

Cell Rep. 2014 May 22;7(4):1227-38. doi: 10.1016/j.celrep.2014.04.006. Epub 2014 May 10.

18.

Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis.

Park JW, Jang SH, Park DM, Lim NJ, Deng C, Kim DY, Green JE, Kim HK.

Mol Cancer Res. 2014 Aug;12(8):1088-99. doi: 10.1158/1541-7786.MCR-14-0192-T. Epub 2014 Apr 30.

19.

BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks.

Willis NA, Chandramouly G, Huang B, Kwok A, Follonier C, Deng C, Scully R.

Nature. 2014 Jun 26;510(7506):556-9. doi: 10.1038/nature13295. Epub 2014 Apr 28.

20.

Diethylstilbestrol induces vaginal adenosis by disrupting SMAD/RUNX1-mediated cell fate decision in the Müllerian duct epithelium.

Laronda MM, Unno K, Ishi K, Serna VA, Butler LM, Mills AA, Orvis GD, Behringer RR, Deng C, Sinha S, Kurita T.

Dev Biol. 2013 Sep 1;381(1):5-16. doi: 10.1016/j.ydbio.2013.06.024. Epub 2013 Jul 4.

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