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Items: 1 to 20 of 177


SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions.

Kim TS, Jin YB, Kim YS, Kim S, Kim JK, Lee HM, Suh HW, Choe JH, Kim YJ, Koo BS, Kim HN, Jung M, Lee SH, Kim DK, Chung C, Son JW, Min JJ, Kim JM, Deng CX, Kim HS, Lee SR, Jo EK.

Autophagy. 2019 Feb 17:1-20. doi: 10.1080/15548627.2019.1582743. [Epub ahead of print]


PP2ACα deficiency impairs early cortical development through inducing DNA damage in neuroprojenitor cells.

Liu B, Lin L, Riazuddin S, Zubair A, Wang L, Di LJ, Li R, Dong TT, Deng CX, Tong WM.

Int J Biochem Cell Biol. 2019 Apr;109:40-58. doi: 10.1016/j.biocel.2019.01.021. Epub 2019 Jan 30.


Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers.

Huang T, Deng CX.

Int J Biol Sci. 2019 Jan 6;15(1):1-11. doi: 10.7150/ijbs.27796. eCollection 2019. Review.


Effect of Stromal Cells in Tumor Microenvironment on Metastasis Initiation.

Guo S, Deng CX.

Int J Biol Sci. 2018 Nov 13;14(14):2083-2093. doi: 10.7150/ijbs.25720. eCollection 2018. Review.


Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice.

Miao K, Zhang X, Su SM, Zeng J, Huang Z, Chan UI, Xu X, Deng CX.

J Biol Chem. 2019 Jan 25;294(4):1142-1151. doi: 10.1074/jbc.RA118.006496. Epub 2018 Nov 28.


BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy.

Xu X, Chen E, Mo L, Zhang L, Shao F, Miao K, Liu J, Su SM, Valecha M, In Chan U, Zheng H, Chen M, Chen W, Chen Q, Fu H, Aladjem MI, He Y, Deng CX.

Hum Mol Genet. 2018 Nov 15. doi: 10.1093/hmg/ddy398. [Epub ahead of print]


Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors.

Baek HJ, Kim SE, Kim JK, Shin DH, Kim TH, Kim KG, Deng CX, Kim SS.

Int J Biol Sci. 2018 Oct 3;14(13):1769-1781. doi: 10.7150/ijbs.29242. eCollection 2018.


Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation.

Baek HJ, Kim SE, Choi EK, Kim JK, Shin DH, Park EJ, Kim TH, Kim JY, Kim KG, Deng CX, Kim SS.

Int J Biol Sci. 2018 Oct 3;14(12):1755-1768. doi: 10.7150/ijbs.28142. eCollection 2018.


Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors.

Choi EK, Lim JA, Kim JK, Jang MS, Kim SE, Baek HJ, Park EJ, Kim TH, Deng CX, Wang RH, Kim SS.

Exp Mol Med. 2018 Oct 16;50(10):136. doi: 10.1038/s12276-018-0169-z.


BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition.

Zhang B, Lyu J, Liu Y, Wu C, Yang EJ, Pardeshi L, Tan K, Wong KH, Chen Q, Xu X, Deng CX, Shim JS.

Oncogene. 2018 Dec;37(49):6341-6356. doi: 10.1038/s41388-018-0408-8. Epub 2018 Jul 24.


Conditional Deletion of FOXL2 and SMAD4 in Gonadotropes of Adult Mice Causes Isolated FSH Deficiency.

Li Y, Schang G, Wang Y, Zhou X, Levasseur A, Boyer A, Deng CX, Treier M, Boehm U, Boerboom D, Bernard DJ.

Endocrinology. 2018 Jul 1;159(7):2641-2655. doi: 10.1210/en.2018-00100.


Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia.

Sun H, Miao Z, Zhang X, Chan UI, Su SM, Guo S, Wong CKH, Xu X, Deng CX.

J Biol Chem. 2018 Jun 1;293(22):8315-8329. doi: 10.1074/jbc.RA118.002297. Epub 2018 Apr 17.


The role of TGF-β/SMAD4 signaling in cancer.

Zhao M, Mishra L, Deng CX.

Int J Biol Sci. 2018 Jan 12;14(2):111-123. doi: 10.7150/ijbs.23230. eCollection 2018. Review.


BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis.

Lahusen TJ, Kim SJ, Miao K, Huang Z, Xu X, Deng CX.

Oncogene. 2018 Apr;37(17):2343-2350. doi: 10.1038/s41388-018-0127-1. Epub 2018 Feb 14.


A comprehensive genomic meta-analysis identifies confirmatory role of OBSCN gene in breast tumorigenesis.

Rajendran BK, Deng CX.

Oncotarget. 2017 Aug 23;8(60):102263-102276. doi: 10.18632/oncotarget.20404. eCollection 2017 Nov 24.


Erratum: PRAJA is overexpressed in glioblastoma and contributes to neural precursor development.

Shin J, Mishra V, Glasgow E, Zaidi S, Ohshiro K, Chitti B, Chen J, Kapadia AA, Rana N, Mishra L, Deng CX, Rao S, Mishra B.

Genes Cancer. 2017 Sep;8(9-10):745. doi: 10.18632/genesandcancer.158.


Alcohol, stem cells and cancer.

Gu S, Nguyen BN, Rao S, Li S, Shetty K, Rashid A, Shukla V, Deng CX, Mishra L, Mishra B.

Genes Cancer. 2017 Sep;8(9-10):695-700. doi: 10.18632/genesandcancer.156. Review.


Fibroblast Growth Factor Receptor 2 (FGFR2) Mutation Related Syndromic Craniosynostosis.

Azoury SC, Reddy S, Shukla V, Deng CX.

Int J Biol Sci. 2017 Nov 2;13(12):1479-1488. doi: 10.7150/ijbs.22373. eCollection 2017. Review.


A digital microfluidic system for loop-mediated isothermal amplification and sequence specific pathogen detection.

Wan L, Chen T, Gao J, Dong C, Wong AH, Jia Y, Mak PI, Deng CX, Martins RP.

Sci Rep. 2017 Nov 6;7(1):14586. doi: 10.1038/s41598-017-14698-x.


Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer.

Lei H, Deng CX.

Int J Biol Sci. 2017 Sep 5;13(9):1163-1171. doi: 10.7150/ijbs.20792. eCollection 2017. Review.

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