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Items: 1 to 20 of 42

1.

Prenatal diagnosis of pathogenic genomic imbalance in fetuses with increased nuchal translucency but normal karyotyping using chromosomal microarray.

Leung TY, Au Yeung KC, Leung WC, Leung KY, Lo TK, To WWK, Lau WL, Chan LW, Sahota DS, Choy RKW.

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):30-32. No abstract available.

2.

Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition.

Partridge JR, Choy RM, Silva-Garcia A, Yu C, Li Z, Sham H, Metcalf B.

J Struct Biol. 2019 May 1;206(2):170-182. doi: 10.1016/j.jsb.2019.03.001. Epub 2019 Mar 12.

3.

Optimization of Methionyl tRNA-Synthetase Inhibitors for Treatment of Cryptosporidium Infection.

Buckner FS, Ranade RM, Gillespie JR, Shibata S, Hulverson MA, Zhang Z, Huang W, Choi R, Verlinde CLMJ, Hol WGJ, Ochida A, Akao Y, Choy RKM, Van Voorhis WC, Arnold SLM, Jumani RS, Huston CD, Fan E.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02061-18. doi: 10.1128/AAC.02061-18. Print 2019 Apr.

4.

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.

Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]

5.

Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development.

Crawford JJ, Johnson AR, Misner DL, Belmont LD, Castanedo G, Choy R, Coraggio M, Dong L, Eigenbrot C, Erickson R, Ghilardi N, Hau J, Katewa A, Kohli PB, Lee W, Lubach JW, McKenzie BS, Ortwine DF, Schutt L, Tay S, Wei B, Reif K, Liu L, Wong H, Young WB.

J Med Chem. 2018 Mar 22;61(6):2227-2245. doi: 10.1021/acs.jmedchem.7b01712. Epub 2018 Feb 23.

PMID:
29457982
6.

Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya.

Rafferty ER, Schurer JM, Arndt MB, Choy RKM, de Hostos EL, Shoultz D, Farag M.

PLoS One. 2017 Aug 23;12(8):e0182820. doi: 10.1371/journal.pone.0182820. eCollection 2017.

7.

Interactome and reciprocal activation of pathways in topical mesenchymal stem cells and the recipient cerebral cortex following traumatic brain injury.

Lam PK, Wang KKW, Lo AWI, Tong CSW, Ching DWC, Wong K, Yang Z, Kong T, Lo KKY, Choy RKW, Lai PBS, Wong GKC, Poon WS.

Sci Rep. 2017 Jul 10;7(1):5017. doi: 10.1038/s41598-017-01772-7.

8.

Topical Application of Mesenchymal Stromal Cells Ameliorated Liver Parenchyma Damage After Ischemia-Reperfusion Injury in an Animal Model.

Lam PK, Chong CCN, Lo AWI, Chan AWH, Tong CSW, Chin DWC, Wong KHK, Choy RKW, Fung AK, Wang YX, To KF, Lai PBS.

Transplant Direct. 2017 May 11;3(6):e160. doi: 10.1097/TXD.0000000000000675. eCollection 2017 Jun.

9.

Effects of Racecadotril on Weight Loss and Diarrhea Due to Human Rotavirus in Neonatal Gnotobiotic Pigs (Sus scrofa domesticus).

Bui T, Li G, Kim I, Wen K, Twitchell EL, Hualei S, Ramesh AK, Weiss MD, Yang X, Glark-Deener SG, Choy RK, Yuan L.

Comp Med. 2017 Mar 1;67(2):157-164.

10.

Concurrent Imaging of Receptor Trafficking and Calcium Dynamics by Spinning Disk Confocal Microscopy.

Larsen DD, Choy RW, Park M.

Methods Mol Biol. 2017;1538:249-259.

PMID:
27943195
11.

Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations.

Johnson AR, Kohli PB, Katewa A, Gogol E, Belmont LD, Choy R, Penuel E, Burton L, Eigenbrot C, Yu C, Ortwine DF, Bowman K, Franke Y, Tam C, Estevez A, Mortara K, Wu J, Li H, Lin M, Bergeron P, Crawford JJ, Young WB.

ACS Chem Biol. 2016 Oct 21;11(10):2897-2907. Epub 2016 Sep 7.

PMID:
27571029
12.

Longitudinal follow-up of levator ani muscle avulsion: does a second delivery affect it?

Chan SSC, Cheung RYK, Lee LL, Choy RKW, Chung TKH.

Ultrasound Obstet Gynecol. 2017 Jul;50(1):110-115. doi: 10.1002/uog.16009. Epub 2017 Jun 5.

13.

Human epigenetic alterations in Mycobacterium tuberculosis infection: a novel platform to eavesdrop interactions between M tuberculosis and host immunity.

Ip M, Zheng L, Leung ET, Lee N, Lui G, To KF, Choy R, Wong K, Chan EW, Chan RC.

Hong Kong Med J. 2015 Dec;21 Suppl 7:S31-5. No abstract available.

14.

Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea.

Griggs DW, Prinsen MJ, Oliva J, Campbell MA, Arnett SD, Tajfirouz D, Ruminski PG, Yu Y, Bond BR, Ji Y, Neckermann G, Choy RK, de Hostos E, Meyers MJ.

J Pharmacol Exp Ther. 2016 May;357(2):423-31. doi: 10.1124/jpet.115.231167. Epub 2016 Feb 23.

15.

Addressing Cryptosporidium Infection among Young Children in Low-Income Settings: The Crucial Role of New and Existing Drugs for Reducing Morbidity and Mortality.

Shoultz DA, de Hostos EL, Choy RK.

PLoS Negl Trop Dis. 2016 Jan 28;10(1):e0004242. doi: 10.1371/journal.pntd.0004242. eCollection 2016 Jan. No abstract available.

16.

Near-fatal neonatal coronary ischaemia associated with intermittent aortic regurgitation: successful surgical treatment.

Likes ML, Silverman NH, Albers EL, Choy R, Bhat A, McMullan DM.

Cardiol Young. 2015 Dec;25(8):1531-5. doi: 10.1017/S1047951115002024.

PMID:
26675600
17.

[The value of blastocyst culture on preimplantation genetic diagnosis].

Ou J, Wang W, Ma Y, Zhou Z, Ding J, Wang F, Duan C, Li L, Zheng A, Chong W, Choy R, Li H.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015 Jun;32(3):312-7. doi: 10.3760/cma.j.issn.1003-9406.2015.03.002. Chinese.

PMID:
26037339
18.

Anomalous aortic origin of the right coronary artery: Embryology over genetics.

Patel AM, Sunkara NT, Choy RM, Setty SP.

J Thorac Cardiovasc Surg. 2015 Apr;149(4):e65-6. doi: 10.1016/j.jtcvs.2014.12.055. Epub 2014 Dec 29. No abstract available.

19.

Cell-free urinary microRNA-99a and microRNA-125b are diagnostic markers for the non-invasive screening of bladder cancer.

Zhang DZ, Lau KM, Chan ES, Wang G, Szeto CC, Wong K, Choy RK, Ng CF.

PLoS One. 2014 Jul 11;9(7):e100793. doi: 10.1371/journal.pone.0100793. eCollection 2014.

20.

Retromer mediates a discrete route of local membrane delivery to dendrites.

Choy RW, Park M, Temkin P, Herring BE, Marley A, Nicoll RA, von Zastrow M.

Neuron. 2014 Apr 2;82(1):55-62. doi: 10.1016/j.neuron.2014.02.018.

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