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FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination.
Fernandes JB, Duhamel M, Seguéla-Arnaud M, Froger N, Girard C, Choinard S, Solier V, De Winne N, De Jaeger G, Gevaert K, Andrey P, Grelon M, Guerois R, Kumar R, Mercier R. Fernandes JB, et al. Among authors: choinard s. PLoS Genet. 2018 Apr 2;14(4):e1007317. doi: 10.1371/journal.pgen.1007317. eCollection 2018 Apr. PLoS Genet. 2018. PMID: 29608566 Free PMC article.
RMI1 and TOP3α limit meiotic CO formation through their C-terminal domains.
Séguéla-Arnaud M, Choinard S, Larchevêque C, Girard C, Froger N, Crismani W, Mercier R. Séguéla-Arnaud M, et al. Among authors: choinard s. Nucleic Acids Res. 2017 Feb 28;45(4):1860-1871. doi: 10.1093/nar/gkw1210. Nucleic Acids Res. 2017. PMID: 27965412 Free PMC article.
Multiple mechanisms limit meiotic crossovers: TOP3α and two BLM homologs antagonize crossovers in parallel to FANCM.
Séguéla-Arnaud M, Crismani W, Larchevêque C, Mazel J, Froger N, Choinard S, Lemhemdi A, Macaisne N, Van Leene J, Gevaert K, De Jaeger G, Chelysheva L, Mercier R. Séguéla-Arnaud M, et al. Among authors: choinard s. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4713-8. doi: 10.1073/pnas.1423107112. Epub 2015 Mar 30. Proc Natl Acad Sci U S A. 2015. PMID: 25825745 Free PMC article.