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Items: 1 to 20 of 154

1.

Early decreases in blood eosinophil levels with reslizumab.

Chanez P, McDonald M, Garin M, Murphy K.

J Allergy Clin Immunol. 2019 Jan 14. pii: S0091-6749(19)30010-7. doi: 10.1016/j.jaci.2018.12.997. [Epub ahead of print]

PMID:
30654046
2.

"T2-high" in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin.

Pavlidis S, Takahashi K, Ng Kee Kwong F, Xie J, Hoda U, Sun K, Elyasigomari V, Agapow P, Loza M, Baribaud F, Chanez P, Fowler SJ, Shaw DE, Fleming LJ, Howarth PH, Sousa AR, Corfield J, Auffray C, De Meulder B, Knowles R, Sterk PJ, Guo Y, Adcock IM, Djukanovic R, Fan Chung K; on behalf of the U-BIOPRED Study Group.

Eur Respir J. 2019 Jan 3;53(1). pii: 1800938. doi: 10.1183/13993003.00938-2018. Print 2019 Jan.

PMID:
30578390
3.

KIT as a therapeutic target for non-oncological diseases.

Martinez-Anton A, Gras D, Bourdin A, Dubreuil P, Chanez P.

Pharmacol Ther. 2018 Dec 14. pii: S0163-7258(18)30230-4. doi: 10.1016/j.pharmthera.2018.12.008. [Epub ahead of print] Review.

PMID:
30557630
4.

Persistent Reduction of Mucin Production Following Bronchial Thermoplasty in Severe Asthma.

Haj Salem I, Gras D, Joubert P, Boulet LP, Lampron N, Martel S, Godbout K, Chanez P, Laviolette M, Chakir J.

Am J Respir Crit Care Med. 2018 Dec 12. doi: 10.1164/rccm.201811-2064LE. [Epub ahead of print] No abstract available.

PMID:
30540915
5.

Identification and prospective stability of electronic nose (eNose)-derived inflammatory phenotypes in patients with severe asthma.

Brinkman P, Wagener AH, Hekking PP, Bansal AT, Maitland-van der Zee AH, Wang Y, Weda H, Knobel HH, Vink TJ, Rattray NJ, D'Amico A, Pennazza G, Santonico M, Lefaudeux D, De Meulder B, Auffray C, Bakke PS, Caruso M, Chanez P, Chung KF, Corfield J, Dahlén SE, Djukanovic R, Geiser T, Horvath I, Krug N, Musial J, Sun K, Riley JH, Shaw DE, Sandström T, Sousa AR, Montuschi P, Fowler SJ, Sterk PJ; U-BIOPRED Study Group.

J Allergy Clin Immunol. 2018 Dec 6. pii: S0091-6749(18)31722-6. doi: 10.1016/j.jaci.2018.10.058. [Epub ahead of print]

PMID:
30529449
6.

Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort.

Emma R, Bansal AT, Kolmert J, Wheelock CE, Dahlen SE, Loza MJ, De Meulder B, Lefaudeux D, Auffray C, Dahlen B, Bakke PS, Chanez P, Fowler SJ, Horvath I, Montuschi P, Krug N, Sanak M, Sandstrom T, Shaw DE, Fleming LJ, Djukanovic R, Howarth PH, Singer F, Sousa AR, Sterk PJ, Corfield J, Pandis I, Chung KF, Adcock IM, Lutter R, Fabbella L, Caruso M; U-BIOPRED Study Group.

PLoS One. 2018 Sep 21;13(9):e0203874. doi: 10.1371/journal.pone.0203874. eCollection 2018.

7.

Dupilumab improves symptoms, quality of life, and productivity in uncontrolled persistent asthma.

Corren J, Castro M, Chanez P, Fabbri L, Joish VN, Amin N, Graham NMH, Mastey V, Abbé A, Taniou C, Mahajan P, Teper A, Pirozzi G, Eckert L.

Ann Allergy Asthma Immunol. 2019 Jan;122(1):41-49.e2. doi: 10.1016/j.anai.2018.08.005. Epub 2018 Aug 21.

8.

Reply to Upham: The Bronchial Epithelial Secretory IgA System in Asthma.

Ladjemi MZ, Gras D, Gohy S, Chanez P, Pilette C.

Am J Respir Crit Care Med. 2018 Nov 1;198(9):1236-1238. doi: 10.1164/rccm.201806-1128LE. No abstract available.

PMID:
30059234
9.

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.

Jevnikar Z, Östling J, Ax E, Calvén J, Thörn K, Israelsson E, Öberg L, Singhania A, Lau LCK, Wilson SJ, Ward JA, Chauhan A, Sousa AR, De Meulder B, Loza MJ, Baribaud F, Sterk PJ, Chung KF, Sun K, Guo Y, Adcock IM, Payne D, Dahlen B, Chanez P, Shaw DE, Krug N, Hohlfeld JM, Sandström T, Djukanovic R, James A, Hinks TSC, Howarth PH, Vaarala O, van Geest M, Olsson H; Unbiased Biomarkers in Prediction of Respiratory Disease Outcomes study group.

J Allergy Clin Immunol. 2018 Jun 11. pii: S0091-6749(18)30847-9. doi: 10.1016/j.jaci.2018.05.026. [Epub ahead of print]

10.

Bronchial Thermoplasty in Severe Asthma: Best Practice Recommendations from an Expert Panel.

Bonta PI, Chanez P, Annema JT, Shah PL, Niven R.

Respiration. 2018;95(5):289-300. doi: 10.1159/000488291. Epub 2018 Apr 17. Review.

PMID:
29669351
11.

Bronchial Epithelial IgA Secretion Is Impaired in Asthma. Role of IL-4/IL-13.

Ladjemi MZ, Gras D, Dupasquier S, Detry B, Lecocq M, Garulli C, Fregimilicka C, Bouzin C, Gohy S, Chanez P, Pilette C.

Am J Respir Crit Care Med. 2018 Jun 1;197(11):1396-1409. doi: 10.1164/rccm.201703-0561OC.

PMID:
29652177
12.

Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.

Takahashi K, Pavlidis S, Ng Kee Kwong F, Hoda U, Rossios C, Sun K, Loza M, Baribaud F, Chanez P, Fowler SJ, Horvath I, Montuschi P, Singer F, Musial J, Dahlen B, Dahlen SE, Krug N, Sandstrom T, Shaw DE, Lutter R, Bakke P, Fleming LJ, Howarth PH, Caruso M, Sousa AR, Corfield J, Auffray C, De Meulder B, Lefaudeux D, Djukanovic R, Sterk PJ, Guo Y, Adcock IM, Chung KF; , on behalf of the U-BIOPRED study group.

Eur Respir J. 2018 May 3;51(5). pii: 1702173. doi: 10.1183/13993003.02173-2017. Print 2018 May.

PMID:
29650557
13.

HLA-G Haplotypes Are Differentially Associated with Asthmatic Features.

Ribeyre C, Carlini F, René C, Jordier F, Picard C, Chiaroni J, Abi-Rached L, Gouret P, Marin G, Molinari N, Chanez P, Paganini J, Gras D, Di Cristofaro J.

Front Immunol. 2018 Feb 23;9:278. doi: 10.3389/fimmu.2018.00278. eCollection 2018.

14.

Spatiotemporal organization of cilia drives multiscale mucus swirls in model human bronchial epithelium.

Khelloufi MK, Loiseau E, Jaeger M, Molinari N, Chanez P, Gras D, Viallat A.

Sci Rep. 2018 Feb 5;8(1):2447. doi: 10.1038/s41598-018-20882-4.

15.

Asthma, COPD, and overlap in a national cohort: ACO on a gradient.

Bourdin A, Suehs CM, Marin G, Vachier I, Matzner-Lober E, Chanez P, Molinari N; COBRA Consortium.

J Allergy Clin Immunol. 2018 Apr;141(4):1516-1518. doi: 10.1016/j.jaci.2017.11.049. Epub 2018 Jan 31. No abstract available.

PMID:
29355677
16.

Circulating tumour cells as a potential screening tool for lung cancer (the AIR study): protocol of a prospective multicentre cohort study in France.

Leroy S, Benzaquen J, Mazzetta A, Marchand-Adam S, Padovani B, Israel-Biet D, Pison C, Chanez P, Cadranel J, Mazières J, Jounieaux V, Cohen C, Hofman V, Ilie M, Hofman P, Marquette CH; AIR Project Study Group.

BMJ Open. 2017 Dec 26;7(12):e018884. doi: 10.1136/bmjopen-2017-018884.

17.

Radiological abnormalities following bronchial thermoplasty: is the pathophysiology understood?

Debray MP, Dombret MC, Pretolani M, Thabut G, Alavoine L, Brillet PY, Taillé C, Khalil A, Chanez P, Aubier M.

Eur Respir J. 2017 Dec 7;50(6). pii: 1702067. doi: 10.1183/13993003.02067-2017. Print 2017 Dec. No abstract available.

PMID:
29217610
18.

Mortality: a neglected outcome in OCS-treated severe asthma.

Bourdin A, Molinari N, Vachier I, Pahus L, Suehs C, Chanez P.

Eur Respir J. 2017 Nov 30;50(5). pii: 1701486. doi: 10.1183/13993003.01486-2017. Print 2017 Nov. No abstract available.

PMID:
29191955
19.

Lung development, regeneration and plasticity: From disease physiopathology to drug design using induced pluripotent stem cells.

Ahmed E, Sansac C, Assou S, Gras D, Petit A, Vachier I, Chanez P, De Vos J, Bourdin A.

Pharmacol Ther. 2018 Mar;183:58-77. doi: 10.1016/j.pharmthera.2017.10.002. Epub 2017 Oct 4. Review.

PMID:
28987320
20.

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease.

Pavord ID, Chanez P, Criner GJ, Kerstjens HAM, Korn S, Lugogo N, Martinot JB, Sagara H, Albers FC, Bradford ES, Harris SS, Mayer B, Rubin DB, Yancey SW, Sciurba FC.

N Engl J Med. 2017 Oct 26;377(17):1613-1629. doi: 10.1056/NEJMoa1708208. Epub 2017 Sep 11.

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