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Items: 1 to 20 of 31


Engineering genetically-encoded tools for optogenetic control of protein activity.

Liu Q, Tucker CL.

Curr Opin Chem Biol. 2017 Oct;40:17-23. doi: 10.1016/j.cbpa.2017.05.001. Epub 2017 May 17. Review.


Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2.

Pathak GP, Spiltoir JI, Höglund C, Polstein LR, Heine-Koskinen S, Gersbach CA, Rossi J, Tucker CL.

Nucleic Acids Res. 2017 Nov 16;45(20):e167. doi: 10.1093/nar/gkx260.


Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase.

Taslimi A, Zoltowski B, Miranda JG, Pathak GP, Hughes RM, Tucker CL.

Nat Chem Biol. 2016 Jun;12(6):425-30. doi: 10.1038/nchembio.2063. Epub 2016 Apr 11.


Optical Control of Peroxisomal Trafficking.

Spiltoir JI, Strickland D, Glotzer M, Tucker CL.

ACS Synth Biol. 2016 Jul 15;5(7):554-60. doi: 10.1021/acssynbio.5b00144. Epub 2015 Nov 2.


Photo-activatable Cre recombinase regulates gene expression in vivo.

Schindler SE, McCall JG, Yan P, Hyrc KL, Li M, Tucker CL, Lee JM, Bruchas MR, Diamond MI.

Sci Rep. 2015 Sep 9;5:13627. doi: 10.1038/srep13627.


Benchmarking of optical dimerizer systems.

Pathak GP, Strickland D, Vrana JD, Tucker CL.

ACS Synth Biol. 2014 Nov 21;3(11):832-8. doi: 10.1021/sb500291r. Epub 2014 Nov 5.


An optimized optogenetic clustering tool for probing protein interaction and function.

Taslimi A, Vrana JD, Chen D, Borinskaya S, Mayer BJ, Kennedy MJ, Tucker CL.

Nat Commun. 2014 Sep 18;5:4925. doi: 10.1038/ncomms5925.


Tools for controlling protein interactions using light.

Tucker CL, Vrana JD, Kennedy MJ.

Curr Protoc Cell Biol. 2014 Sep 2;64:17.16.1-20. doi: 10.1002/0471143030.cb1716s64. Review.


Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders.

Hanson MG, Fregoso VL, Vrana JD, Tucker CL, Niswander LA.

Dev Biol. 2014 Nov 1;395(1):84-95. doi: 10.1016/j.ydbio.2014.08.026. Epub 2014 Aug 28.


Allele-specific characterization of alanine: glyoxylate aminotransferase variants associated with primary hyperoxaluria.

Lage MD, Pittman AM, Roncador A, Cellini B, Tucker CL.

PLoS One. 2014 Apr 9;9(4):e94338. doi: 10.1371/journal.pone.0094338. eCollection 2014.


Optogenetic control of cell function using engineered photoreceptors.

Pathak GP, Vrana JD, Tucker CL.

Biol Cell. 2013 Feb;105(2):59-72. doi: 10.1111/boc.201200056. Epub 2012 Dec 21. Review.


Rapid profiling of disease alleles using a tunable reporter of protein misfolding.

Pittman AM, Lage MD, Poltoratsky V, Vrana JD, Paiardini A, Roncador A, Cellini B, Hughes RM, Tucker CL.

Genetics. 2012 Nov;192(3):831-42. doi: 10.1534/genetics.112.143750. Epub 2012 Aug 24.


Light-mediated control of DNA transcription in yeast.

Hughes RM, Bolger S, Tapadia H, Tucker CL.

Methods. 2012 Dec;58(4):385-91. doi: 10.1016/j.ymeth.2012.08.004. Epub 2012 Aug 15.


Light-dependent, dark-promoted interaction between Arabidopsis cryptochrome 1 and phytochrome B proteins.

Hughes RM, Vrana JD, Song J, Tucker CL.

J Biol Chem. 2012 Jun 22;287(26):22165-72. doi: 10.1074/jbc.M112.360545. Epub 2012 May 10.


Manipulating cellular processes using optical control of protein-protein interactions.

Tucker CL.

Prog Brain Res. 2012;196:95-117. doi: 10.1016/B978-0-444-59426-6.00006-9. Review.


The HSF-like transcription factor TBF1 is a major molecular switch for plant growth-to-defense transition.

Pajerowska-Mukhtar KM, Wang W, Tada Y, Oka N, Tucker CL, Fonseca JP, Dong X.

Curr Biol. 2012 Jan 24;22(2):103-12. doi: 10.1016/j.cub.2011.12.015. Epub 2012 Jan 12.


Rapid blue-light-mediated induction of protein interactions in living cells.

Kennedy MJ, Hughes RM, Peteya LA, Schwartz JW, Ehlers MD, Tucker CL.

Nat Methods. 2010 Dec;7(12):973-5. doi: 10.1038/nmeth.1524. Epub 2010 Oct 31.


Evaluation of cytarabine against Ewing sarcoma xenografts by the pediatric preclinical testing program.

Houghton PJ, Morton CL, Kang M, Reynolds CP, Billups CA, Favours E, Payne-Turner D, Tucker C, Smith MA.

Pediatr Blood Cancer. 2010 Dec 1;55(6):1224-6. doi: 10.1002/pbc.22355.


Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements.

West GM, Tucker CL, Xu T, Park SK, Han X, Yates JR 3rd, Fitzgerald MC.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9078-82. doi: 10.1073/pnas.1000148107. Epub 2010 May 3.


Hydrogen/deuterium exchange- and protease digestion-based screening assay for protein-ligand binding detection.

Hopper ED, Pittman AM, Tucker CL, Campa MJ, Patz EF Jr, Fitzgerald MC.

Anal Chem. 2009 Aug 15;81(16):6860-7. doi: 10.1021/ac900854t.

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