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Items: 1 to 20 of 54


Application of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma.

Xie J, Xu X, Yin P, Li Y, Guo H, Kujawa S, Chakravarti D, Bulun S, Kim JJ, Wei JJ.

Lab Invest. 2018 Sep 11. doi: 10.1038/s41374-018-0117-5. [Epub ahead of print]


Comparative analysis of AKT and the related biomarkers in uterine leiomyomas with MED12, HMGA2, and FH mutations.

Xie J, Ubango J, Ban Y, Chakravarti D, Kim JJ, Wei JJ.

Genes Chromosomes Cancer. 2018 Oct;57(10):485-494. doi: 10.1002/gcc.22643. Epub 2018 Aug 20.


The AKT/BCL-2 axis mediates survival of uterine leiomyoma in a novel 3D spheroid model.

Vidimar V, Chakravarti D, Bulun SE, Yin P, Nowak R, Wei JJ, Kim JJ.

Endocrinology. 2018 Jan 26. doi: 10.1210/en.2017-03191. [Epub ahead of print]


Feeling Stressed under the Sun? RPA1 Acetylation to the Rescue.

Chakravarti D, Hazra TK.

Cell Rep. 2017 Aug 29;20(9):1995-1996. doi: 10.1016/j.celrep.2017.08.045.


Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas.

Vidimar V, Gius D, Chakravarti D, Bulun SE, Wei JJ, Kim JJ.

Sci Adv. 2016 Nov 4;2(11):e1601132. eCollection 2016 Nov.


KAT8 Regulates Androgen Signaling in Prostate Cancer Cells.

Kim JY, Yu J, Abdulkadir SA, Chakravarti D.

Mol Endocrinol. 2016 Aug;30(8):925-36. doi: 10.1210/me.2016-1024. Epub 2016 Jun 7.


Decreased expression of microRNA-29 family in leiomyoma contributes to increased major fibrillar collagen production.

Marsh EE, Steinberg ML, Parker JB, Wu J, Chakravarti D, Bulun SE.

Fertil Steril. 2016 Sep 1;106(3):766-72. doi: 10.1016/j.fertnstert.2016.05.001. Epub 2016 May 24.


Genomic Determinants of THAP11/ZNF143/HCFC1 Complex Recruitment to Chromatin.

Vinckevicius A, Parker JB, Chakravarti D.

Mol Cell Biol. 2015 Dec;35(24):4135-46. doi: 10.1128/MCB.00477-15. Epub 2015 Sep 28.


LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer.

Zhang A, Zhao JC, Kim J, Fong KW, Yang YA, Chakravarti D, Mo YY, Yu J.

Cell Rep. 2015 Oct 6;13(1):209-221. doi: 10.1016/j.celrep.2015.08.069. Epub 2015 Sep 24.


Uterine Leiomyoma Stem Cells: Linking Progesterone to Growth.

Bulun SE, Moravek MB, Yin P, Ono M, Coon JS 5th, Dyson MT, Navarro A, Marsh EE, Zhao H, Maruyama T, Chakravarti D, Kim JJ, Wei JJ.

Semin Reprod Med. 2015 Sep;33(5):357-65. doi: 10.1055/s-0035-1558451. Epub 2015 Aug 6. Review.


Human uterine leiomyoma stem/progenitor cells expressing CD34 and CD49b initiate tumors in vivo.

Yin P, Ono M, Moravek MB, Coon JS 5th, Navarro A, Monsivais D, Dyson MT, Druschitz SA, Malpani SS, Serna VA, Qiang W, Chakravarti D, Kim JJ, Bulun SE.

J Clin Endocrinol Metab. 2015 Apr;100(4):E601-6. doi: 10.1210/jc.2014-2134. Epub 2015 Feb 6.


Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143.

Parker JB, Yin H, Vinckevicius A, Chakravarti D.

Cell Rep. 2014 Nov 6;9(3):967-82. doi: 10.1016/j.celrep.2014.09.051. Epub 2014 Oct 30.


Ovarian steroids, stem cells and uterine leiomyoma: therapeutic implications.

Moravek MB, Yin P, Ono M, Coon JS 5th, Dyson MT, Navarro A, Marsh EE, Chakravarti D, Kim JJ, Wei JJ, Bulun SE.

Hum Reprod Update. 2015 Jan-Feb;21(1):1-12. doi: 10.1093/humupd/dmu048. Epub 2014 Sep 8. Review.


A role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone H3 during androgen signaling and in prostate cancer.

Kim JY, Banerjee T, Vinckevicius A, Luo Q, Parker JB, Baker MR, Radhakrishnan I, Wei JJ, Barish GD, Chakravarti D.

Mol Cell. 2014 May 22;54(4):613-25. doi: 10.1016/j.molcel.2014.03.043. Epub 2014 May 1. Erratum in: Mol Cell. 2015 May 7;58(3):557.


Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth.

Ono M, Yin P, Navarro A, Moravek MB, Coon JS 5th, Druschitz SA, Serna VA, Qiang W, Brooks DC, Malpani SS, Ma J, Ercan CM, Mittal N, Monsivais D, Dyson MT, Yemelyanov A, Maruyama T, Chakravarti D, Kim JJ, Kurita T, Gottardi CJ, Bulun SE.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17053-8. doi: 10.1073/pnas.1313650110. Epub 2013 Sep 30.


MK-2206, an AKT inhibitor, promotes caspase-independent cell death and inhibits leiomyoma growth.

Sefton EC, Qiang W, Serna V, Kurita T, Wei JJ, Chakravarti D, Kim JJ.

Endocrinology. 2013 Nov;154(11):4046-57. doi: 10.1210/en.2013-1389. Epub 2013 Sep 3.


Ligand-activated peroxisome proliferator-activated receptor β/δ modulates human endometrial cancer cell survival.

Ma JJ, Monsivais D, Dyson MT, Coon JS, Malpani S, Ono M, Zhao H, Xin H, Pavone ME, Kim JJ, Chakravarti D, Bulun SE.

Horm Cancer. 2013 Dec;4(6):358-70. doi: 10.1007/s12672-013-0157-7. Epub 2013 Aug 14.


Expression profiling of nuclear receptors identifies key roles of NR4A subfamily in uterine fibroids.

Yin H, Lo JH, Kim JY, Marsh EE, Kim JJ, Ghosh AK, Bulun S, Chakravarti D.

Mol Endocrinol. 2013 May;27(5):726-40. doi: 10.1210/me.2012-1305. Epub 2013 Apr 2.


Chromatin immunoprecipitation: advancing analysis of nuclear hormone signaling.

Vinckevicius A, Chakravarti D.

J Mol Endocrinol. 2012 Sep 5;49(2):R113-23. doi: 10.1530/JME-12-0016. Print 2012 Oct. Review.


KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia.

Kim JY, Kim KB, Eom GH, Choe N, Kee HJ, Son HJ, Oh ST, Kim DW, Pak JH, Baek HJ, Kook H, Hahn Y, Kook H, Chakravarti D, Seo SB.

Mol Cell Biol. 2012 Jul;32(14):2917-33. doi: 10.1128/MCB.00133-12. Epub 2012 May 21.

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