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Xenobiotic-metabolizing enzymes in Bacillus anthracis: molecular and functional analysis of a truncated arylamine N-acetyltransferase isozyme.

Kubiak X, Duval R, Pluvinage B, Chaffotte AF, Dupret JM, Rodrigues-Lima F.

Br J Pharmacol. 2017 Jul;174(14):2174-2182. doi: 10.1111/bph.13647. Epub 2016 Nov 12.


Deciphering the unconventional peptide binding to the PDZ domain of MAST2.

Delhommel F, Chaffotte A, Terrien E, Raynal B, Buc H, Delepierre M, Cordier F, Wolff N.

Biochem J. 2015 Jul 1;469(1):159-68. doi: 10.1042/BJ20141198. Epub 2015 May 5.


Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A.

Xu X, Li de la Sierra-Gallay I, Kubiak X, Duval R, Chaffotte AF, Dupret JM, Haouz A, Rodrigues-Lima F.

Acta Crystallogr D Biol Crystallogr. 2015 Feb;71(Pt 2):266-73. doi: 10.1107/S139900471402522X. Epub 2015 Jan 23.


Quantitative and dynamic analysis of PTEN phosphorylation by NMR.

Cordier F, Chaffotte A, Wolff N.

Methods. 2015 May;77-78:82-91. doi: 10.1016/j.ymeth.2014.10.007. Epub 2014 Oct 18. Review.


Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain.

Maisonneuve P, Caillet-Saguy C, Raynal B, Gilquin B, Chaffotte A, Pérez J, Zinn-Justin S, Delepierre M, Buc H, Cordier F, Wolff N.

FEBS J. 2014 Nov;281(21):4852-65. doi: 10.1111/febs.13024. Epub 2014 Sep 30.


Interaction of a partially disordered antisigma factor with its partner, the signaling domain of the TonB-dependent transporter HasR.

Malki I, Simenel C, Wojtowicz H, de Amorim GC, Prochnicka-Chalufour A, Hoos S, Raynal B, England P, Chaffotte A, Delepierre M, Delepelaire P, Izadi-Pruneyre N.

PLoS One. 2014 Apr 11;9(4):e89502. doi: 10.1371/journal.pone.0089502. eCollection 2014.


Structural and biochemical characterization of an active arylamine N-acetyltransferase possessing a non-canonical Cys-His-Glu catalytic triad.

Kubiak X, Li de la Sierra-Gallay I, Chaffotte AF, Pluvinage B, Weber P, Haouz A, Dupret JM, Rodrigues-Lima F.

J Biol Chem. 2013 Aug 2;288(31):22493-505. doi: 10.1074/jbc.M113.468595. Epub 2013 Jun 16.


New insights for native production of MSP1(19), the disulfide-rich C-terminal fragment from Plasmodium falciparum merozoite surface protein 1.

Planson AG, Guijarro JI, Chaffotte AF.

PLoS One. 2013;8(2):e57086. doi: 10.1371/journal.pone.0057086. Epub 2013 Feb 22.


Ordered phosphorylation events in two independent cascades of the PTEN C-tail revealed by NMR.

Cordier F, Chaffotte A, Terrien E, Préhaud C, Theillet FX, Delepierre M, Lafon M, Buc H, Wolff N.

J Am Chem Soc. 2012 Dec 19;134(50):20533-43. doi: 10.1021/ja310214g. Epub 2012 Dec 7.


Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN.

Terrien E, Chaffotte A, Lafage M, Khan Z, Préhaud C, Cordier F, Simenel C, Delepierre M, Buc H, Lafon M, Wolff N.

Sci Signal. 2012 Aug 14;5(237):ra58. doi: 10.1126/scisignal.2002941.


Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila.

Kubiak X, Dervins-Ravault D, Pluvinage B, Chaffotte AF, Gomez-Valero L, Dairou J, Busi F, Dupret JM, Buchrieser C, Rodrigues-Lima F.

Biochem J. 2012 Jul 15;445(2):219-28. doi: 10.1042/BJ20120528.


Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase.

Nunes GL, Simões A, Dyszy FH, Shida CS, Juliano MA, Juliano L, Gesteira TF, Nader HB, Murphy G, Chaffotte AF, Goldberg ME, Tersariol IL, Almeida PC.

PLoS One. 2011;6(6):e21525. doi: 10.1371/journal.pone.0021525. Epub 2011 Jun 23.


Dynamic aspects of antibody:oligosaccharide complexes characterized by molecular dynamics simulations and saturation transfer difference nuclear magnetic resonance.

Theillet FX, Frank M, Vulliez-Le Normand B, Simenel C, Hoos S, Chaffotte A, Bélot F, Guerreiro C, Nato F, Phalipon A, Mulard LA, Delepierre M.

Glycobiology. 2011 Dec;21(12):1570-9. doi: 10.1093/glycob/cwr059. Epub 2011 May 24.


Carbon black nanoparticles impair acetylation of aromatic amine carcinogens through inactivation of arylamine N-acetyltransferase enzymes.

Sanfins E, Dairou J, Hussain S, Busi F, Chaffotte AF, Rodrigues-Lima F, Dupret JM.

ACS Nano. 2011 Jun 28;5(6):4504-11. doi: 10.1021/nn103534d. Epub 2011 May 3.


Amino acid residues important for folding of thioredoxin are revealed only by study of the physiologically relevant reduced form of the protein.

Huber D, Chaffotte A, Eser M, Planson AG, Beckwith J.

Biochemistry. 2010 Oct 19;49(41):8922-8. doi: 10.1021/bi100784h.


Calcium imaging in single neurons from brain slices using bioluminescent reporters.

Drobac E, Tricoire L, Chaffotte AF, Guiot E, Lambolez B.

J Neurosci Res. 2010 Mar;88(4):695-711. doi: 10.1002/jnr.22249.


Impact of hydrogen peroxide on the activity, structure, and conformational stability of the oxidized protein repair enzyme methionine sulfoxide reductase A.

Le HT, Chaffotte AF, Demey-Thomas E, Vinh J, Friguet B, Mary J.

J Mol Biol. 2009 Oct 16;393(1):58-66. doi: 10.1016/j.jmb.2009.07.072. Epub 2009 Jul 30.


Substrate-induced conformational changes in the essential peripheral membrane-associated mannosyltransferase PimA from mycobacteria: implications for catalysis.

Guerin ME, Schaeffer F, Chaffotte A, Gest P, Giganti D, Korduláková J, van der Woerd M, Jackson M, Alzari PM.

J Biol Chem. 2009 Aug 7;284(32):21613-25. doi: 10.1074/jbc.M109.003947. Epub 2009 Jun 11.


Receptor-binding studies of the DBLgamma domain of Plasmodium falciparum erythrocyte membrane protein 1 from a placental isolate.

Badaut C, Faure G, Tuikue Ndam NG, Bertin G, Chaffotte A, Khattab A, Klinkert MQ, Deloron P, Bentley GA.

Mol Biochem Parasitol. 2007 Jan;151(1):89-99. Epub 2006 Nov 7.


In vitro denaturation-renaturation of fibronectin. Formation of multimers disulfide-linked and shuffling of intramolecular disulfide bonds.

Patel S, Chaffotte AF, Amana B, Goubard F, Pauthe E.

Int J Biochem Cell Biol. 2006;38(9):1547-60. Epub 2006 Mar 28.


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