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Items: 1 to 20 of 53


Silver nanoparticles biosynthesised using Centella asiatica leaf extract: apoptosis induction in MCF-7 breast cancer cell line.

Fard SE, Tafvizi F, Torbati MB.

IET Nanobiotechnol. 2018 Oct;12(7):994-1002. doi: 10.1049/iet-nbt.2018.5069.


Neuroprotective Properties of Asiatic Acid against 5-Fluorouracil Chemotherapy in the Hippocampus in an Adult Rat Model.

Welbat JU, Chaisawang P, Pannangrong W, Wigmore P.

Nutrients. 2018 Aug 9;10(8). pii: E1053. doi: 10.3390/nu10081053.


Anti-cancer activity of asiatic acid against human cholangiocarcinoma cells through inhibition of proliferation and induction of apoptosis.

Sakonsinsiri C, Kaewlert W, Armartmuntree N, Thanan R, Pakdeechote P.

Cell Mol Biol (Noisy-le-grand). 2018 Jul 30;64(10):28-33.


Assessment of Toxicity and Absorption of the Novel AA Derivative AA-Pme in SGC7901 Cancer Cells In Vitro and in Zebrafish In Vivo.

Wang G, Xiao Q, Wu W, Wu Y, Wei Y, Jing Y, Gong Z.

Med Sci Monit. 2018 Aug 4;24:5412-5421. doi: 10.12659/MSM.909606.


Centella asiatica increases hippocampal synaptic density and improves memory and executive function in aged mice.

Gray NE, Zweig JA, Caruso M, Martin MD, Zhu JY, Quinn JF, Soumyanath A.

Brain Behav. 2018 Jul;8(7):e01024. doi: 10.1002/brb3.1024. Epub 2018 Jun 19.


Asiatic acid inhibits proliferation, migration and induces apoptosis by regulating Pdcd4 via the PI3K/Akt/mTOR/p70S6K signaling pathway in human colon carcinoma cells.

Hao Y, Huang J, Ma Y, Chen W, Fan Q, Sun X, Shao M, Cai H.

Oncol Lett. 2018 Jun;15(6):8223-8230. doi: 10.3892/ol.2018.8417. Epub 2018 Apr 4.


Asiatic Acid (AA) Sensitizes Multidrug-Resistant Human Lung Adenocarcinoma A549/DDP Cells to Cisplatin (DDP) via Downregulation of P-Glycoprotein (MDR1) and Its Targets.

Cheng Q, Liao M, Hu H, Li H, Wu L.

Cell Physiol Biochem. 2018;47(1):279-292. doi: 10.1159/000489806. Epub 2018 May 11.


Centella asiatica Attenuates Mitochondrial Dysfunction and Oxidative Stress in Aβ-Exposed Hippocampal Neurons.

Gray NE, Zweig JA, Matthews DG, Caruso M, Quinn JF, Soumyanath A.

Oxid Med Cell Longev. 2017;2017:7023091. doi: 10.1155/2017/7023091. Epub 2017 Aug 13.


Centella asiatica modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC's).

Naidoo DB, Chuturgoon AA, Phulukdaree A, Guruprasad KP, Satyamoorthy K, Sewram V.

BMC Complement Altern Med. 2017 Aug 1;17(1):377. doi: 10.1186/s12906-017-1865-2.


Asiatic acid protects against cognitive deficits and reductions in cell proliferation and survival in the rat hippocampus caused by 5-fluorouracil chemotherapy.

Chaisawang P, Sirichoat A, Chaijaroonkhanarak W, Pannangrong W, Sripanidkulchai B, Wigmore P, Welbat JU.

PLoS One. 2017 Jul 10;12(7):e0180650. doi: 10.1371/journal.pone.0180650. eCollection 2017.


Centella asiatica attenuates Aβ-induced neurodegenerative spine loss and dendritic simplification.

Gray NE, Zweig JA, Murchison C, Caruso M, Matthews DG, Kawamoto C, Harris CJ, Quinn JF, Soumyanath A.

Neurosci Lett. 2017 Apr 12;646:24-29. doi: 10.1016/j.neulet.2017.02.072. Epub 2017 Mar 6.


Asiatic acid inhibits lung cancer cell growth in vitro and in vivo by destroying mitochondria.

Wu T, Geng J, Guo W, Gao J, Zhu X.

Acta Pharm Sin B. 2017 Jan;7(1):65-72. doi: 10.1016/j.apsb.2016.04.003. Epub 2016 Jun 20.


Asiatic acid attenuates pre-neoplastic lesions, oxidative stress, biotransforming enzymes and histopathological alterations in 1,2-dimethylhydrazine-induced experimental rat colon carcinogenesis.

Siddique AI, Mani V, Arivalagan S, Thomas NS, Namasivayam N.

Toxicol Mech Methods. 2017 Feb;27(2):136-150. doi: 10.1080/15376516.2016.1273422. Epub 2017 Jan 11.


Madecassic Acid protects against hypoxia-induced oxidative stress in retinal microvascular endothelial cells via ROS-mediated endoplasmic reticulum stress.

Yang B, Xu Y, Hu Y, Luo Y, Lu X, Tsui CK, Lu L, Liang X.

Biomed Pharmacother. 2016 Dec;84:845-852. doi: 10.1016/j.biopha.2016.10.015. Epub 2016 Oct 8.


Asiatic acid exerts anticancer potential in human ovarian cancer cells via suppression of PI3K/Akt/mTOR signalling.

Ren L, Cao QX, Zhai FR, Yang SQ, Zhang HX.

Pharm Biol. 2016 Nov;54(11):2377-2382. Epub 2016 Mar 17.


Madecassoside suppresses proliferation and invasiveness of HGF-induced human hepatocellular carcinoma cells via PKC-cMET-ERK1/2-COX-2-PGE2 pathway.

Li Z, You K, Li J, Wang Y, Xu H, Gao B, Wang J.

Int Immunopharmacol. 2016 Apr;33:24-32. doi: 10.1016/j.intimp.2016.01.027. Epub 2016 Feb 3.


Oleanane-type triterpene saponins from Hydrocotyle nepalensis.

Ma RJ, Liu ZH, Zi CT, Gao W, Dong FW, Yang L, Li JY, Zhou J, Hu JM.

Fitoterapia. 2016 Apr;110:66-71. doi: 10.1016/j.fitote.2016.02.003. Epub 2016 Feb 2.


Anti-glioma activity and the mechanism of cellular uptake of asiatic acid-loaded solid lipid nanoparticles.

Garanti T, Stasik A, Burrow AJ, Alhnan MA, Wan KW.

Int J Pharm. 2016 Mar 16;500(1-2):305-15. doi: 10.1016/j.ijpharm.2016.01.018. Epub 2016 Jan 13.


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