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Items: 1 to 20 of 34

1.

The 7-phenyl benzoxaborole series is active against Mycobacterium tuberculosis.

Korkegian A, O'Malley T, Xia Y, Zhou Y, Carter DS, Sunde B, Flint L, Thompson D, Ioerger TR, Sacchettini J, Alley MRK, Parish T.

Tuberculosis (Edinb). 2018 Jan;108:96-98. doi: 10.1016/j.tube.2017.11.003. Epub 2017 Nov 7.

2.

Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication.

Deshpande LS, Carter DS, Phillips KF, Blair RE, DeLorenzo RJ.

Neurotoxicology. 2014 Sep;44:17-26. doi: 10.1016/j.neuro.2014.04.006. Epub 2014 Apr 29.

3.

Discovery of N-[4-[6-tert-butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a potent inhibitor of the hepatitis C virus NS5B polymerase.

Talamas FX, Abbot SC, Anand S, Brameld KA, Carter DS, Chen J, Davis D, de Vicente J, Fung AD, Gong L, Harris SF, Inbar P, Labadie SS, Lee EK, Lemoine R, Le Pogam S, Leveque V, Li J, McIntosh J, Nájera I, Park J, Railkar A, Rajyaguru S, Sangi M, Schoenfeld RC, Staben LR, Tan Y, Taygerly JP, Villaseñor AG, Weller PE.

J Med Chem. 2014 Mar 13;57(5):1914-31. doi: 10.1021/jm401329s. Epub 2013 Nov 6.

4.

Characterization of spontaneous recurrent epileptiform discharges in hippocampal-entorhinal cortical slices prepared from chronic epileptic animals.

Carter DS, Deshpande LS, Rafiq A, Sombati S, DeLorenzo RJ.

Seizure. 2011 Apr;20(3):218-24. doi: 10.1016/j.seizure.2010.11.022. Epub 2010 Dec 18.

5.

Preservation of splenic immunocompetence after splenic artery angioembolization for blunt splenic injury.

Malhotra AK, Carter RF, Lebman DA, Carter DS, Riaz OJ, Aboutanos MB, Duane TM, Ivatury RR.

J Trauma. 2010 Nov;69(5):1126-30; discussion 1130-1. doi: 10.1097/TA.0b013e3181f9fa1e.

PMID:
21068617
6.

Design, synthesis, and biological evaluation of new monoamine reuptake inhibitors with potential therapeutic utility in depression and pain.

Lucas MC, Weikert RJ, Carter DS, Cai HY, Greenhouse R, Iyer PS, Lin CJ, Lee EK, Madera AM, Moore A, Ozboya K, Schoenfeld RC, Steiner S, Zhai Y, Lynch SM.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5559-66. doi: 10.1016/j.bmcl.2010.07.020. Epub 2010 Aug 4.

PMID:
20691589
7.

Outcomes following temporal bone resection.

Dean NR, White HN, Carter DS, Desmond RA, Carroll WR, McGrew BM, Rosenthal EL.

Laryngoscope. 2010 Aug;120(8):1516-22. doi: 10.1002/lary.20999.

8.

Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus.

Nagarkatti N, Deshpande LS, Carter DS, DeLorenzo RJ.

Eur J Neurosci. 2010 Jul;32(1):80-8. doi: 10.1111/j.1460-9568.2010.07262.x. Epub 2010 Jun 28.

9.

2-Substituted N-aryl piperazines as novel triple reuptake inhibitors for the treatment of depression.

Carter DS, Cai HY, Lee EK, Iyer PS, Lucas MC, Roetz R, Schoenfeld RC, Weikert RJ.

Bioorg Med Chem Lett. 2010 Jul 1;20(13):3941-5. doi: 10.1016/j.bmcl.2010.05.008. Epub 2010 May 10.

PMID:
20570146
10.

Development of a prolonged calcium plateau in hippocampal neurons in rats surviving status epilepticus induced by the organophosphate diisopropylfluorophosphate.

Deshpande LS, Carter DS, Blair RE, DeLorenzo RJ.

Toxicol Sci. 2010 Aug;116(2):623-31. doi: 10.1093/toxsci/kfq157. Epub 2010 May 23.

11.

Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist.

Brotherton-Pleiss CE, Dillon MP, Ford AP, Gever JR, Carter DS, Gleason SK, Lin CJ, Moore AG, Thompson AW, Villa M, Zhai Y.

Bioorg Med Chem Lett. 2010 Feb 1;20(3):1031-6. doi: 10.1016/j.bmcl.2009.12.044. Epub 2009 Dec 16.

PMID:
20045645
12.

Novel, achiral aminoheterocycles as selective monoamine reuptake inhibitors.

Lucas MC, Carter DS, Cai HY, Lee EK, Schoenfeld RC, Steiner S, Villa M, Weikert RJ, Iyer PS.

Bioorg Med Chem Lett. 2009 Aug 15;19(16):4630-3. doi: 10.1016/j.bmcl.2009.06.076. Epub 2009 Jun 25.

PMID:
19592243
13.

Temporal characterization of changes in hippocampal cannabinoid CB(1) receptor expression following pilocarpine-induced status epilepticus.

Falenski KW, Carter DS, Harrison AJ, Martin BR, Blair RE, DeLorenzo RJ.

Brain Res. 2009 Mar 25;1262:64-72. doi: 10.1016/j.brainres.2009.01.036. Epub 2009 Jan 31.

14.

Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.

Carter DS, Alam M, Cai H, Dillon MP, Ford AP, Gever JR, Jahangir A, Lin C, Moore AG, Wagner PJ, Zhai Y.

Bioorg Med Chem Lett. 2009 Mar 15;19(6):1628-31. doi: 10.1016/j.bmcl.2009.02.003. Epub 2009 Feb 7.

PMID:
19231180
15.

Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.

Jahangir A, Alam M, Carter DS, Dillon MP, Bois DJ, Ford AP, Gever JR, Lin C, Wagner PJ, Zhai Y, Zira J.

Bioorg Med Chem Lett. 2009 Mar 15;19(6):1632-5. doi: 10.1016/j.bmcl.2009.01.097. Epub 2009 Feb 4.

PMID:
19231178
16.

Novel 3,3-disubstituted pyrrolidines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors.

Bannwart LM, Carter DS, Cai HY, Choy JC, Greenhouse R, Jaime-Figueroa S, Iyer PS, Lin CJ, Lee EK, Lucas MC, Lynch SM, Madera AM, Moore A, Ozboya K, Raptova L, Roetz R, Schoenfeld RC, Stein KA, Steiner S, Villa M, Weikert RJ, Zhai Y.

Bioorg Med Chem Lett. 2008 Dec 1;18(23):6062-6. doi: 10.1016/j.bmcl.2008.10.025. Epub 2008 Oct 11.

PMID:
18954985
17.

Long-term decrease in calbindin-D28K expression in the hippocampus of epileptic rats following pilocarpine-induced status epilepticus.

Carter DS, Harrison AJ, Falenski KW, Blair RE, DeLorenzo RJ.

Epilepsy Res. 2008 May;79(2-3):213-23. doi: 10.1016/j.eplepsyres.2008.02.006. Epub 2008 Apr 3.

18.

Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons.

Raza M, Deshpande LS, Blair RE, Carter DS, Sombati S, DeLorenzo RJ.

Neurosci Lett. 2007 May 11;418(1):77-81. Epub 2007 Mar 12.

19.

Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy.

Deshpande LS, Sombati S, Blair RE, Carter DS, Martin BR, DeLorenzo RJ.

Neurosci Lett. 2007 Jan 3;411(1):11-6. Epub 2006 Nov 15.

20.

Altered calcium/calmodulin kinase II activity changes calcium homeostasis that underlies epileptiform activity in hippocampal neurons in culture.

Carter DS, Haider SN, Blair RE, Deshpande LS, Sombati S, DeLorenzo RJ.

J Pharmacol Exp Ther. 2006 Dec;319(3):1021-31. Epub 2006 Sep 13.

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