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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 3
1982 5
1983 9
1984 14
1985 29
1986 46
1987 80
1988 88
1989 97
1990 86
1991 92
1992 88
1993 92
1994 83
1995 78
1996 66
1997 63
1998 61
1999 66
2000 38
2001 29
2002 31
2003 28
2004 39
2005 35
2006 55
2007 40
2008 57
2009 72
2010 43
2011 67
2012 85
2013 74
2014 97
2015 99
2016 89
2017 83
2018 117
2019 142
2020 172
2021 174
2022 203
2023 170
2024 47

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2,996 results

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Page 1
Csf1 from marrow adipogenic precursors is required for osteoclast formation and hematopoiesis in bone.
Zhong L, Lu J, Fang J, Yao L, Yu W, Gui T, Duffy M, Holdreith N, Bautista CA, Huang X, Bandyopadhyay S, Tan K, Chen C, Choi Y, Jiang JX, Yang S, Tong W, Dyment N, Qin L. Zhong L, et al. Elife. 2023 Feb 13;12:e82112. doi: 10.7554/eLife.82112. Elife. 2023. PMID: 36779854 Free PMC article.
In comparison, depletion of Csf1 in the entire mesenchymal lineage using Prrx1(Cre) led to a more striking high bone mass phenotype, suggesting that additional mesenchymal subpopulations secrete Csf1. ...Moreover, Csf1 CKO(Adipoq) mice were resistant to LPS-i …
In comparison, depletion of Csf1 in the entire mesenchymal lineage using Prrx1(Cre) led to a more striking high bone mass phenotype, …
Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair.
Sehgal A, Irvine KM, Hume DA. Sehgal A, et al. Semin Immunol. 2021 Apr;54:101509. doi: 10.1016/j.smim.2021.101509. Epub 2021 Nov 4. Semin Immunol. 2021. PMID: 34742624 Review.
Cell-specific deletion of a floxed Csf1 allele in mice indicates that local CSF1 production contributes to the maintenance of tissue-specific macrophage populations but is not saturating. ...We suggest that CSF1 has therapeutic potential in regenerative medic …
Cell-specific deletion of a floxed Csf1 allele in mice indicates that local CSF1 production contributes to the maintenance of …
Increased expression of CSF1 in patients with eosinophilic asthma.
Du L, Tang L, Xiao L, Tang K, Zeng Z, Liang Y, Guo Y. Du L, et al. Immun Inflamm Dis. 2023 May;11(5):e847. doi: 10.1002/iid3.847. Immun Inflamm Dis. 2023. PMID: 37249291 Free PMC article.
BACKGROUND: The link between colony-stimulating factor 1 (CSF1) and asthma was reported recently. However, the role and mechanism of CSF1 in asthma remain poorly understood. ...In vitro, cytokines interleukin 13 (IL-13) and IL-33 can stimulate the upregulation of …
BACKGROUND: The link between colony-stimulating factor 1 (CSF1) and asthma was reported recently. However, the role and mechanism of …
CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization.
Zhou Y, Zeng J, Tu Y, Li L, Du S, Zhu L, Cang X, Lu J, Zhu M, Liu X. Zhou Y, et al. Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):37. doi: 10.1167/iovs.62.3.37. Invest Ophthalmol Vis Sci. 2021. PMID: 33764399 Free PMC article.
Human macrophages promoted the proliferation, migration, and tube formation of HCVECs in a CSF1/CSFR1-dependent manner under hypoxic conditions. CSF1/CSF1R blockade ameliorated the formation of mouse laser-induced CNV. CSF1 and CSF1R were increased in the aqu …
Human macrophages promoted the proliferation, migration, and tube formation of HCVECs in a CSF1/CSFR1-dependent manner under hypoxic …
Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy.
Cannarile MA, Weisser M, Jacob W, Jegg AM, Ries CH, Rüttinger D. Cannarile MA, et al. J Immunother Cancer. 2017 Jul 18;5(1):53. doi: 10.1186/s40425-017-0257-y. J Immunother Cancer. 2017. PMID: 28716061 Free PMC article. Review.
We review the currently available clinical safety and efficacy data with CSF1/CSF1R-targeting agents and provide a comprehensive overview of ongoing clinical studies. Furthermore, we discuss the local tissue macrophage and tumor-type specificities and their potential impac …
We review the currently available clinical safety and efficacy data with CSF1/CSF1R-targeting agents and provide a comprehensive over …
Important oncogenic and immunogenic roles of SPP1 and CSF1 in hepatocellular carcinoma.
Xiang T, Cheng N, Huang B, Zhang X, Zeng P. Xiang T, et al. Med Oncol. 2023 Apr 25;40(6):158. doi: 10.1007/s12032-023-02024-7. Med Oncol. 2023. PMID: 37097499 Free PMC article.
Therefore, this study analyzed the oncogenic and immunologic roles of SPP1 and CSF1 in hepatocellular carcinoma (HCC). We found that the expression levels of SPP1 and CSF1 in HCC were markedly increased and positively correlated. ...Finally, we demonstrated the onco …
Therefore, this study analyzed the oncogenic and immunologic roles of SPP1 and CSF1 in hepatocellular carcinoma (HCC). We found that …
Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment.
Maldonado MDM, Schlom J, Hamilton DH. Maldonado MDM, et al. Cancer Immunol Immunother. 2023 Oct;72(10):3349-3362. doi: 10.1007/s00262-023-03496-2. Epub 2023 Jul 28. Cancer Immunol Immunother. 2023. PMID: 37505292 Free PMC article.
In addition to its essential physiological role in normal tissues, the CSF1/CSF1 receptor axis is known to be overexpressed in many tumor types and associated with poor prognosis. ...The combination of neoepitope vaccine with anti-PDL1 in the MC38 CSF1-/- tum …
In addition to its essential physiological role in normal tissues, the CSF1/CSF1 receptor axis is known to be overexpressed in …
CSF1/CSF1R Axis Blockade Limits Mesothelioma and Enhances Efficiency of Anti-PDL1 Immunotherapy.
Magkouta SF, Vaitsi PC, Pappas AG, Iliopoulou M, Kosti CN, Psarra K, Kalomenidis IT. Magkouta SF, et al. Cancers (Basel). 2021 May 22;13(11):2546. doi: 10.3390/cancers13112546. Cancers (Basel). 2021. PMID: 34067348 Free PMC article.
We hypothesized that CSF1/CSF1R inhibition would halt mesothelioma growth by targeting immunosuppressive M2 macrophages and unleashing efficient T cell responses. We also hypothesized that CSF1/CSF1R blockade would enhance the efficacy of a PDL1 inhibitor which dire …
We hypothesized that CSF1/CSF1R inhibition would halt mesothelioma growth by targeting immunosuppressive M2 macrophages and unleashin …
Mesothelial cell CSF1 sustains peritoneal macrophage proliferation.
Ivanov S, Gallerand A, Gros M, Stunault MI, Merlin J, Vaillant N, Yvan-Charvet L, Guinamard RR. Ivanov S, et al. Eur J Immunol. 2019 Nov;49(11):2012-2018. doi: 10.1002/eji.201948164. Epub 2019 Jul 5. Eur J Immunol. 2019. PMID: 31251389 Free article.
These cells presumably require and interact with the omentum, where milky spot stromal cells have been proposed to secrete CSF1 (colony stimulating factor 1). Peritoneal macrophages depend on CSF1 for their generation and survival, but the identity of CSF1 pr …
These cells presumably require and interact with the omentum, where milky spot stromal cells have been proposed to secrete CSF1 (colo …
Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche.
Emoto T, Lu J, Sivasubramaniyam T, Maan H, Khan AB, Abow AA, Schroer SA, Hyduk SJ, Althagafi MG, McKee TD, Fu F, Shabro S, Ulndreaj A, Chiu F, Paneda E, Pacheco S, Wang T, Li A, Jiang JX, Libby P, Husain M, Wang B, Rubin BB, Cybulsky MI, Robbins CS. Emoto T, et al. Immunity. 2022 May 10;55(5):862-878.e8. doi: 10.1016/j.immuni.2022.04.005. Epub 2022 May 3. Immunity. 2022. PMID: 35508166 Free article.
Indeed, we show here that osteolineage-derived Csf1 prevented developmental abnormalities but had no effect on monopoiesis in adulthood. ...Bone histology revealed that monocytes reside near sinusoidal endothelial cells (ECs) and leptin receptor (Lepr)-expressing perivascu …
Indeed, we show here that osteolineage-derived Csf1 prevented developmental abnormalities but had no effect on monopoiesis in adultho …
2,996 results