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CLA does not impair endothelial function and decreases body weight as compared with safflower oil in overweight and obese male subjects.
Pfeuffer M, Fielitz K, Laue C, Winkler P, Rubin D, Helwig U, Giller K, Kammann J, Schwedhelm E, Böger RH, Bub A, Bell D, Schrezenmeir J. Pfeuffer M, et al. J Am Coll Nutr. 2011 Feb;30(1):19-28. doi: 10.1080/07315724.2011.10719940. J Am Coll Nutr. 2011. PMID: 21697535 Clinical Trial.
Heated safflower oil and olive oil were given for additional descriptive control. METHODS: Eighty-five overweight men (aged 45-68 years, body mass index 25-35 kg/m(2)) were randomized to receive 4.5 g/d of the CLA isomeric mixture, safflower …
Heated safflower oil and olive oil were given for additional descriptive control. METHODS: Eighty-five overweight men ( …
Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus.
Norris LE, Collene AL, Asp ML, Hsu JC, Liu LF, Richardson JR, Li D, Bell D, Osei K, Jackson RD, Belury MA. Norris LE, et al. Am J Clin Nutr. 2009 Sep;90(3):468-76. doi: 10.3945/ajcn.2008.27371. Epub 2009 Jun 17. Am J Clin Nutr. 2009. PMID: 19535429 Free PMC article. Clinical Trial.
BACKGROUND: Weight loss may improve glucose control in persons with type 2 diabetes. The effects of fat quality, as opposed to quantity, on weight loss are not well understood. OBJECTIVE: We compared the effects of 2 dietary oils, conjugated linoleic a …
BACKGROUND: Weight loss may improve glucose control in persons with type 2 diabetes. The effects of fat quality, as opposed to …
Conjugated docosahexaenoic acid inhibits lipid accumulation in rats.
Tsuzuki T, Kawakami Y, Nakagawa K, Miyazawa T. Tsuzuki T, et al. J Nutr Biochem. 2006 Aug;17(8):518-24. doi: 10.1016/j.jnutbio.2005.09.006. Epub 2005 Oct 25. J Nutr Biochem. 2006. PMID: 16426831
Conjugated linoleic acid (CLA), which contains a conjugated double-bond system, and n-3 highly unsaturated fatty acids such as docosahexaenoic acid (DHA) are widely known to improve lipid metabolism. ...Rats were force fed with 200 mg of test oils [linoleic acid (LA), DHA, …
Conjugated linoleic acid (CLA), which contains a conjugated double-bond system, and n-3 highly unsaturated fatty acids such as docosa …
Trans-8, cis-10+ cis-9, trans-11-conjugated linoleic acid mixture alters body composition in Syrian golden hamsters fed a hypercholesterolaemic diet.
Joseph SV, Liu X, Wakefield A, Chouinard PY, Aukema H, Jones PJ, Jacques H. Joseph SV, et al. Br J Nutr. 2010 Nov;104(10):1443-9. doi: 10.1017/S0007114510002345. Epub 2010 Jul 8. Br J Nutr. 2010. PMID: 20609266
The effectiveness of conjugated linoleic acid (CLA) as a weight-loss nutraceutical continues to be debatable, suggesting that there may be value in exploring the physiological effects of the lesser-known isomers. ...Animals were randomised to receive for 28 d …
The effectiveness of conjugated linoleic acid (CLA) as a weight-loss nutraceutical continues to be debatable, suggestin …
Effects of conjugated linoleic acid and exercise on bone mass in young male Balb/C mice.
Banu J, Bhattacharya A, Rahman M, O'Shea M, Fernandes G. Banu J, et al. Lipids Health Dis. 2006 Mar 23;5:7. doi: 10.1186/1476-511X-5-7. Lipids Health Dis. 2006. PMID: 16556311 Free PMC article.
There is an increase in obesity among the population of industrialized countries, and dietary supplementation with Conjugated Linoleic Acid (CLA) has been reported to lower body fat mass. However, weight loss is generally associated with negative effects on b …
There is an increase in obesity among the population of industrialized countries, and dietary supplementation with Conjugated Linoleic Acid …
Supplemental conjugated linoleic acid consumption does not influence milk macronutrient contents in all healthy lactating women.
Mosley SA, Shahin AM, Williams J, McGuire MA, McGuire MK. Mosley SA, et al. Lipids. 2007 Aug;42(8):723-9. doi: 10.1007/s11745-007-3087-8. Epub 2007 Jul 4. Lipids. 2007. PMID: 17610100 Clinical Trial.
Due to the array of putative benefits associated with various forms of CLA, there has been recent interest in supplementing human diets with these fatty acids especially when weight loss is desired. ...Breastfeeding women (n = 12) were assigned randomly to tr …
Due to the array of putative benefits associated with various forms of CLA, there has been recent interest in supplementing human die …
Conjugated Linoleic Acid Administration Induces Amnesia in Male Sprague Dawley Rats and Exacerbates Recovery from Functional Deficits Induced by a Controlled Cortical Impact Injury.
Geddes RI, Hayashi K, Bongers Q, Wehber M, Anderson IM, Jansen AD, Nier C, Fares E, Farquhar G, Kapoor A, Ziegler TE, VadakkadathMeethal S, Bird IM, Atwood CS. Geddes RI, et al. PLoS One. 2017 Jan 26;12(1):e0169494. doi: 10.1371/journal.pone.0169494. eCollection 2017. PLoS One. 2017. PMID: 28125600 Free PMC article.
To test the impact of CLA on cognitive recovery following a TBI, 5-6 month old male Sprague Dawley rats received a focal injury (craniectomy + controlled cortical impact (CCI; n = 17)) or Sham injury (craniectomy alone; n = 12) and were injected with 25 mg/kg body weigh …
To test the impact of CLA on cognitive recovery following a TBI, 5-6 month old male Sprague Dawley rats received a focal injury (cran …
Moderate doses of conjugated linoleic acid isomers mix contribute to lowering body fat content maintaining insulin sensitivity and a noninflammatory pattern in adipose tissue in mice.
Parra P, Serra F, Palou A. Parra P, et al. J Nutr Biochem. 2010 Feb;21(2):107-15. doi: 10.1016/j.jnutbio.2008.10.010. Epub 2009 Feb 5. J Nutr Biochem. 2010. PMID: 19195867
Mice were orally treated with a mixture of CLA isomers, cis-9,trans-11 and trans-10,cis-12 (50:50), for 35 days with doses of CLA1 (0.15 g CLA/kg body weight) and CLA2 (0.5 g CLA/kg body weight). CLA had discrete effects on body weight …
Mice were orally treated with a mixture of CLA isomers, cis-9,trans-11 and trans-10,cis-12 (50:50), for 35 days with doses of CLA1 (0 …