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Items: 4


CK-2127107 amplifies skeletal muscle response to nerve activation in humans.

Andrews JA, Miller TM, Vijayakumar V, Stoltz R, James JK, Meng L, Wolff AA, Malik FI.

Muscle Nerve. 2018 May;57(5):729-734. doi: 10.1002/mus.26017. Epub 2017 Dec 11.


The COPD Pipeline XXXII.

Gross N.

Chronic Obstr Pulm Dis. 2016 Jul 14;3(3):688-692. doi: 10.15326/jcopdf.3.3.2016.0150. No abstract available.


Small Molecules in Development for the Treatment of Spinal Muscular Atrophy.

Calder AN, Androphy EJ, Hodgetts KJ.

J Med Chem. 2016 Nov 23;59(22):10067-10083. Epub 2016 Aug 16. Review.


The small-molecule fast skeletal troponin activator, CK-2127107, improves exercise tolerance in a rat model of heart failure.

Hwee DT, Kennedy AR, Hartman JJ, Ryans J, Durham N, Malik FI, Jasper JR.

J Pharmacol Exp Ther. 2015 Apr;353(1):159-68. doi: 10.1124/jpet.114.222224. Epub 2015 Feb 12.

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