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MANF is Required for the Postnatal Expansion and Maintenance of the Pancreatic β-Cell Mass in Mice.

Danilova T, Belevich I, Li H, Palm E, Jokitalo E, Otonkoski T, Lindahl M.

Diabetes. 2018 Oct 10. pii: db171149. doi: 10.2337/db17-1149. [Epub ahead of print]


p58IPK Is an Endogenous Neuroprotectant for Retinal Ganglion Cells.

McLaughlin T, Dhimal N, Li J, Wang JJ, Zhang SX.

Front Aging Neurosci. 2018 Sep 7;10:267. doi: 10.3389/fnagi.2018.00267. eCollection 2018.


Antioxidative CXXC Peptide Motif From Mesencephalic Astrocyte-Derived Neurotrophic Factor Antagonizes Programmed Cell Death.

Božok V, Yu LY, Palgi J, Arumäe U.

Front Cell Dev Biol. 2018 Sep 4;6:106. doi: 10.3389/fcell.2018.00106. eCollection 2018.


Mesencephalic astrocyte-derived neurotrophic factor affords neuroprotection to early brain injury induced by subarachnoid hemorrhage via activating Akt-dependent prosurvival pathway and defending blood-brain barrier integrity.

Li T, Xu W, Gao L, Guan G, Zhang Z, He P, Xu H, Fan L, Yan F, Chen G.

FASEB J. 2018 Sep 13:fj201800227RR. doi: 10.1096/fj.201800227RR. [Epub ahead of print]


C. elegans MANF Homolog Is Necessary for the Protection of Dopaminergic Neurons and ER Unfolded Protein Response.

Richman C, Rashid S, Prashar S, Mishra R, Selvaganapathy PR, Gupta BP.

Front Neurosci. 2018 Aug 10;12:544. doi: 10.3389/fnins.2018.00544. eCollection 2018.


The transcriptome of the rat subfornical organ is altered in response to early postnatal overnutrition.

Peterson CS, Huang S, Lee SA, Ferguson AV, Fry WM.

IBRO Rep. 2018 Jun 26;5:17-23. doi: 10.1016/j.ibror.2018.06.001. eCollection 2018 Dec.


Trophic factors for Parkinson's disease: Where are we and where do we go from here?

Paul G, Sullivan AM.

Eur J Neurosci. 2018 Aug 13. doi: 10.1111/ejn.14102. [Epub ahead of print] Review.


Endoplasmic reticulum stress and monogenic kidney diseases in precision nephrology.

Park SJ, Kim Y, Chen YM.

Pediatr Nephrol. 2018 Aug 11. doi: 10.1007/s00467-018-4031-2. [Epub ahead of print] Review.


MANF protects human pancreatic beta cells against stress-induced cell death.

Hakonen E, Chandra V, Fogarty CL, Yu NY, Ustinov J, Katayama S, Galli E, Danilova T, Lindholm P, Vartiainen A, Einarsdottir E, Krjutškov K, Kere J, Saarma M, Lindahl M, Otonkoski T.

Diabetologia. 2018 Oct;61(10):2202-2214. doi: 10.1007/s00125-018-4687-y. Epub 2018 Jul 21.


Perfluorododecanoic acid exposure induced developmental neurotoxicity in zebrafish embryos.

Guo X, Zhang S, Lu S, Zheng B, Xie P, Chen J, Li G, Liu C, Wu Q, Cheng H, Sang N.

Environ Pollut. 2018 Oct;241:1018-1026. doi: 10.1016/j.envpol.2018.06.013. Epub 2018 Jun 8.


Aberrant Promoter Methylation of YAP Gene and its Subsequent Downregulation in Indian Breast Cancer Patients.

Real SAS, Parveen F, Rehman AU, Khan MA, Deo SVS, Shukla NK, Husain SA.

BMC Cancer. 2018 Jul 3;18(1):711. doi: 10.1186/s12885-018-4627-8.


Cerebral Dopamine Neurotrophic Factor (CDNF) Has Neuroprotective Effects against Cerebral Ischemia That May Occur through the Endoplasmic Reticulum Stress Pathway.

Zhang GL, Wang LH, Liu XY, Zhang YX, Hu MY, Liu L, Fang YY, Mu Y, Zhao Y, Huang SH, Liu T, Wang XJ.

Int J Mol Sci. 2018 Jun 29;19(7). pii: E1905. doi: 10.3390/ijms19071905.


MANF protects dopamine neurons and locomotion defects from a human α-synuclein induced Parkinson's disease model in C. elegans by regulating ER stress and autophagy pathways.

Zhang Z, Shen Y, Luo H, Zhang F, Jing L, Wu Y, Xia X, Song Y, Li W, Jin L.

Exp Neurol. 2018 Oct;308:59-71. doi: 10.1016/j.expneurol.2018.06.016. Epub 2018 Jun 28.


Quorum sensing in thermophiles: prevalence of autoinducer-2 system.

Kaur A, Capalash N, Sharma P.

BMC Microbiol. 2018 Jun 28;18(1):62. doi: 10.1186/s12866-018-1204-x.


Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Protects Against Neuronal Apoptosis via Activation of Akt/MDM2/p53 Signaling Pathway in a Rat Model of Intracerebral Hemorrhage.

Xu W, Gao L, Li T, Zheng J, Shao A, Zhang J.

Front Mol Neurosci. 2018 May 29;11:176. doi: 10.3389/fnmol.2018.00176. eCollection 2018.


MANF improves the MPP+/MPTP-induced Parkinson's disease via improvement of mitochondrial function and inhibition of oxidative stress.

Liu Y, Zhang J, Jiang M, Cai Q, Fang J, Jin L.

Am J Transl Res. 2018 May 15;10(5):1284-1294. eCollection 2018.


Mesencephalic Astrocyte-Derived Neurotrophic Factor Prevents Traumatic Brain Injury in Rats by Inhibiting Inflammatory Activation and Protecting the Blood-Brain Barrier.

Li QX, Shen YX, Ahmad A, Shen YJ, Zhang YQ, Xu PK, Chen WW, Yu YQ.

World Neurosurg. 2018 Sep;117:e117-e129. doi: 10.1016/j.wneu.2018.05.202. Epub 2018 Jun 5.


Application of NanoBiT for Monitoring Dimerization of the Null Hong Kong Variant of α-1-Antitrypsin, NHK, in Living Cells.

Norisada J, Fujimura K, Amaya F, Kohno H, Hirata Y, Oh-Hashi K.

Mol Biotechnol. 2018 Jun 6. doi: 10.1007/s12033-018-0092-5. [Epub ahead of print]


Disease Modification Through Trophic Factor Delivery.

Savolainen M, Emerich D, Kordower JH.

Methods Mol Biol. 2018;1780:525-547. doi: 10.1007/978-1-4939-7825-0_24.


Poststroke delivery of MANF promotes functional recovery in rats.

Mätlik K, Anttila JE, Kuan-Yin T, Smolander OP, Pakarinen E, Lehtonen L, Abo-Ramadan U, Lindholm P, Zheng C, Harvey B, Arumäe U, Lindahl M, Airavaara M.

Sci Adv. 2018 May 23;4(5):eaap8957. doi: 10.1126/sciadv.aap8957. eCollection 2018 May.

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