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Porcine CD83 is a glycosylated dimeric protein existing naturally in membrane-bound and soluble forms.

Huo S, Zhang J, Wu F, Zuo Y, Cui D, Li X, Zhong Z, Zhong F.

Dev Comp Immunol. 2018 Sep 5;90:60-69. doi: 10.1016/j.dci.2018.09.002. [Epub ahead of print]


Soluble CD83 Alleviates Experimental Autoimmune Uveitis by Inhibiting Filamentous Actin-Dependent Calcium Release in Dendritic Cells.

Lin W, Buscher K, Wang B, Fan Z, Song N, Li P, Yue Y, Li B, Li C, Bi H.

Front Immunol. 2018 Jul 9;9:1567. doi: 10.3389/fimmu.2018.01567. eCollection 2018.


Reduction of CD83 Expression on B Cells and the Genetic Basis for Rheumatoid Arthritis: Comment on the Article by Thalayasingam et al.

Tsuchida Y, Sumitomo S, Ota M, Tsuchiya H, Nagafuchi Y, Shoda H, Fujio K, Ishigaki K, Yamaguchi K, Suzuki A, Kochi Y, Yamamoto K.

Arthritis Rheumatol. 2018 Oct;70(10):1695-1696. doi: 10.1002/art.40652. No abstract available.


CD83 expression is essential for Treg cell differentiation and stability.

Doebbeler M, Koenig C, Krzyzak L, Seitz C, Wild A, Ulas T, Baßler K, Kopelyanskiy D, Butterhof A, Kuhnt C, Kreiser S, Stich L, Zinser E, Knippertz I, Wirtz S, Riegel C, Hoffmann P, Edinger M, Nitschke L, Winkler T, Schultze JL, Steinkasserer A, Lechmann M.

JCI Insight. 2018 Jun 7;3(11). pii: 99712. doi: 10.1172/jci.insight.99712. [Epub ahead of print]


Nsp1α of Porcine Reproductive and Respiratory Syndrome Virus Strain BB0907 Impairs the Function of Monocyte-Derived Dendritic Cells via the Release of Soluble CD83.

Chen X, Bai J, Liu X, Song Z, Zhang Q, Wang X, Jiang P.

J Virol. 2018 Jul 17;92(15). pii: e00366-18. doi: 10.1128/JVI.00366-18. Print 2018 Aug 1.


The levels of soluble forms of CD21 and CD83 in multiple sclerosis.

Karampoor S, Zahednasab H, Etemadifar M, Keyvani H.

J Neuroimmunol. 2018 Jul 15;320:11-14. doi: 10.1016/j.jneuroim.2018.04.005. Epub 2018 Apr 13.


CD83 Antibody Inhibits Human B Cell Responses to Antigen as well as Dendritic Cell-Mediated CD4 T Cell Responses.

Wong KY, Baron R, Seldon TA, Jones ML, Rice AM, Munster DJ.

J Immunol. 2018 May 15;200(10):3383-3396. doi: 10.4049/jimmunol.1700064. Epub 2018 Apr 11.


CD83 in Hodgkin lymphoma.

Küppers R.

Haematologica. 2018 Apr;103(4):561-562. doi: 10.3324/haematol.2018.188870. No abstract available.


CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma.

Li Z, Ju X, Lee K, Clarke C, Hsu JL, Abadir E, Bryant CE, Pears S, Sunderland N, Heffernan S, Hennessy A, Lo TH, Pietersz GA, Kupresanin F, Fromm PD, Silveira PA, Tsonis C, Cooper WA, Cunningham I, Brown C, Clark GJ, Hart DNJ.

Haematologica. 2018 Apr;103(4):655-665. doi: 10.3324/haematol.2017.178384. Epub 2018 Jan 19.


Acquired Protective Immunity in Atlantic Salmon Salmo salar against the Myxozoan Kudoa thyrsites Involves Induction of MHIIβ+ CD83+ Antigen-Presenting Cells.

Braden LM, Rasmussen KJ, Purcell SL, Ellis L, Mahony A, Cho S, Whyte SK, Jones SRM, Fast MD.

Infect Immun. 2017 Dec 19;86(1). pii: e00556-17. doi: 10.1128/IAI.00556-17. Print 2018 Jan.


The Nucleocapsid Protein and Nonstructural Protein 10 of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Enhance CD83 Production via NF-κB and Sp1 Signaling Pathways.

Chen X, Zhang Q, Bai J, Zhao Y, Wang X, Wang H, Jiang P.

J Virol. 2017 Aug 24;91(18). pii: e00986-17. doi: 10.1128/JVI.00986-17. Print 2017 Sep 15.


Characterization and expression analysis of grouper (Epinephelus coioides) co-stimulatory molecules CD83 and CD80/86 post Cryptocaryon irritans infection.

Mo ZQ, Wang JL, Yang M, Ni LY, Wang HQ, Lao GF, Li YW, Li AX, Luo XC, Dan XM.

Fish Shellfish Immunol. 2017 Aug;67:467-474. doi: 10.1016/j.fsi.2017.05.064. Epub 2017 Jun 1.


A Kinetic Study of CD83 Reveals an Upregulation and Higher Production of sCD83 in Lymphocytes from Pregnant Mice.

Packhäuser KRH, Roman-Sosa G, Ehrhardt J, Krüger D, Zygmunt M, Muzzio DO.

Front Immunol. 2017 Apr 26;8:486. doi: 10.3389/fimmu.2017.00486. eCollection 2017.


Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83.

Heilingloh CS, Klingl S, Egerer-Sieber C, Schmid B, Weiler S, Mühl-Zürbes P, Hofmann J, Stump JD, Sticht H, Kummer M, Steinkasserer A, Muller YA.

J Mol Biol. 2017 Apr 21;429(8):1227-1243. doi: 10.1016/j.jmb.2017.03.009. Epub 2017 Mar 15.


Expression of soluble CD83 in plasma from early-stage rheumatoid arthritis patients is not modified by anti-TNF-α therapy.

Kristensen AM, Stengaard-Pedersen K, Hetland ML, Hørslev-Petersen K, Junker P, Østergaard M, Höllsberg P, Deleuran B, Hvid M.

Cytokine. 2017 Aug;96:1-7. doi: 10.1016/j.cyto.2017.02.017. Epub 2017 Mar 6.


The Major Immediate-Early Protein IE2 of Human Cytomegalovirus Is Sufficient to Induce Proteasomal Degradation of CD83 on Mature Dendritic Cells.

Heilingloh CS, Grosche L, Kummer M, Mühl-Zürbes P, Kamm L, Scherer M, Latzko M, Stamminger T, Steinkasserer A.

Front Microbiol. 2017 Feb 1;8:119. doi: 10.3389/fmicb.2017.00119. eCollection 2017.


Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes.

Horvatinovich JM, Grogan EW, Norris M, Steinkasserer A, Lemos H, Mellor AL, Tcherepanova IY, Nicolette CA, DeBenedette MA.

J Immunol. 2017 Mar 15;198(6):2286-2301. doi: 10.4049/jimmunol.1600802. Epub 2017 Feb 13.


The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population.

Ju X, Silveira PA, Hsu WH, Elgundi Z, Alingcastre R, Verma ND, Fromm PD, Hsu JL, Bryant C, Li Z, Kupresanin F, Lo TH, Clarke C, Lee K, McGuire H, Fazekas de St Groth B, Larsen SR, Gibson J, Bradstock KF, Clark GJ, Hart DN.

J Immunol. 2016 Dec 15;197(12):4613-4625. Epub 2016 Nov 11.


Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83.

von Rohrscheidt J, Petrozziello E, Nedjic J, Federle C, Krzyzak L, Ploegh HL, Ishido S, Steinkasserer A, Klein L.

J Exp Med. 2016 Aug 22;213(9):1685-94. doi: 10.1084/jem.20160316. Epub 2016 Aug 8.


Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection.

Liu H, Jain R, Guan J, Vuong V, Ishido S, La Gruta NL, Gray DH, Villadangos JA, Mintern JD.

J Exp Med. 2016 Aug 22;213(9):1695-703. doi: 10.1084/jem.20160312. Epub 2016 Aug 8.

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