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In IgA Nephropathy, Glomerulosclerosis Is Associated with Increased Urinary CD80 Excretion and Urokinase-Type Plasminogen Activator Receptor-Positive Podocyturia.

Trimarchi H, Canzonieri R, Schiel A, Costales-Collaguazo C, Stern A, Paulero M, Rengel T, Andrews J, Iotti A, Forrester M, Lombi F, Pomeranz V, Iriarte R, Muryan A, Zotta E.

Nephron Extra. 2017 May 16;7(2):52-61. doi: 10.1159/000473888. eCollection 2017 May-Aug.


Characterization and expression analysis of grouper (Epinephelus coioides) co-stimulatory molecules CD83 and CD80/86 post Cryptocaryon irritans infection.

Mo ZQ, Wang JL, Yang M, Ni LY, Wang HQ, Lao GF, Li YW, Li AX, Luo XC, Dan XM.

Fish Shellfish Immunol. 2017 Jun 1. pii: S1050-4648(17)30316-9. doi: 10.1016/j.fsi.2017.05.064. [Epub ahead of print]


Adiponectin inhibits oxidization-induced differentiation of T helper cells through inhibiting costimulatory CD40 and CD80.

Xiao Y, Deng T, Shang Z, Wang D.

Braz J Med Biol Res. 2017 May 15;50(6):e6227. doi: 10.1590/1414-431X20176227.


A translational approach from an animal model identifies CD80 as a candidate gene for the study of bone phenotypes in postmenopausal women.

Panach L, Serna E, Tarín JJ, Cano A, García-Pérez MÁ.

Osteoporos Int. 2017 May 2. doi: 10.1007/s00198-017-4061-9. [Epub ahead of print]


Tumor regression is mediated via the induction of HER263-71- specific CD8+ CTL activity in a 4T1.2/HER2 tumor model: no involvement of CD80 in tumor control.

Nilofar Danishmalik S, Lee SH, Sin JI.

Oncotarget. 2017 Apr 18;8(16):26771-26788. doi: 10.18632/oncotarget.15816.


PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells.

Ni X, Song Q, Cassady K, Deng R, Jin H, Zhang M, Dong H, Forman S, Martin PJ, Chen YZ, Wang J, Zeng D.

J Clin Invest. 2017 May 1;127(5):1960-1977. doi: 10.1172/JCI91138. Epub 2017 Apr 17.


Recombinant adenovirus of SEA and CD80 genes driven by MMRE and mouse TERT promoter induce effective antitumor immune responses against different types of tumor cells in vitro and in vivo.

Si SY, Liu JL, Liu JL, Xu BX, Li JZ, Qin YY, Song SJ.

Oncol Rep. 2017 May;37(5):3037-3045. doi: 10.3892/or.2017.5563. Epub 2017 Apr 6.


Prediction of Radix Astragali Immunomodulatory Effect of CD80 Expression from Chromatograms by Quantitative Pattern-Activity Relationship.

Ng MC, Lau TY, Fan K, Xu QS, Poon J, Poon SK, Lam MK, Chau FT, Sze DM.

Biomed Res Int. 2017;2017:3923865. doi: 10.1155/2017/3923865. Epub 2017 Feb 28.


Multiscale Modeling of Complex Formation and CD80 Depletion during Immune Synapse Development.

Sugár IP, Das J, Jayaprakash C, Sealfon SC.

Biophys J. 2017 Mar 14;112(5):997-1009. doi: 10.1016/j.bpj.2016.12.052.


Toll-like receptor 3 (TLR-3), TLR-4 and CD80 expression in peripheral blood mononuclear cells and urinary CD80 levels in children with idiopathic nephrotic syndrome.

Mishra OP, Kumar R, Narayan G, Srivastava P, Abhinay A, Prasad R, Singh A, Batra VV.

Pediatr Nephrol. 2017 Aug;32(8):1355-1361. doi: 10.1007/s00467-017-3613-8. Epub 2017 Feb 16.


Direct suppression of autoaggressive CD8+ T cells with CD80/86 blockade in CD8+ T cell-mediated polymyositis models of mice.

Hasegawa H, Kawahata K, Mizoguchi F, Okiyama N, Miyasaka N, Kohsaka H.

Clin Exp Rheumatol. 2017 Jan 27. [Epub ahead of print]


The induction of CD80 and apoptosis on B cells and CD40L in CD4+ T cells in response to seasonal influenza vaccination distinguishes responders versus non-responders in healthy controls and aviremic ART-treated HIV-infected individuals.

Powell AM, Luo Z, Martin L, Wan Z, Ma L, Liao G, Song Y, Li X, Michael Kilby J, Huang L, Jiang W.

Vaccine. 2017 Feb 1;35(5):831-841. doi: 10.1016/j.vaccine.2016.12.026. Epub 2016 Dec 22.


A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.

Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, Zhuang L, Hudak S, Rees DG, Goldberg D, Barton C, Chang L, Vainshtein I, Liang M, Iciek L, Ambery P, Peakman M, Vaughan TJ, Tree TI, Sansom DM, Bowen MA, Minter RR, Jermutus L.

J Immunol. 2017 Jan 1;198(1):528-537. Epub 2016 Nov 23.


Autoantibodies against CD80 in patients with COPD.

Luo XM, Liu XY, Tang JH, Yang W, Ni ZH, Chen QG, Wang X.

Clin Transl Immunology. 2016 Oct 7;5(10):e103. eCollection 2016 Oct.


Expression of co-stimulatory molecules CD80 and CD86 is altered in CD14 + HLA-DR + monocytes from patients with Chagas disease following induction by Trypanosoma cruzi recombinant antigens.

Soares AK, Neves PA, Cavalcanti MD, Marinho SM, Oliveira W Júnior, Souza JR, Lorena VM, Gomes YM.

Rev Soc Bras Med Trop. 2016 Sep-Oct;49(5):632-636. doi: 10.1590/0037-8682-0149-2016.


Increased urinary CD80 excretion and podocyturia in Fabry disease.

Trimarchi H, Canzonieri R, Schiel A, Costales-Collaguazo C, Politei J, Stern A, Paulero M, Rengel T, Andrews J, Forrester M, Lombi M, Pomeranz V, Iriarte R, Muryan A, Zotta E, Sanchez-Niño MD, Ortiz A.

J Transl Med. 2016 Oct 13;14(1):289.


T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts.

Feucht J, Kayser S, Gorodezki D, Hamieh M, Döring M, Blaeschke F, Schlegel P, Bösmüller H, Quintanilla-Fend L, Ebinger M, Lang P, Handgretinger R, Feuchtinger T.

Oncotarget. 2016 Nov 22;7(47):76902-76919. doi: 10.18632/oncotarget.12357.


Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells.

Beyranvand Nejad E, van der Sluis TC, van Duikeren S, Yagita H, Janssen GM, van Veelen PA, Melief CJ, van der Burg SH, Arens R.

Cancer Res. 2016 Oct 15;76(20):6017-6029. Epub 2016 Aug 28.


CD80 Is Upregulated in a Mouse Model with Shear Stress-Induced Atherosclerosis and Allows for Evaluating CD80-Targeting PET Tracers.

Meletta R, Steier L, Borel N, Mu L, Keller C, Chiotellis A, Russo E, Halin C, Ametamey SM, Schibli R, Krämer SD, Müller Herde A.

Mol Imaging Biol. 2017 Feb;19(1):90-99. doi: 10.1007/s11307-016-0987-0.


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