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[Analysis of IFN-gammaR1 (CD119) and IL-12Rbeta1 (CD212) Deficiency by Flow Cytometry].
Gelmez MY, Köksalan K, Çınar S, Hatipoğlu N, Coşkuner T, Topkarcı Z, Hançerli Törün S, Demirbuğa A, Yücel E, Kıykım A, Çokuğraş HC, Gemici-Karaaslan HB, Kendir-Demirkol Y, Deniz G. Gelmez MY, et al. Mikrobiyol Bul. 2023 Jan;57(1):83-96. doi: 10.5578/mb.20239907. Mikrobiyol Bul. 2023. PMID: 36636848 Free article. Turkish.
Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-β Immunotherapeutics.
Market M, Tennakoon G, Scaffidi M, Cook DP, Angka L, Ng J, Tanese de Souza C, Kennedy MA, Vanderhyden BC, Auer RC. Market M, et al. Int J Mol Sci. 2022 Nov 23;23(23):14608. doi: 10.3390/ijms232314608. Int J Mol Sci. 2022. PMID: 36498937 Free PMC article.
Single-cell RNA sequencing (scRNA-seq) was performed on PBMCs from six patients with colorectal cancer having surgery at baseline/on POD1. Intracellular IFNgamma, activating receptors (CD132, CD212, NKG2D, DNAM-1), and downstream target (STAT5, STAT4, p38 MAPK, S6) phospho …
Single-cell RNA sequencing (scRNA-seq) was performed on PBMCs from six patients with colorectal cancer having surgery at baseline/on POD1. I …
A Method of Assessment of Human Natural Killer Cell Phenotype and Function in Whole Blood.
Market M, Tennakoon G, Ng J, Scaffidi M, de Souza CT, Kennedy MA, Auer RC. Market M, et al. Front Immunol. 2020 May 20;11:963. doi: 10.3389/fimmu.2020.00963. eCollection 2020. Front Immunol. 2020. PMID: 32508837 Free PMC article.
Although we did not investigate an exhaustive list of targets, this approach enabled quantification of representative ECS surface markers including activating (NKG2D and DNAM-1) and inhibitory (NKG2A, PD-1, TIGIT, and TIM-3) receptors, cytokine receptors (CD25, CD122, CD132, and …
Although we did not investigate an exhaustive list of targets, this approach enabled quantification of representative ECS surface markers in …
The Virulence of Different Vaccinia Virus Strains Is Directly Proportional to Their Ability To Downmodulate Specific Cell-Mediated Immune Compartments In Vivo.
de Freitas LFD, Oliveira RP, Miranda MCG, Rocha RP, Barbosa-Stancioli EF, Faria AMC, da Fonseca FG. de Freitas LFD, et al. J Virol. 2019 Mar 5;93(6):e02191-18. doi: 10.1128/JVI.02191-18. Print 2019 Mar 15. J Virol. 2019. PMID: 30567985 Free PMC article.
CD4(+) T cells are not only diminished in WR-infected mice but also less activated, as evaluated by the expression of costimulatory molecules such as CD25, CD212, and CD28 and by the production of cytokines, including tumor necrosis factor alpha (TNF-alpha), gamma interfer …
CD4(+) T cells are not only diminished in WR-infected mice but also less activated, as evaluated by the expression of costimulatory molecule …
Levocetirizine modulates lymphocyte activation in patients with allergic rhinitis.
Mahmoud F, Arifhodzic N, Haines D, Novotney L. Mahmoud F, et al. J Pharmacol Sci. 2008 Oct;108(2):149-56. doi: 10.1254/jphs.08037fp. J Pharmacol Sci. 2008. PMID: 18946193 Free article. Clinical Trial.
Relative to the controls, levocetirizine-treated patients exhibited an expected reduction in early phase allergic symptoms, including sneezing (P<0.001), nasal itching (P<0.01), nasal congestion, and running nose (P<0.001); reduced percentages of eosinophils (P<0.05); …
Relative to the controls, levocetirizine-treated patients exhibited an expected reduction in early phase allergic symptoms, including sneezi …
CD34 defines an osteoprogenitor cell population in mouse bone marrow stromal cells.
Abdallah BM, Al-Shammary A, Skagen P, Abu Dawud R, Adjaye J, Aldahmash A, Kassem M. Abdallah BM, et al. Stem Cell Res. 2015 Nov;15(3):449-458. doi: 10.1016/j.scr.2015.09.005. Epub 2015 Sep 21. Stem Cell Res. 2015. PMID: 26413784 Free article.
Among these, we identified osteoprogenitor-associated CD markers expressed only in mBMSC(Bone): CD34, CD54, CD73, CD132, CD200, CD227 and adipoprogenitor-associated CD markers expressed only in mBMSC(Adipo): CD53, CD80, CD134, CD141 and CD212. FACS analysis confirmed these …
Among these, we identified osteoprogenitor-associated CD markers expressed only in mBMSC(Bone): CD34, CD54, CD73, CD132, CD200, CD227 and ad …
Evidence for increased expression of regulatory cytokine receptors interleukin-12R and interleukin-18R in common variable immunodeficiency.
McQuaid A, Tormey VJ, Trafford B, Webster AD, Bofill M. McQuaid A, et al. Clin Exp Immunol. 2003 Nov;134(2):321-7. doi: 10.1046/j.1365-2249.2003.02271.x. Clin Exp Immunol. 2003. PMID: 14616794 Free PMC article.
Cells from CVID patients showed an increase in the percentages of CD212 [interleukin (IL)-12Rbeta1] cells within the CD4+ CD45RA+ and CD8+ CD45RA+ subsets (24% and 41%, respectively), as compared to CD4+ CD45RA+ and CD8+ CD45RA+ in healthy subjects (6% and 23%, respectivey …
Cells from CVID patients showed an increase in the percentages of CD212 [interleukin (IL)-12Rbeta1] cells within the CD4+ CD45RA+ and …
Potentiation of natural killer (NK) cell activity by methanol extract of cultured cambial meristematic cells of wild ginseng and its mechanism.
Jang AY, Song EJ, Shin SH, Hwang PH, Kim SY, Jin YW, Lee EK, Lim MJ, Oh IS, Ahn JY, Nam SY. Jang AY, et al. Life Sci. 2015 Aug 15;135:138-46. doi: 10.1016/j.lfs.2015.06.018. Epub 2015 Jul 2. Life Sci. 2015. PMID: 26141997
However, we observed no increase in NK cell number and unaltered expression of NK cell-activating (NKG2D) and inhibitory (Ly49, CD94/NKG2A) receptors as well as NK cell activation markers (CD25, CD69, CD119, and CD212) in MEGC-treated group compared to the controls. Instea …
However, we observed no increase in NK cell number and unaltered expression of NK cell-activating (NKG2D) and inhibitory (Ly49, CD94/NKG2A) …