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See also: CCM2 CCM2 scaffold protein in the Gene database

ccm2 in Homo sapiensMus musculusRattus norvegicusAll 267 Gene records

Search results

Items: 1 to 20 of 227

1.

Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.

Shenkar R, Peiper A, Pardo H, Moore T, Lightle R, Girard R, Hobson N, Polster SP, Koskimäki J, Zhang D, Lyne SB, Cao Y, Chaudagar K, Saadat L, Gallione C, Pytel P, Liao JK, Marchuk D, Awad IA.

Stroke. 2019 Mar;50(3):738-744. doi: 10.1161/STROKEAHA.118.024058.

PMID:
30744543
2.

Two Novel CCM2 Heterozygous Mutations Associated with Cerebral Cavernous Malformation in a Chinese Family.

Du Q, Shi Z, Chen H, Zhang Y, Wang J, Zhou H.

J Mol Neurosci. 2019 Mar;67(3):467-471. doi: 10.1007/s12031-018-1254-4. Epub 2019 Jan 30.

PMID:
30701383
3.

Novel KRIT1/CCM1 and MGC4607/CCM2 Gene Variants in Chinese Families With Cerebral Cavernous Malformations.

Wang K, Wu D, Zhang B, Zhao G.

Front Neurol. 2018 Dec 21;9:1128. doi: 10.3389/fneur.2018.01128. eCollection 2018.

4.

Two Novel KRIT1 and CCM2 Mutations in Patients Affected by Cerebral Cavernous Malformations: New Information on CCM2 Penetrance.

Scimone C, Donato L, Katsarou Z, Bostantjopoulou S, D'Angelo R, Sidoti A.

Front Neurol. 2018 Nov 14;9:953. doi: 10.3389/fneur.2018.00953. eCollection 2018.

5.

Emerging Pharmacologic Targets in Cerebral Cavernous Malformation and Potential Strategies to Alter the Natural History of a Difficult Disease: A Review.

Chohan MO, Marchiò S, Morrison LA, Sidman RL, Cavenee WK, Dejana E, Yonas H, Pasqualini R, Arap W.

JAMA Neurol. 2018 Nov 26. doi: 10.1001/jamaneurol.2018.3634. [Epub ahead of print]

PMID:
30476961
6.

Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations.

Choi JP, Wang R, Yang X, Wang X, Wang L, Ting KK, Foley M, Cogger V, Yang Z, Liu F, Han Z, Liu R, Baell J, Zheng X.

Sci Adv. 2018 Nov 7;4(11):eaau0731. doi: 10.1126/sciadv.aau0731. eCollection 2018 Nov.

7.

A novel large deletion in CCM1 gene in a Tunisian family.

Tinsa F, Bel Hadj I, Riant F, Ben Romdhane M, Brini I, Tournier-Lasserve E, Louati H, Abdelhak S, Hamouda S, Boussetta K.

Rev Neurol (Paris). 2019 Mar;175(3):194-197. doi: 10.1016/j.neurol.2018.04.013. Epub 2018 Oct 9.

PMID:
30314744
8.

Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations.

Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, Radetzki S, Vogt I, Hähn K, De Luca C, Cardoso C, Hamad S, Igual Gil C, Roy P, Albiges-Rizo C, Faurobert E, von Kries JP, Campillos M, Tournier-Lasserve E, Derry WB, Abdelilah-Seyfried S.

EMBO Mol Med. 2018 Oct;10(10). pii: e9155. doi: 10.15252/emmm.201809155.

9.

A single-center study on 140 patients with cerebral cavernous malformations: 28 new pathogenic variants and functional characterization of a PDCD10 large deletion.

Nardella G, Visci G, Guarnieri V, Castellana S, Biagini T, Bisceglia L, Palumbo O, Trivisano M, Vaira C, Scerrati M, Debrasi D, D'Angelo V, Carella M, Merla G, Mazza T, Castori M, D'Agruma L, Fusco C.

Hum Mutat. 2018 Dec;39(12):1885-1900. doi: 10.1002/humu.23629. Epub 2018 Sep 24.

PMID:
30161288
10.

The CCM1-CCM2 complex controls complementary functions of ROCK1 and ROCK2 that are required for endothelial integrity.

Lisowska J, Rödel CJ, Manet S, Miroshnikova YA, Boyault C, Planus E, De Mets R, Lee HH, Destaing O, Mertani H, Boulday G, Tournier-Lasserve E, Balland M, Abdelilah-Seyfried S, Albiges-Rizo C, Faurobert E.

J Cell Sci. 2018 Aug 13;131(15). pii: jcs216093. doi: 10.1242/jcs.216093.

11.

Phenotypic characterization of murine models of cerebral cavernous malformations.

Zeineddine HA, Girard R, Saadat L, Shen L, Lightle R, Moore T, Cao Y, Hobson N, Shenkar R, Avner K, Chaudager K, Koskimäki J, Polster SP, Fam MD, Shi C, Lopez-Ramirez MA, Tang AT, Gallione C, Kahn ML, Ginsberg M, Marchuk DA, Awad IA.

Lab Invest. 2019 Mar;99(3):319-330. doi: 10.1038/s41374-018-0030-y. Epub 2018 Jun 26.

12.

A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation.

Thomas C, Zühlsdorf A, Hörtnagel K, Mulahasanovic L, Grauer OM, Kümpers P, Wiendl H, Meuth SG.

Front Neurol. 2018 May 25;9:383. doi: 10.3389/fneur.2018.00383. eCollection 2018.

13.

Mutational analysis of CCM1, CCM2 and CCM3 in a Han Chinese cohort with multiple cerebral cavernous malformations in Taiwan.

Jih KY, Chung CP, Chang YY, Hung PL, Soong BW, Liao YC, Lan MY, Lee YC.

Clin Genet. 2018 Oct;94(3-4):389-390. doi: 10.1111/cge.13377. Epub 2018 May 22. No abstract available.

PMID:
29787619
14.

Cerebral Cavernous Malformations: An Update on Prevalence, Molecular Genetic Analyses, and Genetic Counselling.

Spiegler S, Rath M, Paperlein C, Felbor U.

Mol Syndromol. 2018 Feb;9(2):60-69. doi: 10.1159/000486292. Epub 2018 Jan 25. Review.

15.

Chitin/clay microspheres with hierarchical architecture for highly efficient removal of organic dyes.

Xu R, Mao J, Peng N, Luo X, Chang C.

Carbohydr Polym. 2018 May 15;188:143-150. doi: 10.1016/j.carbpol.2018.01.073. Epub 2018 Jan 31.

PMID:
29525150
16.

Heg1 and Ccm1/2 proteins control endocardial mechanosensitivity during zebrafish valvulogenesis.

Donat S, Lourenço M, Paolini A, Otten C, Renz M, Abdelilah-Seyfried S.

Elife. 2018 Feb 1;7. pii: e28939. doi: 10.7554/eLife.28939.

17.

Human Malformation Syndromes of Defective GLI: Opposite Phenotypes of 2q14.2 (GLI2) and 7p14.2 (GLI3) Microdeletions and a GLIA/R Balance Model.

Niida Y, Inoue M, Ozaki M, Takase E.

Cytogenet Genome Res. 2017;153(2):56-65. doi: 10.1159/000485227. Epub 2018 Jan 4. Erratum in: Cytogenet Genome Res. 2018;154(4):234.

PMID:
29298444
18.

First large genomic inversion in familial cerebral cavernous malformation identified by whole genome sequencing.

Spiegler S, Rath M, Hoffjan S, Dammann P, Sure U, Pagenstecher A, Strom T, Felbor U.

Neurogenetics. 2018 Jan;19(1):55-59. doi: 10.1007/s10048-017-0531-7. Epub 2017 Dec 2.

PMID:
29197946
19.

A novel CCM1/KRIT1 heterozygous deletion mutation (c.1919delT) in a Chinese family with familial cerebral cavernous malformation.

Yang C, Wu B, Zhong H, Li Y, Zheng X, Xu Y.

Clin Neurol Neurosurg. 2018 Jan;164:44-46. doi: 10.1016/j.clineuro.2017.11.005. Epub 2017 Nov 21.

PMID:
29169046
20.

Clinical Management of Cavernous Malformations.

Flemming KD.

Curr Cardiol Rep. 2017 Oct 18;19(12):122. doi: 10.1007/s11886-017-0931-1. Review.

PMID:
29046973

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