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Items: 1 to 20 of 42


Soluble CD83 Alleviates Experimental Autoimmune Uveitis by Inhibiting Filamentous Actin-Dependent Calcium Release in Dendritic Cells.

Lin W, Buscher K, Wang B, Fan Z, Song N, Li P, Yue Y, Li B, Li C, Bi H.

Front Immunol. 2018 Jul 9;9:1567. doi: 10.3389/fimmu.2018.01567. eCollection 2018.


Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.

Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh HQ, Kobiyama K, Hamers AAJ, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Pramod AB, Ghosh AK, Anto Michel N, Hoppe N, Hilgendorf I, Zirlik A, Hedrick CC, Ley K, Wolf D.

Circ Res. 2018 Jun 8;122(12):1675-1688. doi: 10.1161/CIRCRESAHA.117.312513. Epub 2018 Mar 15.


A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.

Wolf D, Anto-Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann JD, Lim B, Bäuml M, Marki A, Mauler M, Duerschmied D, Fan Z, Winkels H, Sidler D, Diehl P, Zajonc DM, Hilgendorf I, Stachon P, Marchini T, Willecke F, Schell M, Sommer B, von Zur Muhlen C, Reinöhl J, Gerhardt T, Plow EF, Yakubenko V, Libby P, Bode C, Ley K, Peter K, Zirlik A.

Nat Commun. 2018 Feb 6;9(1):525. doi: 10.1038/s41467-018-02896-8.


Inflammatory Pathways Regulated by Tumor Necrosis Receptor-Associated Factor 1 Protect From Metabolic Consequences in Diet-Induced Obesity.

Anto Michel N, Colberg C, Buscher K, Sommer B, Pramod AB, Ehinger E, Dufner B, Hoppe N, Pfeiffer K, Marchini T, Willecke F, Stachon P, Hilgendorf I, Heidt T, von Zur Muhlen C, von Elverfeldt D, Pfeifer D, Schüle R, Kintscher U, Brachs S, Ley K, Bode C, Zirlik A, Wolf D.

Circ Res. 2018 Mar 2;122(5):693-700. doi: 10.1161/CIRCRESAHA.117.312055. Epub 2018 Jan 22.


Patrolling Mechanics of Non-Classical Monocytes in Vascular Inflammation.

Buscher K, Marcovecchio P, Hedrick CC, Ley K.

Front Cardiovasc Med. 2017 Dec 19;4:80. doi: 10.3389/fcvm.2017.00080. eCollection 2017. Review.


The TWEAK/Fn14 pathway is required for calcineurin inhibitor toxicity of the kidneys.

Claus M, Herro R, Wolf D, Buscher K, Rudloff S, Huynh-Do U, Burkly L, Croft M, Sidler D.

Am J Transplant. 2018 Jul;18(7):1636-1645. doi: 10.1111/ajt.14632. Epub 2018 Feb 6.


Rolling neutrophils form tethers and slings under physiologic conditions in vivo.

Marki A, Buscher K, Mikulski Z, Pries A, Ley K.

J Leukoc Biol. 2018 Jan;103(1):67-70. doi: 10.1189/jlb.1AB0617-230R. Epub 2017 Dec 28.


Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival.

Buscher K, Ehinger E, Gupta P, Pramod AB, Wolf D, Tweet G, Pan C, Mills CD, Lusis AJ, Ley K.

Nat Commun. 2017 Jul 24;8:16041. doi: 10.1038/ncomms16041.


Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis.

Quintar A, McArdle S, Wolf D, Marki A, Ehinger E, Vassallo M, Miller J, Mikulski Z, Ley K, Buscher K.

Circ Res. 2017 May 26;120(11):1789-1799. doi: 10.1161/CIRCRESAHA.117.310739. Epub 2017 Mar 16.


Endothelial Basement Membrane Laminin 511 Contributes to Endothelial Junctional Tightness and Thereby Inhibits Leukocyte Transmigration.

Song J, Zhang X, Buscher K, Wang Y, Wang H, Di Russo J, Li L, Lütke-Enking S, Zarbock A, Stadtmann A, Striewski P, Wirth B, Kuzmanov I, Wiendl H, Schulte D, Vestweber D, Sorokin L.

Cell Rep. 2017 Jan 31;18(5):1256-1269. doi: 10.1016/j.celrep.2016.12.092.


Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules.

Buscher K, Wang H, Zhang X, Striewski P, Wirth B, Saggu G, Lütke-Enking S, Mayadas TN, Ley K, Sorokin L, Song J.

Nat Commun. 2016 Mar 4;7:10828. doi: 10.1038/ncomms10828.


The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury.

Rübig E, Stypmann J, Van Slyke P, Dumont DJ, Spieker T, Buscher K, Reuter S, Goerge T, Pavenstädt H, Kümpers P.

Sci Rep. 2016 Feb 25;6:22111. doi: 10.1038/srep22111.


Structural requirements of mono- and multivalent L-selectin blocking aptamers for enhanced receptor inhibition in vitro and in vivo.

Riese SB, Buscher K, Enders S, Kuehne C, Tauber R, Dernedde J.

Nanomedicine. 2016 May;12(4):901-908. doi: 10.1016/j.nano.2015.12.379. Epub 2016 Jan 7.


Prevalence of elevated ALT values, HBsAg, and anti-HCV in the primary care setting and evaluation of guideline defined hepatitis risk scenarios.

Wolffram I, Petroff D, Bätz O, Jedrysiak K, Kramer J, Tenckhoff H, Berg T, Wiegand J; German Check-Up 35+ Study Group.

J Hepatol. 2015 Jun;62(6):1256-64. doi: 10.1016/j.jhep.2015.01.011. Epub 2015 Jan 21.


Breast pain in a patient on dialysis: a rare manifestation of calcific uraemic arteriolopathy.

Buscher K, Gabriëls G, Barth P, Pavenstädt H.

BMJ Case Rep. 2015 Jan 9;2015. pii: bcr2014207946. doi: 10.1136/bcr-2014-207946.


Heterotropic modulation of selectin affinity by allosteric antibodies affects leukocyte rolling.

Riese SB, Kuehne C, Tedder TF, Hallmann R, Hohenester E, Buscher K.

J Immunol. 2014 Feb 15;192(4):1862-9. doi: 10.4049/jimmunol.1302147. Epub 2014 Jan 15.


The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow.

Stadtmann A, Germena G, Block H, Boras M, Rossaint J, Sundd P, Lefort C, Fisher CI, Buscher K, Gelschefarth B, Urzainqui A, Gerke V, Ley K, Zarbock A.

J Exp Med. 2013 Oct 21;210(11):2171-80. doi: 10.1084/jem.20130664. Epub 2013 Oct 14.


L-selectin--a dynamic regulator of leukocyte migration.

Wedepohl S, Beceren-Braun F, Riese S, Buscher K, Enders S, Bernhard G, Kilian K, Blanchard V, Dernedde J, Tauber R.

Eur J Cell Biol. 2012 Apr;91(4):257-64. doi: 10.1016/j.ejcb.2011.02.007. Epub 2011 May 4. Review.


Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI.

Büscher K, Judenhofer MS, Kuhlmann MT, Hermann S, Wehrl HF, Schäfers KP, Schäfers M, Pichler BJ, Stegger L.

J Nucl Med. 2010 Aug;51(8):1277-84. doi: 10.2967/jnumed.110.076448. Epub 2010 Jul 21.


The transmembrane domains of L-selectin and CD44 regulate receptor cell surface positioning and leukocyte adhesion under flow.

Buscher K, Riese SB, Shakibaei M, Reich C, Dernedde J, Tauber R, Ley K.

J Biol Chem. 2010 Apr 30;285(18):13490-7. doi: 10.1074/jbc.M110.102640. Epub 2010 Mar 8.

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