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See 1 citation in Bull Exp Biol Med 2015:

Bull Exp Biol Med. 2015 Dec;160(2):278-80. doi: 10.1007/s10517-015-3149-5. Epub 2015 Dec 8.

Lipid Status and Predisposing Genes in Patients with Diabetes Mellitus Type 1 from Various Ethnic Groups.

Author information

1
Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
2
Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia. mops_my@front.ru.

Abstract

The peculiarities of HLA class II profile and lipid metabolism were examined in Buryat and Russian ethnic groups of patients with diabetes mellitus type 1. The incidence of type 1 haplotypes in HLA class II gene family was lower in Buryats than that in Russians. In comparison with Russians, the course of diabetes mellitus type 1 in Buryat patients was characterized with a lower content of total lipids, triacylglycerols, total cholesterol, and LDL, which probably explains a more favorable course of the disease in Buryat population.

KEYWORDS:

diabetes mellitus type 1; ethnos; lipid metabolism; predisposing genes

PMID:
26642791
DOI:
10.1007/s10517-015-3149-5
[Indexed for MEDLINE]

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