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See 1 citation in Bull Exp Biol Med 2015:

Bull Exp Biol Med. 2015 Feb;158(4):528-31. doi: 10.1007/s10517-015-2801-4. Epub 2015 Feb 24.

Endogenous progenitors as the source of cell material for ischemic damage repair in experimental myocardial infarction under conditions of changed concentration of vascular endothelial growth factor.

Author information

1
Research Center of Reconstructive and Restorative Surgery, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia, shurygin@rambler.ru.

Abstract

We studied the effect of VEGF-A in experimental myocardial infarction on attraction of progenitor cells into the regeneration zone. The appearance of CD34(+)CD45(+) cells known as low-differentiated progenitor cells was observed in the damaged myocardial tissue in the presence of a considerable excess of VEGF-A. These cells can act as precursors of mesenchymal tissues depending on the direction of differentiation.

PMID:
25708340
DOI:
10.1007/s10517-015-2801-4
[Indexed for MEDLINE]

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