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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 2
1998 1
2005 2
2006 2
2007 2
2008 3
2009 1
2010 1
2014 1
2017 1
2024 1

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16 results

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Page 1
Medicinal chemistry of Hsp90 inhibitors.
Drysdale MJ, Brough PA. Drysdale MJ, et al. Among authors: brough pa. Curr Top Med Chem. 2008;8(10):859-68. doi: 10.2174/156802608784911644. Curr Top Med Chem. 2008. PMID: 18673171 Review.
Lindane neurotoxicity.
Boffa MJ, Brough PA, Ead RD. Boffa MJ, et al. Among authors: brough pa. Br J Dermatol. 1995 Dec;133(6):1013. doi: 10.1111/j.1365-2133.1995.tb06950.x. Br J Dermatol. 1995. PMID: 8547026 No abstract available.
Discovery and development of pyrazole-scaffold Hsp90 inhibitors.
McDonald E, Jones K, Brough PA, Drysdale MJ, Workman P. McDonald E, et al. Among authors: brough pa. Curr Top Med Chem. 2006;6(11):1193-203. doi: 10.2174/156802606777812086. Curr Top Med Chem. 2006. PMID: 16842156 Review.
Ligand-Based Competition Binding by Real-Time 19F NMR in Human Cells.
Luchinat E, Barbieri L, Davis B, Brough PA, Pennestri M, Banci L. Luchinat E, et al. Among authors: brough pa. J Med Chem. 2024 Jan 25;67(2):1115-1126. doi: 10.1021/acs.jmedchem.3c01600. Epub 2024 Jan 12. J Med Chem. 2024. PMID: 38215028 Free PMC article.
Targeting Hsp90 for the treatment of cancer.
Drysdale MJ, Brough PA, Massey A, Jensen MR, Schoepfer J. Drysdale MJ, et al. Among authors: brough pa. Curr Opin Drug Discov Devel. 2006 Jul;9(4):483-95. Curr Opin Drug Discov Devel. 2006. PMID: 16889231 Review.
Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase.
Brough PA, Baker L, Bedford S, Brown K, Chavda S, Chell V, D'Alessandro J, Davies NG, Davis B, Le Strat L, Macias AT, Maddox D, Mahon PC, Massey AJ, Matassova N, McKenna S, Meissner JW, Moore JD, Murray JB, Northfield CJ, Parry C, Parsons R, Roughley SD, Shaw T, Simmonite H, Stokes S, Surgenor A, Stefaniak E, Robertson A, Wang Y, Webb P, Whitehead N, Wood M. Brough PA, et al. J Med Chem. 2017 Mar 23;60(6):2271-2286. doi: 10.1021/acs.jmedchem.6b01478. Epub 2017 Feb 15. J Med Chem. 2017. PMID: 28199108
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer.
Brough PA, Aherne W, Barril X, Borgognoni J, Boxall K, Cansfield JE, Cheung KM, Collins I, Davies NG, Drysdale MJ, Dymock B, Eccles SA, Finch H, Fink A, Hayes A, Howes R, Hubbard RE, James K, Jordan AM, Lockie A, Martins V, Massey A, Matthews TP, McDonald E, Northfield CJ, Pearl LH, Prodromou C, Ray S, Raynaud FI, Roughley SD, Sharp SY, Surgenor A, Walmsley DL, Webb P, Wood M, Workman P, Wright L. Brough PA, et al. J Med Chem. 2008 Jan 24;51(2):196-218. doi: 10.1021/jm701018h. Epub 2007 Nov 20. J Med Chem. 2008. PMID: 18020435
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone.
Brough PA, Barril X, Borgognoni J, Chene P, Davies NG, Davis B, Drysdale MJ, Dymock B, Eccles SA, Garcia-Echeverria C, Fromont C, Hayes A, Hubbard RE, Jordan AM, Jensen MR, Massey A, Merrett A, Padfield A, Parsons R, Radimerski T, Raynaud FI, Robertson A, Roughley SD, Schoepfer J, Simmonite H, Sharp SY, Surgenor A, Valenti M, Walls S, Webb P, Wood M, Workman P, Wright L. Brough PA, et al. J Med Chem. 2009 Aug 13;52(15):4794-809. doi: 10.1021/jm900357y. J Med Chem. 2009. PMID: 19610616
16 results