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Application of Deacetylated Poly-N-Acetyl Glucosamine Nanoparticles for the Delivery of miR-126 for the Treatment of Cecal Ligation and Puncture-Induced Sepsis.

Jones Buie JN, Zhou Y, Goodwin AJ, Cook JA, Vournakis J, Demcheva M, Broome AM, Dixit S, Halushka PV, Fan H.

Inflammation. 2018 Sep 23. doi: 10.1007/s10753-018-0882-8. [Epub ahead of print]


Organ preservation with targeted rapamycin nanoparticles: a pre-treatment strategy preventing chronic rejection in vivo.

Zhu P, Atkinson C, Dixit S, Cheng Q, Tran D, Patel K, Jiang YL, Esckilsen S, Miller K, Bazzle G, Allen P, Moore A, Broome AM, Nadig SN.

RSC Adv. 2018 Jul 23;8(46):25909-25919. doi: 10.1039/c8ra01555d.



Broome AM.

Adv Cancer Res. 2018;139:xiii-xiv. doi: 10.1016/S0065-230X(18)30054-X. No abstract available.


Gold Nanoparticles for the Delivery of Cancer Therapeutics.

Connor DM, Broome AM.

Adv Cancer Res. 2018;139:163-184. doi: 10.1016/bs.acr.2018.05.001. Epub 2018 May 24.


Localized delivery of therapeutic doxorubicin dose across the canine blood-brain barrier with hyperthermia and temperature sensitive liposomes.

Bredlau AL, Motamarry A, Chen C, McCrackin MA, Helke K, Armeson KE, Bynum K, Broome AM, Haemmerich D.

Drug Deliv. 2018 Nov;25(1):973-984. doi: 10.1080/10717544.2018.1461280.


Biotinylated Bioluminescent Probe for Long Lasting Targeted in Vivo Imaging of Xenografted Brain Tumors in Mice.

Jiang YL, Zhu Y, Moore AB, Miller K, Broome AM.

ACS Chem Neurosci. 2018 Jan 17;9(1):100-106. doi: 10.1021/acschemneuro.7b00111. Epub 2017 Jun 5.


Fluorescence and Bioluminescence Imaging of Orthotopic Brain Tumors in Mice.

McKinnon E, Moore A, Dixit S, Zhu Y, Broome AM.

Methods Mol Biol. 2017;1530:283-305. doi: 10.1007/978-1-4939-6646-2_17.


Delivery of a drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers.

Miller K, Dixit S, Bredlau AL, Moore A, McKinnon E, Broome AM.

Nanomedicine (Lond). 2016 Mar;11(6):581-95. doi: 10.2217/nnm.15.218. Epub 2016 Mar 22.


Nanotechnology Applications for Diffuse Intrinsic Pontine Glioma.

Bredlau AL, Dixit S, Chen C, Broome AM.

Curr Neuropharmacol. 2017;15(1):104-115. Review.


Thermal Therapy Approaches for Treatment of Brain Tumors in Animals and Humans.

Bredlau AL, McCrackin MA, Motamarry A, Helke K, Chen C, Broome AM, Haemmerich D.

Crit Rev Biomed Eng. 2016;44(6):443-457. doi: 10.1615/CritRevBiomedEng.2017021249.


Mutations in DCHS1 cause mitral valve prolapse.

Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA.

Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10.


Dual Receptor-Targeted Theranostic Nanoparticles for Localized Delivery and Activation of Photodynamic Therapy Drug in Glioblastomas.

Dixit S, Miller K, Zhu Y, McKinnon E, Novak T, Kenney ME, Broome AM.

Mol Pharm. 2015 Sep 8;12(9):3250-60. doi: 10.1021/acs.molpharmaceut.5b00216. Epub 2015 Aug 24.


Immunosuppressive nano-therapeutic micelles downregulate endothelial cell inflammation and immunogenicity.

Nadig SN, Dixit SK, Levey N, Esckilsen S, Miller K, Dennis W, Atkinson C, Broome AM.

RSC Adv. 2015;5(54):43552-43562. doi: 10.1039/C5RA04057D. Epub 2015 Apr 24.


Peptide-Targeted Gold Nanoparticles for Photodynamic Therapy of Brain Cancer.

Meyers JD, Cheng Y, Broome AM, Agnes RS, Schluchter MD, Margevicius S, Wang X, Kenney ME, Burda C, Basilion JP.

Part Part Syst Charact. 2015 Apr;32(4):448-457.


Optical imaging of targeted β-galactosidase in brain tumors to detect EGFR levels.

Broome AM, Ramamurthy G, Lavik K, Liggett A, Kinstlinger I, Basilion J.

Bioconjug Chem. 2015 Apr 15;26(4):660-8. doi: 10.1021/bc500597y. Epub 2015 Mar 30.


Transferrin receptor-targeted theranostic gold nanoparticles for photosensitizer delivery in brain tumors.

Dixit S, Novak T, Miller K, Zhu Y, Kenney ME, Broome AM.

Nanoscale. 2015 Feb 7;7(5):1782-90. doi: 10.1039/c4nr04853a.


Nanobubble ultrasound contrast agents for enhanced delivery of thermal sensitizer to tumors undergoing radiofrequency ablation.

Perera RH, Solorio L, Wu H, Gangolli M, Silverman E, Hernandez C, Peiris PM, Broome AM, Exner AA.

Pharm Res. 2014 Jun;31(6):1407-17. doi: 10.1007/s11095-013-1100-x. Epub 2013 Aug 14. Erratum in: Pharm Res. 2014 Jul;31(7):1877.


Biodistribution and clearance of a filamentous plant virus in healthy and tumor-bearing mice.

Shukla S, Wen AM, Ayat NR, Commandeur U, Gopalkrishnan R, Broome AM, Lozada KW, Keri RA, Steinmetz NF.

Nanomedicine (Lond). 2014 Feb;9(2):221-35. doi: 10.2217/nnm.13.75. Epub 2013 Jul 9.


An optical probe for noninvasive molecular imaging of orthotopic brain tumors overexpressing epidermal growth factor receptor.

Agnes RS, Broome AM, Wang J, Verma A, Lavik K, Basilion JP.

Mol Cancer Ther. 2012 Oct;11(10):2202-11. doi: 10.1158/1535-7163.MCT-12-0211. Epub 2012 Jul 17.


Role of Pluronic block copolymers in modulation of heat shock protein 70 expression.

Perera RH, Krupka TM, Wu H, Traughber B, Dremann D, Broome AM, Exner AA.

Int J Hyperthermia. 2011;27(7):672-81. doi: 10.3109/02656736.2011.608218.

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