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Human neurons from Christianson syndrome iPSCs reveal mutation-specific responses to rescue strategies.
Lizarraga SB, Ma L, Maguire AM, van Dyck LI, Wu Q, Ouyang Q, Kavanaugh BC, Nagda D, Livi LL, Pescosolido MF, Schmidt M, Alabi S, Cowen MH, Brito-Vargas P, Hoffman-Kim D, Gamsiz Uzun ED, Schlessinger A, Jones RN, Morrow EM. Lizarraga SB, et al. Among authors: brito vargas p. Sci Transl Med. 2021 Feb 10;13(580):eaaw0682. doi: 10.1126/scitranslmed.aaw0682. Sci Transl Med. 2021. PMID: 33568516 Free PMC article.
Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition.
Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Willis DE, Havton LA, Schiavo G, Giger RJ, Langley B, Twiss JL. Kalinski AL, et al. Among authors: brito vargas p. J Cell Biol. 2019 Jun 3;218(6):1871-1890. doi: 10.1083/jcb.201702187. Epub 2019 May 8. J Cell Biol. 2019. PMID: 31068376 Free PMC article.
The anabolic steroids testosterone propionate and nandrolone, but not 17alpha-methyltestosterone, induce conditioned place preference in adult mice.
Parrilla-Carrero J, Figueroa O, Lugo A, García-Sosa R, Brito-Vargas P, Cruz B, Rivera M, Barreto-Estrada JL. Parrilla-Carrero J, et al. Among authors: brito vargas p. Drug Alcohol Depend. 2009 Feb 1;100(1-2):122-7. doi: 10.1016/j.drugalcdep.2008.09.014. Epub 2008 Nov 22. Drug Alcohol Depend. 2009. PMID: 19028026 Free PMC article.