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Isolation of Retinal Arterioles for Ex Vivo Cell Physiology Studies.

Curtis TM, McLaughlin D, O'Hare M, Kur J, Barabas P, Revolta G, Scholfield CN, McGeown JG, McGahon MK.

J Vis Exp. 2018 Jul 14;(137). doi: 10.3791/57944.


Cellular rearrangement of the prechordal plate contributes to eye degeneration in the cavefish.

Ren X, Hamilton N, Müller F, Yamamoto Y.

Dev Biol. 2018 Sep 15;441(2):221-234. doi: 10.1016/j.ydbio.2018.07.017. Epub 2018 Jul 19.


Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure.

Baliga RS, Preedy MEJ, Dukinfield MS, Chu SM, Aubdool AA, Bubb KJ, Moyes AJ, Tones MA, Hobbs AJ.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7428-E7437. doi: 10.1073/pnas.1800996115. Epub 2018 Jul 16.


Assessment of Kidney Function in Mouse Models of Glomerular Disease.

Stevens M, Oltean S.

J Vis Exp. 2018 Jun 30;(136). doi: 10.3791/57764.


Solute movement in the t-tubule system of rabbit and mouse cardiomyocytes.

Kong CHT, Rog-Zielinska EA, Kohl P, Orchard CH, Cannell MB.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7073-E7080. doi: 10.1073/pnas.1805979115. Epub 2018 Jul 10.


Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay.

Brash JT, Ruhrberg C, Fantin A.

J Vis Exp. 2018 Jun 19;(136). doi: 10.3791/57524.


Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation.

Gage MC, Bécares N, Louie R, Waddington KE, Zhang Y, Tittanegro TH, Rodríguez-Lorenzo S, Jathanna A, Pourcet B, Pello OM, De la Rosa JV, Castrillo A, Pineda-Torra I.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6556-E6565. doi: 10.1073/pnas.1721245115. Epub 2018 Jun 27.


Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane.

Burdyga A, Surdo NC, Monterisi S, Di Benedetto G, Grisan F, Penna E, Pellegrini L, Zaccolo M, Bortolozzi M, Swietach P, Pozzan T, Lefkimmiatis K.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6497-E6506. doi: 10.1073/pnas.1806318115. Epub 2018 Jun 25. Erratum in: Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7882.


The developmental origin of heart size and shape differences in Astyanax mexicanus populations.

Tang JLY, Guo Y, Stockdale WT, Rana K, Killen AC, Mommersteeg MTM, Yamamoto Y.

Dev Biol. 2018 Sep 15;441(2):272-284. doi: 10.1016/j.ydbio.2018.06.009. Epub 2018 Jun 22.


Expanding the horizons of microRNA bioinformatics.

Huntley RP, Kramarz B, Sawford T, Umrao Z, Kalea A, Acquaah V, Martin MJ, Mayr M, Lovering RC.

RNA. 2018 Aug;24(8):1005-1017. doi: 10.1261/rna.065565.118. Epub 2018 Jun 5.


FTI-277 inhibits smooth muscle cell calcification by up-regulating PI3K/Akt signaling and inhibiting apoptosis.

Ponnusamy A, Sinha S, Hyde GD, Borland SJ, Taylor RF, Pond E, Eyre HJ, Inkson CA, Gilmore A, Ashton N, Kalra PA, Canfield AE.

PLoS One. 2018 Apr 24;13(4):e0196232. doi: 10.1371/journal.pone.0196232. eCollection 2018.


Role of the novel endoribonuclease SLFN14 and its disease-causing mutations in ribosomal degradation.

Fletcher SJ, Pisareva VP, Khan AO, Tcherepanov A, Morgan NV, Pisarev AV.

RNA. 2018 Jul;24(7):939-949. doi: 10.1261/rna.066415.118. Epub 2018 Apr 20.


Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations.

Cartier J, Smith T, Thomson JP, Rose CM, Khulan B, Heger A, Meehan RR, Drake AJ.

Genome Biol. 2018 Apr 10;19(1):50. doi: 10.1186/s13059-018-1422-4.


Cardiac Dysfunction and Metabolic Inflexibility in a Mouse Model of Diabetes Without Dyslipidemia.

Rohm M, Savic D, Ball V, Curtis MK, Bonham S, Fischer R, Legrave N, MacRae JI, Tyler DJ, Ashcroft FM.

Diabetes. 2018 Jun;67(6):1057-1067. doi: 10.2337/db17-1195. Epub 2018 Apr 2.


Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping.

Costa FC, Francisco AF, Jayawardhana S, Calderano SG, Lewis MD, Olmo F, Beneke T, Gluenz E, Sunter J, Dean S, Kelly JM, Taylor MC.

PLoS Negl Trop Dis. 2018 Apr 2;12(4):e0006388. doi: 10.1371/journal.pntd.0006388. eCollection 2018 Apr.


Reversible Covalent Reaction of Levosimendan with Cardiac Troponin C in Vitro and in Situ.

Klein BA, Reiz B, Robertson IM, Irving M, Li L, Sun YB, Sykes BD.

Biochemistry. 2018 Apr 17;57(15):2256-2265. doi: 10.1021/acs.biochem.8b00109. Epub 2018 Mar 30.


Cardiac electrophysiological adaptations in the equine athlete-Restitution analysis of electrocardiographic features.

Li M, Chadda KR, Matthews GDK, Marr CM, Huang CL, Jeevaratnam K.

PLoS One. 2018 Mar 9;13(3):e0194008. doi: 10.1371/journal.pone.0194008. eCollection 2018.


A Novel Mechanism for Calmodulin-Dependent Inactivation of Transient Receptor Potential Vanilloid 6.

Bate N, Caves RE, Skinner SP, Goult BT, Basran J, Mitcheson JS, Vuister GW.

Biochemistry. 2018 May 8;57(18):2611-2622. doi: 10.1021/acs.biochem.7b01286. Epub 2018 Apr 13.


Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?

Senis YA, Barr AJ.

Molecules. 2018 Mar 2;23(3). pii: E569. doi: 10.3390/molecules23030569. Review.


Role of the Aryl Hydrocarbon Receptor in Su5416/Hypoxia-induced Pulmonary Hypertension: A New Mechanism for an "Old" Model.

Strielkov I, Weissmann N.

Am J Respir Cell Mol Biol. 2018 Mar;58(3):279-281. doi: 10.1165/rcmb.2017-0359ED. No abstract available.


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