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Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).

Welte T, Dellinger RP, Ebelt H, Ferrer M, Opal SM, Singer M, Vincent JL, Werdan K, Martin-Loeches I, Almirall J, Artigas A, Ignacio Ayestarán J, Nuding S, Ferrer R, Sirgo Rodríguez G, Shankar-Hari M, Álvarez-Lerma F, Riessen R, Sirvent JM, Kluge S, Zacharowski K, Bonastre Mora J, Lapp H, Wöbker G, Achtzehn U, Brealey D, Kempa A, Sánchez García M, Brederlau J, Kochanek M, Reschreiter HP, Wise MP, Belohradsky BH, Bobenhausen I, Dälken B, Dubovy P, Langohr P, Mayer M, Schüttrumpf J, Wartenberg-Demand A, Wippermann U, Wolf D, Torres A.

Intensive Care Med. 2018 Apr;44(4):438-448. doi: 10.1007/s00134-018-5143-7. Epub 2018 Apr 9.


The effect of a novel extracorporeal cytokine hemoadsorption device on IL-6 elimination in septic patients: A randomized controlled trial.

Schädler D, Pausch C, Heise D, Meier-Hellmann A, Brederlau J, Weiler N, Marx G, Putensen C, Spies C, Jörres A, Quintel M, Engel C, Kellum JA, Kuhlmann MK.

PLoS One. 2017 Oct 30;12(10):e0187015. doi: 10.1371/journal.pone.0187015. eCollection 2017.


[Erratum to: Dexmedetomidine in the treatment of acute alcohol withdrawal delirium].

Gerresheim G, Brederlau J, Schwemmer U.

Anaesthesist. 2016 Sep;65(9):712. German. No abstract available.


[Dexmedetomidine in the treatment of acute alcohol withdrawal delirium].

Gerresheim G, Brederlau J, Schwemmer U.

Anaesthesist. 2016 Jul;65(7):525-31. doi: 10.1007/s00101-016-0190-3. German. Erratum in: Anaesthesist. 2016 Sep;65(9):712.


Patients with severe ARDS already positioned prone: why don't we leave them in the prone position during transport and CT scan?

Brederlau J, Wurmb T, Schwemmer U.

Minerva Anestesiol. 2016 Jun;82(6):720-1. Epub 2015 Dec 1. No abstract available.


[Patients' declared intentions and emergency medicine].

Wurmb T, Brederlau J.

Med Klin Intensivmed Notfmed. 2016 Mar;111(2):113-7. doi: 10.1007/s00063-015-0086-z. Epub 2015 Sep 15. Review. German.


Routine follow-up cranial computed tomography for deeply sedated, intubated, and ventilated multiple trauma patients with suspected severe head injury.

Wurmb TE, Schlereth S, Kredel M, Muellenbach RM, Wunder C, Brederlau J, Roewer N, Kenn W, Kunze E.

Biomed Res Int. 2014;2014:361949. doi: 10.1155/2014/361949. Epub 2014 Jan 20.


Influence of apneic oxygenation and minimal tidal volumes on ventilator-associated lung injury.

Johannes A, Kredel M, Zollhoefer B, Schlegel N, Von Kirschbaum C, Brederlau J, Kranke P, Roewer N, Muellenbach RM.

Minerva Anestesiol. 2014 May;80(5):526-36. Epub 2013 Nov 13.


Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus 'conventional' protective ventilation (6 ml/kg) in severe ARDS: the prospective randomized Xtravent-study.

Bein T, Weber-Carstens S, Goldmann A, Müller T, Staudinger T, Brederlau J, Muellenbach R, Dembinski R, Graf BM, Wewalka M, Philipp A, Wernecke KD, Lubnow M, Slutsky AS.

Intensive Care Med. 2013 May;39(5):847-56. doi: 10.1007/s00134-012-2787-6. Epub 2013 Jan 10.


[If the extracorporeal lung assist comes to its limit: use and management of extracorporeal membrane oxygenation in severe acute respiratory distress syndrome].

Küstermann J, Brederlau J, Kranke P, Roewer N, Muellenbach RM.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2012 Oct;47(10):646-54. doi: 10.1055/s-0032-1329402. Epub 2012 Oct 24. Review. German.


[If mechanical ventilation comes to its limits: extracorporeal lung assist].

Brederlau J, Küstermann J, Kredel M, Roewer N, Muellenbach RM.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2012 Oct;47(10):636-44. doi: 10.1055/s-0032-1329401. Epub 2012 Oct 24. German.


Extracorporeal lung assist might avoid invasive ventilation in exacerbation of COPD.

Brederlau J, Wurmb T, Wilczek S, Will K, Maier S, Kredel M, Roewer N, Muellenbach RM.

Eur Respir J. 2012 Sep;40(3):783-5. doi: 10.1183/09031936.00006012. No abstract available.


[The DGAI training module 2 in anaesthetic focussed sonography: vascular sonography].

Trautner H, Markus CK, Steinhübel B, Schwemmer U, Greim CA, Brederlau J.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2011 Nov;46(11-12):756-9. doi: 10.1055/s-0031-1297184. Epub 2011 Dec 8. German.


High-frequency oscillatory ventilation with and without arteriovenous extracorporeal lung assist in patients with severe respiratory failure.

Kredel M, Brederlau J, Wunder C, Wurmb TE, Kranke P, Roewer N, Muellenbach RM.

J Crit Care. 2012 Apr;27(2):182-91. doi: 10.1016/j.jcrc.2011.08.007. Epub 2011 Oct 26.


Delayed systemic air embolism in a child with severe blunt chest trauma treated with high-frequency oscillatory ventilation.

Brederlau J, Muellenbach RM, Wunder C, Schwemmer U, Kredel M, Roewer N, Wurmb T.

Can J Anaesth. 2011 Jun;58(6):555-9. doi: 10.1007/s12630-011-9485-7. Epub 2011 Mar 24.


Pulmonary effects of positive end-expiratory pressure and fluid therapy in experimental lung injury.

Kredel M, Muellenbach RM, Schlegel N, Wunder C, Klingelhöfer M, Lange M, Roewer N, Waschke J, Brederlau J.

Exp Lung Res. 2011 Feb;37(1):35-43. doi: 10.3109/01902148.2010.514023. Epub 2010 Nov 15.


Whole-body multislice computed tomography (MSCT) improves trauma care in patients requiring surgery after multiple trauma.

Wurmb TE, Quaisser C, Balling H, Kredel M, Muellenbach R, Kenn W, Roewer N, Brederlau J.

Emerg Med J. 2011 Apr;28(4):300-4. doi: 10.1136/emj.2009.082164. Epub 2010 Jul 20.


High-frequency oscillation combined with arteriovenous extracorporeal lung assist reduces lung injury.

Muellenbach RM, Kredel M, Wilhelm J, Küstermann J, Fink L, Siebenlist G, Klosterhalfen B, Foerster CY, Kranke P, Wunder C, Roewer N, Brederlau J.

Exp Lung Res. 2010 Apr;36(3):148-58. doi: 10.3109/01902140903214683. Erratum in: Exp Lung Res. 2011 Mar;37(2):130. Siebenliest, Gregor [corrected to Siebenlist, Gregor].


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